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Metronidazole Powder Raw Material BP EP USP CAS 443-48-1

Metronidazole Powder Raw Material BP EP USP CAS 443-48-1

Metronidazole BP EP USP CAS 443-48-1 Product Name: Metronidazole Synonyms: Metronidazol, Metronidazolum , Meronidal CAS Number: 443-48-1 Characteristics: White or yellowish, crystalline powder. Assay: 99.0% ~ 101.0% Standard: EP / BP / USP Formula: C6H9N3O3 Package: 25Kgs/Drum Storage: Stay away...

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Metronidazole Powder Raw Material BP EP USP CAS 443-48-1

                                              Metronidazole Powder Raw Material BP EP USP.jpgProduct Name:  Metronidazole

Synonyms:  Metronidazol, Metronidazolum , Meronidal

CAS Number: 443-48-1

Chemical Name: 2-methyl-5-nitro-1H-imidazole-1-ethanol.

1-(2-hydroxy-1-ethyl)-2-methyl-5-nitroimidazole

Characteristics: White or yellowish, crystalline powder.

Assay:  99.0% ~ 101.0% Metronidazole

Standard: EP / BP / USP

Formula: C6H9N3O3 ; CC1=NC=C(N1CCO)[N+]([O-])=O

Metronidazole Powder Raw Material BP EP USP formula.jpg

Package: 25Kg/Fiber DrumCardboard DrumPaper Drum

Storage:  Stay away from water, heavy moisture. Extreme heat and direct light.

 

Description of Metronidazole: :

Metronidazole is a synthetic substance with anti-protozoal and anti-bacterial properties. Metronidazole belongs to nitroimidazole, containing an imidazole ring which bears a nitro group.. It can be used to treat  protozoa (eg. Amebiasis, Trichomonas, vaginalis and giardiasis). Metronidazole works especially well when it is against anaerobic bacterial infections. It is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea etc.

It can be used to treat infections related to trichomonas, amebiasis, or vaginitis. Metronidazole is also the active ingredient in medicines which fight againt giardiasis, anaerobic bacteria, treponemal infections. It is anticipated to be a carcinogen. Metronidazole has been proposed as a radiation sensitizer for hypoxic cells.

Metronidazole will treat anaerobic infections and some other mixed infections. The indications include surgical prophylaxis requiring anaerobic coverage, Clostridium difficile-associated diarrhea, colitis etc.

 Mechanism of Action:

Metronidazole is a the raw material, powder. It can be considered as a pro-drug. With the following process: Inhibiting bacterial nucleic acid synthesis, then cause the bacterial cell death.

 

As a professional China Metronidazole Powder supplier and Manufacturer, FENGCHEN GROUP CO., LTD has been supplying and exporting Metronidazole Powder from China for almost 10 years.


Usage:  Metronidazole is an antibiotic. It kill some bacteria in human or animal body.

Normally, Metronidazole is used to fight bacterial infections of the respiratory tract,  vagina, stomach and skin, etc.

It will be very easy to find Metronidazole Preparations in drug stores:  Metronidazole Tablets, Metronidazole Oral Suspension, Metronidazole Suppositories, Metronidazole Sterile Solution, Metronidazole Intravenous Infusion, Metronidazole Gel, etc.  Also it can be used to manufacture veterinary drugs. For example, for dogs and other animals.

Suppository:  With some Hard Fat or other Suppository Carrier, it can be made into Suppository.

 

Note: Metronidazole is not effective when fight against vaginal yeast infections.

 

Certificate of Analysis of Metronidazole: :

Name of   Product

Metronidazole

Testing Item

Standard

Result

Appearance (Metronidazole)

A white   or yellowish crystalline powder

Complies

solubility

Slightly   solube in water, in acetone, in alcohol and in methylene ,chloride

Complies

Identification

Should   Comply

Complies.  

Loss on drying

≤0.5%

0.20%

Residue   on ignition

≤0.1%

0.05%

Heavy   metals

≤20PPM

<   20PPM

Particle   size

40-80MESH

Complies

Microorganism   test

Total   barcterium<1000UFC/G

Fungi   and Mould<100UFC/G

Complies

Appearance   of solution

SUSPENSION   II

AND  SOLUTION    GY6

Complies

Related   substances:

Impurity   ≤0.1%

0.054%

Total   impurity ≤0.2%

0.090%

Disregard   limited ≤0.01%

Complies

Assay   (Metronidazole)

99.0% ~   101.0% Metronidazole

99.55%

Clinical pharmacology of Metronidazole:

The mechanisms by which metronidazole acts in the treatment of rosacea are unknown, but appear to include an anti-inflammatory effect.

 

Metronidazole raw material can be used to produce Metronidazole Cream, which is indicated for topical application in the treatment of inflammatory papules, pustules of rosacea, etc.

 

Precautions before using Metronidazole:

Metronidazole is highly contraindicated in individuals with a history of hypersensitivity to this substance,

Metronidazole has been reported to cause tearing of the eyes. Therefore, let’s avoid direct contact with the eyes. If a reaction suggesting local irritation occurs, patients should be directed to use the medication less frequently or discontinue use. Metronidazole is a nitroimidazole and should be used with care in patients with evidence of, or history of blood dyscrasia.


Top Quality, Pure Metronidazole Powder;  Metronidazole Raw Material Supplier in China. Metronidazole API Manufacturer. 

 

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Metronidazole Powder Raw Material BP EP USP CAS 443-48-1



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Skype: frankrenful2002
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Add: Room 1101, 5th Building, No.168 Shenzhen Road, Qingdao, China
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