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Berberine Hydrochloride or Berberine Hcl CAS 141433-60-5 Powder API Raw Material

Berberine Hydrochloride or Berberine Hcl CAS 141433-60-5 Powder API Raw Material

Berberine Hydrochloride or Berberine Hcl CAS 141433-60-5 Powder API Raw Material Product Name: Berberine Hydrochloride Synonyms: Berberine Hcl CAS Number: 141433-60-5 Characteristics: Yellow crystalline powder Formula: C20H18ClNO4 Structure Formula: KEY Words: Berberine Hydrochloride, Berberine Hcl Package: 25Kgs/Drum...

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Berberine Hydrochloride or Berberine Hcl CAS 141433-60-5

Berberine Hydrochloride or Berberine Hcl  Powder API Raw Material.png


Product Name: Berberine Hydrochloride

Synonyms: Berberine Hcl

CAS Number: 141433-60-5

Characteristics: Yellow crystalline powder 

Formula:  C20H18ClNO4

Structure Formula: 

Berberine Hydrochloride or Berberine Hcl  Powder API Raw Material formula.png

KEY Words: Berberine Hydrochloride, Berberine Hcl Powder API Raw Material BP, EP, USP

Package: 25Kgs/Drum

Description: 

Berberine hydrochloride Powder API Raw Material BP, EP, USP is an isoquinoline alkaloid isolated from a variety of Chinese herbs, including Coptidis rhizoma, Phellodendron chinense schneid, and Phellodendron amurense. It has diverse pharmacological actions. Berberine hydrochloride Powder API Raw Material BP, EP, USP also has anti-diabetic and anti-lipid peroxidation activity, as well as an anti-atherosclerotic action, and also has neuroprotective properties and Berberine hydrochloride Powder API Raw Material BP, EP, USP will improve polycystic ovary syndrome. Pharmaceutically, Berberine hydrochloride Powder API Raw Material BP, EP, USP is widely utilized as an anti-bacterial, anti-fungal, and anti-inflammatory ingredient. Moreover, Berberine hydrochloride Powder API Raw Material BP, EP, USP has been used as a gastrointestinal remedy for thousands of years in China.

 

With a long history, Berberine hydrochloride Powder API Raw Material BP, EP, USP is a bitter-tasting alkaloid in both Chinese and Ayurvedic medicine, primarily to support gastrointestinal function. Berberine hydrochloride Powder API Raw Material BP, EP, USP has showed significant properties against a wide variety of organisms including a broad spectrum of bacteria, yeasts, fungus and parasites. Its mechanism of action is thought to result in part from its characteristic structure, which is that of a planar catonic molecule. In addition, Berberine hydrochloride Powder API Raw Material BP, EP, USP has been shown to be supportive of healthy blood sugar levels, including fasting and postprandial blood glucose, and HbA1c as well. Berberine hydrochloride Powder API Raw Material BP, EP, USP has been proven to be supportive of normal blood lipid levels, with the apparent mode of action being described as an increase in the production of a receptor protein in the liver which binds LDL-cholesterol, preparing it for elimination.

 

Berberine Hydrochloride belongs to the family of Alkaloids and Derivatives. It is naturally occurring chemical compounds which contains mostly basic nitrogen atoms. In addition to carbon, hydrogen and nitrogen, Berberine Hcl may also contain oxygen, sulfur and more rarely other elements such as chlorine, bromine, and phosphorus

Berberine Hcl is a quaternary ammonium salt from the protoberberine group of isoquinoline alkaloids. It is found in such plants as Berberis, Berberis vulgaris, and Berberis aristata, Hydrastis canadensis, Phellodendron amurense, etc.  Berberine Hcl is usually found in the roots, rhizomes, stems, and bark .  

Functions:
1. Berberine Hydrochloride has recently found that anti-arrhythmic effect.  
2. Berberine Hydrochloride (commonly known as Berberine Hcl) has been widely used to treat gastroenteritis, bacillary dysentery and so on, tuberculosis, scarlet fever, acute tonsillitis and respiratory infections also have a certain effect.
3. against MRSA infection.
4. Berberine Hcl is a component of some eye drop formulations for the treatment of trachoma, leishmaniasis.
5. Berberine Hcl prevents and suppress proinflammatory cytokines, E-selectin, and genes, and increases adiponectin expression which partly explains its versatile health effects.


