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Menadione Sodium Bisulfite CAS 130-37-0 Or Menadione Nicotinamide Bisulfite 96% CAS 73581-79-0 Vitamin K3

Menadione Sodium Bisulfite CAS 130-37-0 Or Menadione Nicotinamide Bisulfite 96% CAS 73581-79-0 Vitamin K3

Menadione Sodium Bisulfite CAS 130-37-0 or Menadione Nicotinamide Bisulfite 96% CAS 73581-79-0 Vitamin K3 Keywords: Menadione Sodium Bisulfite, Menadione Nicotinamide Bisulfite, Vitamin K3 powder, Menadione Sodium Sulfonate, Menadione Nicotinamide Sulfonate Description: Vitamin K3 also called...

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Menadione Sodium Bisulfite CAS 130-37-0 or Menadione Nicotinamide Bisulfite 96% CAS 73581-79-0 Vitamin K3

Menadione Sodium Bisulfite, Menadione Nicotinamide Bisulfite, Vitamin K3 powder.jpg

Product    Name:

Menadione Sodium Bisulfite

Menadione Nicotinamide Bisulfite

Synonyms:

MSB, Menadione Sodium Sulfonate
 Vitamin K3 Sodium Bisulfite

MNB, Menadione Nicotinamide Sulfonate
 Vitamin K3 Nicotinamide Bisulfite

Characteristics:

White    or similar-whiter crystalline Powder

White    Powder

CAS    Number:

130-37-0

73581-79-0

Formula:

C11H9NaO5S;
 C11H8O2NaHSO3·3H2O

C17H16N2O6S

Structure:

Menadione Sodium Bisulfite (MSB) vitamin K3.jpg

Menadione Nicotinamide Bisulfite (MNB) Vitamin K3.jpg

Package:

25Kgs/Drum

25Kgs/Drum

Keywords: Menadione Sodium Bisulfite, Menadione Nicotinamide Bisulfite, Vitamin K3 powder, Menadione Sodium Sulfonate, Menadione Nicotinamide Sulfonate Powder API, Raw Material BP, EP, USP.

Description:

Vitamin K3 also called Menadione fat-soluble vitamin precursor that is converted into menaquinone in the liver. Mostly, there are 2 kind of Vitamin K3:

1. Menadione Sodium Bisulfite (Menadione Sodium Sulfonate, MSB), with chemical name sodium 1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-2-naphthalenesulfonate;

2. Menadione Nicotinamide Bisulfite (Menadione Nicotinamide Sulfonate, MNB) with chemical name methyl 1,4-dioxo-2,3-dihydronaphthalene-2-sulfonate,pyridine-3-carboxamide.

Menadione Sodium Bisulfite is a synthetic naphthoquinone without the isoprenoid side chain. And there is no biological activity for Menadione Sodium Sulfonate.  Menadione Sodium Bisulfite can be converted to active VK2 after alkylation.

The well-known function of vitamin K3 is to assist in the normal clotting of blood. Menadione Sodium Bisulfite and Menadione Nicotinamide Bisulfite are also important in the process of bone calcification.

Now, Vitamin K3 is mainly manufactured by human being. Synthetic Menadione Sodium Bisulfite is yellowish crystalline.  Menadione Nicotinamide Bisulfite is converted into the active form of the K2 vitamin in animal and human body.

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Menadione Sodium Bisulfite (MSB, Vitamin K3)

Mode action- hemostatic.

Menadione Sodium Bisulfite (MSB, Vitamin K3) will help to increase coagulability of blood by increasing the production in the liver of factors II, VII, IX, X. The effect manifests itself 12-18 hours after the / m introduction. In the blood, prothrombin (factor II) in the presence of thromboplastin and calcium ions, with the participation of proconvertin (factor VII), factors IX and X passes into thrombin, under the influence of which fibrinogen turns into fibrin, which forms the basis of a blood clot (thrombus). With a deficiency of vitamin K3, whose synthetic homologue is menadione, there will be increased bleeding. Substrate stimulates K-vitamin reductase, activating vitamin K and will ensure its participation in hepatic synthesis of K-vitamin-dependent plasma factors of hemostasis. After the / m introduction is easily and quickly absorbed. After a cycle of metabolic activation, it will be oxidized to a diol form. It is excreted by the kidneys.

 

Application of the substance Menadione sodium bisulfite (MSB, Vitamin K3)

Bleeding in the background of hypoprothrombinemia: obstructive jaundice, hepatitis, parenchymal and capillary bleeding in wounds, surgical operations, ulcer and radiation sickness; Hemorrhoidal, uterine, pulmonary and prolonged nasal bleeding; Hemorrhagic phenomena in prematurity; Overdose of neodikumarina and other indirect anticoagulants.

