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Atorvastatin Calcium Trihydrate USP BP EP CAS 344423-98-9 Or 134523-03-8

Atorvastatin Calcium Trihydrate USP BP EP CAS 344423-98-9 Or 134523-03-8

Atorvastatin Calcium Trihydrate USP BP EP CAS 344423-98-9 or 134523-03-8 Product Name: Atorvastatin Calcium Trihydrate Synonym s: Atorvastatin Calcium salt, Atorvastatin Calcium hydrate; Calcium Hydrate, Atorvastatin CAS Number: -Atorvastatin Calcium Anhydrous CAS 134523-03-8 -Atorvastatin...

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Atorvastatin Calcium Trihydrate USP BP EP CAS 344423-98-9 or 134523-03-8

Atorvastatin Calcium Trihydrate USP BP EP.jpg

Product Name:  Atorvastatin Calcium Trihydrate Raw Material, API

Synonyms:  Atorvastatin Calcium salt, Atorvastatin Calcium hydrate; Calcium Hydrate, Atorvastatin Raw Material, API

CAS Number:

-Atorvastatin Calcium Anhydrous CAS 134523-03-8

-Atorvastatin Calcium Trihydrate CAS 344423-98-9

Characteristics: White Crystalline powder.

Assay:  98.0% ~ 102.0%

KEYWORD: Atorvastatin Calcium, Atorvastatin Raw Material, API

Formula: C66H74CaF2N4O13

Atorvastatin Calcium Trihydrate USP BP EP formula.jpg

Package: 10Kgs/Drum

 

Description: Atorvastatin Calcium Trihydrate Raw Material, API is the calcium salt of Atorvastatin. It is a synthetic lipid-lowering medicine. Atorvastatin Calcium Trihydrate competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, and lowers plasma cholesterol and lipoprotein levels.

Like other statins, Atorvastatin Calcium Trihydrate may Raw Material, API also display direct anti-neoplastic activity. It is believed that it will inhibit farnesylation and geranylgeranylation of proteins. For example, small GTP-binding proteins, which may result in the arrest of cells in the G1 phase of the cell cycle.

Atorvastatin calcium trihydrate is a pyrrole and heptanoic acid derivative with the function of reducing serum levels of LDL-CHOLESTEROL; APOLIPOPROTEIN B; AND TRIGLYCERIDES. It also can increase serum levels of HDL-CHOLESTEROL in the treatment of HYPERLIPIDEMIAS. What is more, Atorvastatin calcium trihydrate can also prevent CARDIOVASCULAR DISEASES in patients with multiple risk factors.

 

Usage:

Atorvastatin Calcium Trihydrate is used to lower plasma cholesterol levels. The main uses of Atorvastatin Calcium Trihydrate is for the treatment of dyslipidemia, hypercholesterolemia, combined hyperlipidemia and the prevention of cardiovascular disease. Atorvastatin Calcium Trihydrate is mostly made into tablets for oral administration.

 

As a professional China Atorvastatin Calcium Trihydrate Raw Material supplier and Manufacturer in China, FENGCHEN GROUP CO., LTD has been supplying and exporting Atorvastatin Calcium Trihydrate API from China in China for almost 10 years.

Fengchen Group’s Atorvastatin Calcium Trihydrate can be produced according to client’s orders. Our Atorvastatin Calcium Trihydrate API, Raw Material BP, USP, EP is manufactured and exported to all Middle East countries and the other continents like Uzbekistan, Thailand, Bangladesh, Vietnam, Cambodia, Russia, Belarus, Lithuania, Slovenia, Newzealand, Belarus, Ukraine, Korea, Japan, etc.

 

Other information:
Atorvastatin calcium is a white to off-white crystalline powder. It is insoluble in aqueous solutions of pH 4 and below. Atorvastatin calcium is very slightly soluble in distilled water, pH 7.4 phosphate buffer, and acetonitrile, slightly soluble in ethanol, and freely soluble in methanol.
 Atorvastatin Calcium Trihydrate
is a synthetic lipid-lowering substance. It is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyzes the conversion of HMG-CoA to mevalonate, an early and rate-limiting step in cholesterol biosynthesis.
Generally speaking, Atorvastatin Calcium will effectively lower blood cholesterol. It also stabilizes plaque and prevents strokes through anti-inflammation and other mechanisms. Just like all statins, Atorvastatin Calcium works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.

 

COA of Atorvastatin Calcium

Name    of Product

Atorvastatin    Calcium

Testing Item

Standard

Result

Identification A

Conforms to the spectrum obtained with    CRS--    Atorvastatin Calcium

Complies

Identification B

Calcium Test: Positive

Positive

Enantiomeric Purity

≤    0.3%

Not detected

Atorvastatin Diamino

≤    0.15%

Not detected

Atorvastatin Related    Compound A

≤    0.3%

0.07%

Atorvastatin Related    Compound B

≤    0.3%

0.04%

Atorvastatin Related    Compound C

≤    0.3%

Not detected

Atorvastatin    3-deoxy-yhept-2-enoic Acid

≤    0.1%

Not detected

Atorvastatin Related    Compound H

≤    0.15%

0.05%

Atovastatin epoxy    Tatrahydrofuran Analog

≤    0.15%

Not detected

Atorvastatin ethyl    ester

≤    0.15%

Not detected

Atorvastatin Related    Compound D

≤    0.15%

Not detected

Atorvastatin Related    Compound I

≤    0.15%

Not detected

Any other individual    impurity

≤    0.1%

0.04%

Total Impurities

≤    1.0%

0.2%

Water

3.5%    ~ 5.5%

4.5%

Methanol

≤    0.3%

0.02%

Ethanol

≤    0.5%

0.002%

N-Heptane

≤    0.5%

0.003%

Toluene

≤    0.089%

Not detected

Assay    (Atorvastatin Calcium)

98.0%    ~ 102.0%

99.9%

Top Quality, China Pure Atorvastatin Calcium Powder/Substance factory in China; China Atorvastatin Calcium Raw Material Supplier in China. China Atorvastatin Calcium API Manufacturer in China. 


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Atorvastatin Calcium Trihydrate USP BP EP CAS 344423-98-9 Or 134523-03-8


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Skype: frankrenful2002
E-Mail: frank_feng@fengchengroup.com
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WECHAT: +86-18678461007
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Add: Room 1101, 5th Building, No.168 Shenzhen Road, Qingdao, China
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