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Ambroxol Hcl CAS 18683-91-5 Ambroxol Hydrochloride CAS 23828-92-4

Ambroxol Hcl CAS 18683-91-5 Ambroxol Hydrochloride CAS 23828-92-4

Ambroxol Hcl CAS 18683-91-5 Ambroxol Hydrochloride CAS 23828-92-4 powder API, Raw Material Keywords: Ambroxol Hcl, Ambroxol Hydrochloride, Ambroxol Application of Ambroxol base and Ambroxol Hcl: Cough and phlegm Description and usage: Ambroxol Hydrochloride or Ambroxol Hcl is a bronchosecretolytic drug. It is a...

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Product Details

Ambroxol Hcl CAS 18683-91-5 Ambroxol Hydrochloride CAS 23828-92-4

Ambroxol Hcl, Ambroxol Hydrochloride.png

Product Name:

Ambroxol Base

Ambroxol Hcl

Synonyms:

trans-4-[[(2-Amino-3,5-dibromo-phenyl)methyl]amino]-cyclohexanol

Ambroxol Hydrochloride

Characteristics:

White or yellowish crystalline powder

White or yellowish crystalline powder

CAS Number:

18683-91-5

23828-92-4

Formula:

C13H18Br2N2O

C13H19Br2ClN2O

Structure:

Ambroxol Hcl, Ambroxol Hydrochloride formula.png

Ambroxol Hcl, Ambroxol Hydrochloride structure.png

Package:

25Kgs/drum

25Kg/Fiber DrumCardboard DrumPaper Drum

Keywords: Ambroxol Hcl, Ambroxol Hydrochloride, Ambroxol Powder API, Raw Material

Application of Ambroxol base and Ambroxol Hcl:
Cough and phlegm

Description and usage:
Ambroxol Hydrochloride or Ambroxol Hcl is a bronchosecretolytic drug. It is a secretolytic active substance which will treat diseases associated with viscid or excessive mucus.
Ambroxol Hydrochloride is the active ingredient
Ambroxol Hydrochloride and Ambroxol Hcl is a mucoactive drug. It has several properties such as secretolytic and secretomotoric actions which restore the physiological clearance mechanisms of the respiratory tract. It plays an important role in the body’s natural defending mechanisms.
Ambroxol Hydrochloride and Ambroxol Hcl is often administered as an active ingredient in cough syrups or some oral solutions.
Ambroxol Hydrochloride and Ambroxol Hcl promotes mucus clearance, facilitates expectoration and eases productive cough. These will help patients to breathe freely and deeply.
Ambroxol Hydrochloride tablets or pills, dry powder sachets are also available in most drug stores.
Ambroxol also relievess pain sore in throat.
Local Anaesthetic effect allow Ambroxol Hydrochloride and Ambroxol Hcl treating sore throat. 
Further more, Ambroxol Hcl is a potent inhibitor of the neuronal Na+ channels.

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Ambroxol Hcl CAS 18683-91-5 Ambroxol Hydrochloride is a clinically proven systemically active mucolytic agent. When administered orally onset of action occurs after about 30 minutes. The breakdown of acid mucopolysaccharide fibers makes the sputum thinner and less viscous and therefore more easily removed by coughing. Although sputum volume eventually decreases, Ambroxol Hcl CAS 18683-91-5 Ambroxol Hydrochloride’s viscosity remains low for as long as treatment is maintained.

 

Indications of Ambroxol Hcl, Ambroxol Hydrochloride:

Ambroxol Hcl, Ambroxol Hydrochloride Raw Material, API indicates for almost all forms of tracheobronchitis, emphysema with bronchitis pneumoconiosis, chronic inflammatory pulmonary conditions, bronchiectasis, bronchitis with bronchospasm asthma. During acute exacerbations of bronchitis Ambroxol Hcl, Ambroxol Hydrochloride Raw Material, API should be taken together with the appropriate antibiotic.

 

Side effects of Ambroxol Hcl, Ambroxol Hydrochloride Raw Material, API:

Occasional gastrointestinal side effects may occur but they are normally mild.

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Ambroxol Hcl, Ambroxol Hydrochloride Raw Material, API is a medication indicated to alleviate chest congestion associated with conditions that include bronchitis, pneumonia and bronchospasm asthma. Ambroxol Hcl, Ambroxol Hydrochloride Raw Material, API is part of a class of drugs named mucolytics and functions by thinning chest mucus in affected people. Although Ambroxol Hcl, Ambroxol Hydrochloride Raw Material, API is not currently marketed in the United States, it is widely accepted in most other countries in the world.

 

As a professional China Ambroxol Hcl, Ambroxol Hydrochloride Raw Material, API supplier and Manufacturer in China, FENGCHEN GROUP CO., LTD has been supplying and exporting Ambroxol Hcl, Ambroxol Hydrochloride Raw Material, API from China in China for almost 10 years.

 

Metabolism:

Studies in human liver microsomes showed that CYP3A4 is the predominant isoform for ambroxol metabolism. Otherwise Ambroxol Hcl, Ambroxol Hydrochloride Raw Material, API is metabolised in the liver mainly by conjugation.

Elimination:

Around thirty percents of Ambroxol Hcl, Ambroxol Hydrochloride Raw Material, API will be eliminated via the first-pass effect. The terminal half-life is about 600 Minutes.

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General Description & Applications:

Ambroxol Hcl, Ambroxol Hydrochloride Raw Material, API is a metabolite of bromhexine. It is an expectoration improver and mucolytic agent used in the treatment of acute and chronic disorders characterized by the production of excess or thick mucus. Ambroxol Hcl, Ambroxol Hydrochloride Raw Material, API works to decrease mucus viscosity by altering its structure. It is chemically described as trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol. Ambroxol Hcl, Ambroxol Hydrochloride Raw Material, API is a white to yellowish crystalline powder; slightly soluble in water, ethanol; soluble in dimethylformamide, methanol; insoluble in chloroform and benzene; melting point 240 C; administered orally.

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Indexes of Ambroxol Hydrochloride or Ambroxol Hcl:


     Testing Item

Standard

Result

Appearance
Ambroxol Hydrochloride

White or yellowish crystalline powder

Complies

Identification A
Ambroxol Hcl

Ultraviolet and visible absorption spectrophotometry

Complies

Identification B
Ambroxol Hydrochloride

Infrared Absorption spectrophotometry

Complies

Identification C
Ambroxol Hcl

Thin-Layer chromatography

Complies

Identification D
Ambroxol Hydrochloride

Reaction of Chlorides

Complies

Solubility

Pass test of Ambroxol Hcl
     (Ambroxol Hydrochloride)

Complies

Appearance of solution

Clear and not deeper than reference Y6

Complies

pH

4.5 ~ 6.0

5.3

Loss on drying

≤ 0.5%

0.1%

Residual on Ignition

≤ 0.1%

0.05%

Heavy Metal

≤ 20ppm

< 20ppm

Impurity A,B,C,D,E

≤ 0.1%

Complies

Unspecified impurities

≤ 0.1%

0.02%

Total Impurity

≤ 0.3% 

0.05%

Assay -- Ambroxol Hcl

≥ 98.0% Ambroxol Hydrochloride

98.9%

Top Quality, China Pure Ambroxol Hcl, Ambroxol Hydrochloride Powder/Substance factory in China; China Ambroxol Hcl, Ambroxol Hydrochloride Raw Material Suppliers in China. China Ambroxol Hcl, Ambroxol Hydrochloride API Manufacturers in China. 


Related similar product you may interested:    

Ambroxol Hcl CAS 18683-91-5

Ambroxol Hydrochloride CAS 23828-92-4

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