Simvastatin API, Raw Material Powder CAS 79902-63-9
China Simvastatin Suppliers, China Simvastatin Manufacturers CAS 79902-63-9 Product Name: Simvastatin API, Raw Material Powder CAS 79902-63-9 Characteristics: A white or almost white crystalline powder Assay: 98.0% ~ 101.0% Simvastatin Formula: C25H38O5 Structure Formula: Package information: 25Kgs/Drum KEY...
China Simvastatin Suppliers, China Simvastatin Manufacturers CAS 79902-63-9
Product Name: Simvastatin
CAS Number: 79902-63-9
Characteristics: A white or almost white crystalline powder
Assay: 98.0% ~ 101.0% Simvastatin
Simvastatin is a lipid-lowering substance. It is the working API in medication. If Simvastatin is used along with exercise, diet, and weight loss, it will decrease elevated lipid levels.
The primary uses of Simvastatin are to fight against dyslipidemia and prevent atherosclerosis-related complications like heart attacks, stroke. Simvastatin decreases the risk of heart problems in those at high risk. Simvastatin is recommended to be used as an addition to a low cholesterol diet.
Simvastatin will mostly taken by mouth. Preparations in the market are Simvastatin Pills or tablets.
Simvastatin is belongs to a group of drugs called "statins."
It will lower the "bad" cholesterol levels, while higher the levels of "good" cholesterol. Also Simvastatin will help to reduce triglycerides in the blood.
By this way, it will help us to reduce the risk of getting stroke, heart attack, and other heart complications in people with diabetes, coronary heart disease, or other risk factors.
Simvastatin is only suggested to be used in adults or at least 10-year- old Children.
The primary application of Simvastatin API, Raw Material Powder is for the treatment of dyslipidemia and the prevention of cardiovascular disease. It is recommended to be used only after other measures such as diet, exercise, and weight reduction have not improved cholesterol levels.
Simvastatin API, Raw Material Powder is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood. Simvastatin API, Raw Material Powder belongs to a group of medicine named "statins", also called HMG-CoA reductase inhibitors. It acts by reducing cholesterol produced by the liver. Lowering "bad" cholesterol and triglycerides and raising "good" cholesterol will effectively minimize the risk of heart disease and prevent strokes and heart attacks.
By lowering cholesterol, Simvastatin API, Raw Material Powder help to prevent the buildup of plaque in blood vessels, which is the very reason for atherosclerosis (hardening of the arteries), heart disease, and stroke.
Simvastatin API, Raw Material Powder can be applied to help prevent heart disease in those who don't have it but are at risk, and in those who have already had some form of cardiovascular disease, such as a stroke or heart attack.
Pharmacology & Mechanism of Actions:
Simvastatin API, Raw Material Powder, just like other statins, functions by inhibiting HMG-CoA reductase, the rate-limiting enzyme of the HMG-CoA reductase pathway, the metabolic pathway responsible for the endogenous production of cholesterol.
Simvastatin API, Raw Material is in the form of an inactive lactone that is hydrolized after ingestion to produce the active agent.
Simvastatin API, Raw Material Powder is a white, nonhygroscopic, crystalline powder. It is practically insoluble in water, and freely soluble in chloroform, methanol and ethanol.
Grapefruit contains the flavanones naringenin and bergamottin, which will inhibit the liver cytochrome P450 3A4. This in turn slows metabolization of simvastatin and many other medicines. Therefore, people who are taking simvastatin should restrict their intake of grapefruit and grapefruit-containing products.
As a professional China Simvastatin API, Raw Material Powder BP EP USP supplier and Manufacturer in China, FENGCHEN GROUP CO., LTD has been supplying and exporting Simvastatin API, Raw Material Powder BP EP USP from China in China for almost 10 years.
Side effects of Simvastatin:
There can be constipation, headaches, and nausea
Even more seriously, there can be liver problems, muscle breakdown, and increased blood sugar levels.
Note: Please use a lower dose of Simvastatin in people with kidney problems.
Common side effects (>1% incidence) of Simvastatin API, Raw Material Powder may include indigestion, abdominal pain, diarrhea, a general feeling of weakness, etc.
There can also be some rare side effects, such as memory loss, joint pain, muscle cramps, etc. Cholestatic hepatitis, hepatic cirrhosis, rhabdomyolysis and myositis have been reported in patients receiving Simvastatin API, Raw Material Powder chronically.
Main indexes of Simvastatin:
A white or almost white crystalline powder
Specific Optical Rotation
+285° ~ +298°
Loss on drying
Residual on Ignition
Lovastatin and epilovastatin
Any other single impurity
Assay -- Simvastatin
98.0% ~ 101.0% Simvastatin
Top Quality, China Pure Simvastatin Powder/Substance factory in China; China Simvastatin Raw Material Suppliers in China. China Simvastatin API Manufacturers in China.
If you are looking for the Simvastatin API, Raw Material Powder CAS 79902-63-9, welcome to contact us. We are one of the leading and professional China manufacturers and suppliers in this field. Competitive price and good after-sale service are available.