Rutin DAB10 Raw Material, API NF11 EP CAS 153-18-4
Rutin DAB10 Raw Material, API NF11 EP CAS 153-18-4 Product Name: Rutin DAB10 NF11 EP Synonyms: Bioflavonoids, Sophora Japonica L. CAS Number: 153-18-4 Characteristics: Greenish-yellow Crystalline Powder Assay: 98.5% --102% Standard: DAB10, NF11 Formula: C27H30O16 Structure: Package: 25Kgs /Drum Shelf life: 24...
Rutin DAB10 NF11 EP Raw Material CAS 153-18-4
Product Name: Rutin DAB10 NF11 EP, Raw Material, API
Synonyms: Bioflavonoids, Sophora Japonica L.
CAS Number: 153-18-4
Characteristics: Greenish-yellow Crystalline Powder
Assay: 98.5% --102%
Standard: DAB10, NF11
Shelf life: 24 months
Keywords: Rutin, Rutin Extract
Functions of Rutin:
1.Improve blood circulation status.
2.Prevents some blood clots
4. Treat some allergies.
NOTE: Pregnant women should not use Rutin.
Rutin is a flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc. It has been used therapeutically to decrease capillary fragility.
Rutin is a flavonoid known to have a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.
Rutin acts as a quercetin deliverer to the large intestine; moreover, quercetin is extensively metabolized in the large intestine, which suggests that quercetin liberated from Rutin and/or its colonic metabolites may play a role.
Rutin's anti-inflammatory actions are mediated through a molecular mechanism that underlies the quercetin-mediated therapeutic effects.
Rutin is a flavonoid, also known as rutoside, sophorin and quercetin-3-O-rutinoside. Rutin is chemically described as the glycoside between disaccharide rutinose and quercetin, another flavonoid.
Natural sources of Rutin
We can extract Rutin from sophora japonica bud, buckwheat, etc.
Rutin is a citrus flavonoid glycoside found in many plants including buckwheat, the leaves and petioles of Rheum species, and asparagus. Tartary buckwheat seeds have been found to contain more rutin (about 0.8-1.7% dry weight) than common buckwheat seeds (0.01% dry weight). Rutin is also found in the fruit of the fava d'anta tree (from Brazil), fruits and flowers of the pagoda tree, fruits and fruit rinds (especially the citrus fruits orange, grapefruit, lemon, and lime) and apple; berries such as mulberry, ash tree fruits, aronia berries and cranberries. Rutin is one of the primary flavonols found in 'clingstone' peaches. It is also found in green tea infusions.
As a professional China Pure Rutin Raw Material supplier and Manufacturer in China, FENGCHEN GROUP CO., LTD has been supplying and exporting Rutin API from China in China for almost 10 years.
Functions of rutin (Extracted Raw Material):
1. With the ability of strenthening and increasing flexibility in blood vessels, Rutin will improve our blood circulation remarkably.
2. Rutin Raw Material, API plays a good role for the blood clots prevention. This will helps to minimize chances of putting us into life-threatening conditions like heart attacks, stroke, pulmonary embolisms, deep vein thrombosis.
3. Pure Rutin API, Raw Material will also help us to lowers LDL cholesterol, a high level of which is a unwanted substance in our body.
4. Pure Rutin API, Raw Material can also relieve arthritis pains.
Application of Rutin:
1. In the bulk production, Rutin can be used to manufacture troxerutin API.
2. Pharmaceutical Grade Rutin is commonly added into medicine and dietary products to give cardio-support, blood vessel support
3. Pure Rutin API, Raw Material can also be an Antioxidant: Rutin will scavenge superoxide radicals which are the most active form of free radicals.
4. Working together with Ascorbic Acid, will make Rutin have a better effect.
Characteristic (Appearance): Rutin Raw Material, API is yellow or yellow-green powder or very fine needle-like crystal, odorless, tasteless, in the air gradually becomes darker, heated to 185-192 c into a jelly-brown.
Solubility: Rutin is difficult to dissolve in cold water (0.0013%), soluble in hot water (0.55%), hot methanol (11.2%), cold methanol (1.0%), hot ethanol (3.5 percent), cold ethanol (0.36%) cold pyridine (8.5 %). Rutin is soluble in alkaline, and acid precipitation. Rutin is Insoluble in other organic solvents.
Pharmacology: Pure Rutin API, as a extract of plant, the glycoside form of quercetin, is a bioflavonol having aromatic trimeric heterocyclic structure. Its chemical formula is 3-[[6-o-(6-deoxy-alpha-l-mannopyranosyl)-beta-d-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl) -5,7-dihydroxy-4h-1-benzopyran-4-one. Rutin is a yellow to greenish crystalline powder melting at 190 c. It is one of the substances which is classified as vitamin p which increases the strength of the walls of the blood capillaries and regulates their permeability. Others substances which classified as vitamin p are catechin, citrin, eriodictin, hesperetin, hesperidin, nobiletin, quercetin,sinensetin, and tangeretin. Rutin raw material isn’t a dietary essential but it is proven to have some good effect for treating capillary disorders. To some extent, Rutin also has antioxidant activity. It is also believed that Rutin has pharmacological properties as an anti-inflammatory, antihistaminic and antiviral substance.
Main Indexes –Rutin
Chemical & physical control
Greenish-yellow Crystalline Powder
Practically insoluble in water
Soluble in about 400parts of boiling water
Sparingly soluble in ethanol
Soluble in ammonia and solutions of alkali hydroxides
Positive,A B C
Impurity B: quercetin
Impurity C: Kaempferol 3-rutinoside
100% pass 80Mesh
Loss on drying
Total plate count
Yeast & mold
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