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Mannitol Powder Raw Material, API CAS 69-65-8

Mannitol Powder Raw Material, API CAS 69-65-8

China Mannitol Suppliers, China Mannitol Manufacturers CAS 69-65-8 Product Name: D-Mannitol Synonyms: Mannitolum, Mannite CAS Number: 69-65-8 Characteristics: White crystalline powder. Assay: 98.0% ~ 102.0% Mannitol Formula: C6H14O6 = 182.2 Structure Formula: KEYWORD: Mannitol, D-Mannitol...

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China Mannitol Suppliers, China Mannitol Manufacturers CAS 69-65-8

Mannitol Powder Raw Material, API.jpg

Product Name: D-Mannitol, Mannitol Powder Raw Material, API CAS 69-65-8

Synonyms: Mannitolum, Mannite

CAS Number: 69-65-8

Characteristics: White crystalline powder.

Assay: 98.0% ~ 102.0% Mannitol

Formula: C6H14O6 = 182.2

Structure Formula:

Mannitol Powder Raw Material, API structure.jpg

KEYWORD: Mannitol, D-Mannitol Powder Raw Material, API CAS 69-65-8

Standard: BP, EP, USP Mannitol

Package: 25Kgs/Bag

Stability: D-Mannitol is Stable and Combustible. While D-Mannitol is incompatible with strong oxidizing agents.


Description:  

Mannitol is an Osmotic Diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place.

Mannitol can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function. Furthermore, Mannitol can also be used to determine glomerular filtration rate.

More over, Mannitol is commonly used as a research tool in cell biological studies.

Mannitol is a naturally existing alcohol, commonly found in fruits and vegetables.

Mannitol is freely filtered by the glomerulus and poorly reabsorbed from the renal tubule, thereby causing an increase in osmolarity of the glomerular filtrate.

In addition, Mannitol elevates blood plasma osmolarity. By this way, it will enhanced flow of water from tissues into interstitial fluid and plasma.

D-Mannitol is an osmotic diuretic agent and a weak renal vasodilator.

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Mannitol is a naturally occurring substance which will make the body losing water (diuresis) through osmosis. Mannitol helps to promote diuresis in kidneys by increasing the concentration of filtrates in the kidney and blocking water re-absorption by kidney tubules.

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Mannitol is an osmotic diuretic which is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol elevates blood plasma osmolality. As a result, it will enhance water from tissues, including the brain and cerebrospinal fluid, into interstitial fluid and plasma. Thus, cerebral edema, elevated intracranial pressure, and cerebrospinal fluid volume and pressure may be reduced. Those are the benefits.

 

As a professional China Mannitol BP, EP, USP Raw Material supplier and Manufacturer in China, FENGCHEN GROUP CO., LTD has been supplying and exporting Mannitol BP, EP, USP API from China in China for almost 10 years.

 

Mechanism of mannitol:

Mannitol has Osmotic Activity. The physiologic effect of mannitol is by means of Increased Diuresis.

 

Usage:

There is a lot of preparations available in market. For example, Mannitol Intravenous Infusion.

Mannitol may also be applied for the promotion of diuresis before irreversible renal failure becomes established; Mannitol will also promote urinary excretion of toxic substances; Mannitol sometimes may act as a renal function diagnostic aid.

 

COA of Mannitol:  Please contact us for the Certificate of Analysis.

 

Name of Product

Mannitol BP, EP, USP

Testing Item

Standard

Result

Appearance

White or almost white   crystalline powder or powder

Complies

Solubility

Freely soluble in water, practically insoluble in ethanol

Complies

Identification

Should comply.

Complies

Specific   Optical Rotation

+23° ~ +25°

+23.9°

Melting Point

165.0°C ~ 170.0°C

166.2°C ~ 167.2°C

Infrared Absorption

Should comply.

Complies

Appearance of solution

Clear and colorless

Complies

Conductivity

≤ 20μS/cm

1.3μS/cm

Reducing Sugars

≤ 0.1%

< 0.1%

Impurity A (Sorbitol)

≤ 2.0%

0.44%

Impurity B + C

(Maltitol + Isomalt)

≤ 2.0%

0.00%

Unspecified Impurity

≤ 0.1%

0.024%

Total Impurity

≤ 2.0%

0.50%

Nickel

≤ 1ppm

< 1ppm

Heavy Metal

≤ 5ppm

< 5ppm

Loss on drying

≤ 0.5%

0.10%

TAMC

≤ 1000cfu/g

10cfu/g

Total Yeast and Mould

≤ 100cfu/g

<   10cfu/g

Ecoli

Negative

Negative

Salmonella

Negative

Negative

Bacterial Endotoxins

< 2.5IU/g

< 2.5IU

Purity (Assay)

97.0% - 102.0%

100.0%





Complies with the BP, EP, USP Standard. 


Top Quality, China Pure Mannitol Powder/Substance factory in China; China Mannitol Raw Material Supplier in China. China Mannitol API Manufacturer in China. 


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Mannitol Powder Raw Material, API CAS 69-65-8

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If you are looking for the Mannitol Powder Raw Material, API CAS 69-65-8, welcome to contact us. We are one of the leading and professional China manufacturers and suppliers in this field. Competitive price and good after-sale service are available.
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