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Irbesartan powder Raw Material BP, EP, USP CAS 138402-11-6

Irbesartan powder Raw Material BP, EP, USP CAS 138402-11-6

China Irbesartan Suppliers, China Irbesartan Manufacturers CAS 138402-11-6 Product Name: Irbesartan powder Raw Material BP, EP, USP CAS 138402-11-6 Synonym s: Irbesartan CAS Number: 138402-11-6 Characteristics: White crystalline powder Assay: 98.0% ~ 102.0% Irbesartan Formula: C25H28N6O Structure Formula: KEYWORD: Irbesartan Standard:...

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China Irbesartan Suppliers, China Irbesartan Manufacturers CAS 138402-11-6

Irbesartan powder Raw Material BP, EP, USP.jpg

Product Name:   Irbesartan powder Raw Material BP, EP, USP

Synonyms:  Irbesartan

CAS Number: 138402-11-6

Characteristics: White crystalline powder

Assay:  98.0% ~ 102.0% Irbesartan

Formula: C25H28N6O

Structure Formula:

Irbesartan powder Raw Material BP, EP, USP formula.gif

KEYWORD: Irbesartan powder Raw Material BP, EP, USP

Standard: Irbesartan USP Standard

Melting Point: 180-181 °C

Package: According to client’s requirement.

 

Description & Mechanism % Usage of Irbesartan:  

Irbesartan powder Raw Material BP, EP, USP is an antihypertensive substance. It belongs to angiotensin II receptor antagonists. The actions, uses and adverse effects of Irbesartan are similar to those of losartan. Irbesartan can be used alone. And it can also be applied together with other anti-hypertensive raw materials to control hypertension and other cardiovascular disorders.

Oral administration of Irbesartan reduces angiotensin II (AII)-induced hypertension, equipotent with losartan in conscious normotensive rats, markedly more active than losartan (10 mg/kg) in normotensive cynomolgus monkeys. 

Administration of Irbesartan significantly prevents skeletal muscle apoptosis and muscle.

Irbesartan is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.

Irbesartan is a nonpeptide angiotensin II antagonist. It has antihypertensive activity. 

Irbesartan selectively and competitively blocks the binding of angiotensin II to the angiotensin I receptor. it is an angiotensin II receptor blocker used alone or in combination with other agents in the therapy of hypertension and diabetic nephropathy. 

 

Irbesartan powder Raw Material BP, EP, USP is an antihypertensive substance. It belongs to angiotensin II receptor antagonists. The actions, uses and adverse effects of Irbesartan are similar to those of losartan. Irbesartan can be used alone. And it can also be applied together with other anti-hypertensive raw materials to control hypertension and other cardiovascular disorders.

 

Certificate of analysis of Irbesartan:

Test Items

Specifications

Appearance

Irbesartan

White to almost white crystalline powder

Solubility

Irbesartan

Slightly soluble in alcohol and in methylene chloride;   practically insoluble in water

Identification

Irbesartan

A: Infrared Absorption spectrum is identical to that of   Irbesartan reference standard

B: The retention time of the major peak of the sample solution   corresponds to that of the Standard solution, as obtained in the Assay

Related substances

Related compound A: ≤0.5%

Individual impurity: ≤0.1%

Total impurity:≤0.5%

Residual solvents

Toluene: ≤890ppm

Methylene chloride: ≤600ppm

N,N-Dimethylformamide: ≤880ppm

Ethanol: ≤5000ppm

Water

≤0.5%

Limit of azide

≤10ppm

Heavy metal

≤20ppm

Conclusion

Comply with USP38

 

Top Quality, China Pure Irbesartan Powder/Substance factory in China; China Irbesartan Raw Material Supplier in China. China Irbesartan API Manufacturer in China. 


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Irbesartan Powder Raw Material BP, EP, USP CAS 138402-11-6


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Skype: frankrenful2002
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