1. Berberine hydrochloride Powder API Raw Material BP, EP, USP is characterized by a diversity of pharmacological effects. It has anticancer activity and the chance of regulating glucose and lipid metabolism in cancer cells showing more potential than ever.
2. Berberine Hcl Powder API Raw Material BP, EP, USP has anti-fungi properties. 
3. Berberine Hcl Powder API Raw Material BP, EP, USP has significant reductive ability and radicals scavenging effects, especially on ABTS, hydroxyl radicals and DPPH radicals. 
4. Berberine hydrochloride Powder API Raw Material BP, EP, USP can significantly attenuate neutrophil infiltration, suppress myeloperoxidase activity, decrease NO, TNF-αand IL-1βproduction, inhibits the phosphorylation of the NF-κB p65 subunit and the degradation of its inhibitor, IκBα, thus, exerts potent anti-inflammatory effects on LPS-induced mouse endometritis. 
5. Berberine Hcl Powder API Raw Material BP, EP, USP can prevent adhesion by downregulating ICAM-1 and reduce inflammation by inhibiting the TAK1/JNK and TAK1/NF-κB signaling after abdominal surgery, which brings out a good therapeutic approach for the development of clinical application for postoperative abdominal adhesion and inflammation. 

 

Main function of Berberine hydrochloride Powder API Raw Material BP, EP, USP:

1.As a traditional medicine or dietary supplement, Berberine hydrochloride Powder API Raw Material BP, EP, USP has activities against fungal infections, Candida albicans, yeast, parasites, and bacterial/viral infections. Berberine seems to exert synergistic effects with fluconazole even in drug-resistant C. albicans infections.

2. Some research has been undertaken into possible use against MRSA infection.

3. Berberine hydrochloride Powder API Raw Material BP, EP, USP is considered to be a antibiotic. When utilized in conjunction with methoxyhydnocarpin, an inhibitor of multidrug resistance pumps, Berberine Hcl will inhibit the growth of Staphylococcus aureus and Microcystis aeruginosa a toxic cyanobacterium.

4. Berberine Hydrochloride Powder API Raw Material BP, EP, USP is a component of some eye drop formulations. There is some evidence that it is very useful in the treatment of trachoma, and it has been a standard treatment for leishmaniasis.

5. Berberine Hcl Powder API Raw Material BP, EP, USP will help to prevent and suppresse proinflammatory cytokines, Eselectin, and genes, and increases adiponectin expression which partly explains its versatile health effects. Berberine hydrochloride Powder API Raw Material BP, EP, USP is a nucleic acid binding isoquinolone alkaloid with wide potential therapeutic properties.

 


COA of Berberine Hydrochloride

Testing Item

Standard

Result

Appearance
Berberine Hydrochloride

Yellow crystalline powder

Complies

Identification
Berberine Hcl

Should comply.

Complies

Other Alkaloid

Should comply

Complies

Loss on drying

≤12 %

11.2%

Residual on Ignition

≤0.2%

0.08%

Assay (On Dry Basis)
Berberine Hcl

≥ 97.0%
     Berberine Hydrochloride

99.2%

Other Indexes as following: Odor:Inodorous
Taste: Extremely Bitter
Loss on Drying: 12.0%
Ash: 0.2%
Jateorhizine&Palmatine: 1.0%
Related Matters: 2.0%
Heavy Metals: 10ppm
Pb: 1ppm
As: 1ppm
Total Plate Count: 1000cfu/g
Yeast&Mold: 100cfu/g
E.Coli:Negative
Salmonella:Negative


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If you are looking for the Berberine Hydrochloride or Berberine Hcl CAS 141433-60-5 Powder API Raw Material, welcome to contact us. We are one of the leading and professional China manufacturers and suppliers in this field. Competitive price and good after-sale service are available.
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