 

Contraindications of Menadione sodium bisulfite (MSB, Vitamin K3):

Hypersensitivity, hypercoagulation, thromboembolism, hemolytic disease of the newborn.

 

Side effects of Menadione sodium bisulfite (MSB, Vitamin K3):

Hemolytic anemia, hyperbilirubinemia, jaundice, especially in prematurity, hemolysis in newborns with congenital deficiency of glucose-6-phosphate dehydrogenase.

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Other information of : Vitamin K3 - MSB Menadione Sodium Bisulfite

Molecular Formula: C11H9NaO5S•NH2O

Appearance: White Or Ivory White Crystalline Powder

Solubility: Water-Soluble

 

Menadione sodium bisulfite (MSB, Vitamin K3) Function:

It is crucial for the living of animals. Menadione sodium bisulfite (MSB, Vitamin K3) raw material API powder participates in the synthesis of hepatic prothrombin in our lever, takes a unique hemostatic effect and simultaneously prevents the animals from the weakness and subcutaneous hemorrhage. Menadione sodium bisulfite (MSB, Vitamin K3) can be utilized before the debarking of chick. Menadione sodium bisulfite (MSB, Vitamin K3) raw material, API powder is able to help reduce the bleeding, accelerate wound, and promote the growth. It will help to relieve or even avoid the toxicity reaction when taking with sulfa-drugs; Menadione sodium bisulfite (MSB, Vitamin K3) raw material, API powder will enhance diseases prevention by taking with anti-coccidian drug, such as white diarrhea and fowl cholera as well. With stress factors, the application of Menadione sodium bisulfite (MSB, Vitamin K3) raw material, API can relieve or even remove the stressful condition of animals while improving the effect of feed.

Specifications:

Menadione sodium bisulfite (MSB, Vitamin K3) 96:

Content Of Menadione ≥50.0%

Formulation:

Recommended Amount In The Formula Feed For Livestock:

Menadione sodium bisulfite (MSB, Vitamin K3): 2-10g Per Ton Of Compound Feed.

Recommended Amount In The Formula Feed For Aquatic:

Animals: Menadione sodium bisulfite (MSB, Vitamin K3): 4-32g Per Ton Of Compound Feed.

Packaging & Storage: 25kg/Carton Net or fiber drum, Inner Plastic Bag.

Storage: Menadione sodium bisulfite (MSB, Vitamin K3) raw material API should be stored in dry, cool and dark places.

 

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Stabilized Vitamin K3 - MNB Menadione Nicotinamide Bisulfite

Molecular Formula: C17H16N2O6S

Appearance/Solubility:

Appearance: White Or Ivory White Crystalline Powder

Solubility: Slightly Soluble In Water

Molecular Weight: M=376.42

 

Vitamin K3 - MNB Menadione Nicotinamide Bisulfite Function:

It is not only more stable and biologically active than Menadione sodium bisulfite (MSB), but also could reduce the addition of nicotinamide in the feed. Menadione Nicotinamide Bisulfite (MNB, Vitamin K3) raw material, API powder is very important for the life of animals.

Specification

Menadione Nicotinamide Bisulfite (MNB, Vitamin K3) raw material, API powder:

Assau Of Menadione 43.7% Min,

Assay Of Nicotinamide31.2% Min;

Menadione Nicotinamide Bisulfite (MNB, Vitamin K3) raw material, API powder Formulation:

- Recommended Amount In The Formula Feed For Livestock:

Menadione Nicotinamide Bisulfite (MNB, Vitamin K3) raw material, API powder: 2.5-11g Per Ton Of Compound Feed.

- Recommended Amount In The Formula Feed For Aquatic

Animals: Menadione Nicotinamide Bisulfite (MNB, Vitamin K3) raw material, API powder: 4.5-37g Per Ton Of Compound Feed.

Packaging & Storage: 25kg/ fiber drum or Carton Net, Inner Plastic Bag.

Storage: Menadione Nicotinamide Bisulfite (MNB, Vitamin K3) raw material, API powder should be kept in dry, cool and dark places.

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Vitamin K3 Overdose and Deficiency:

Vitamin K3 deficiency is dangerous, especially to infants. Lack of Menadione Nicotinamide Bisulfite will cause extensive hemorrhaging. Menadione Sodium Bisulfite overdose is equally detrimental. Vitamin K3 overdose may result in kernicterus.(It is af severe brain damage). This condition is associated with an abnormally high concentration of bilirubin, a bile pigment, in the tissues of the brain, which can be caused by the presence of K3.

For these reasons, Menadione Sodium Bisulfite and Menadione Nicotinamide Bisulfite is not as frequently used as before.

As a professional China Menadione sodium bisulfite (MSB, Vitamin K3), Menadione Nicotinamide Bisulfite (MNB, Vitamin K3) raw material supplier and Manufacturer, FENGCHEN GROUP CO., LTD has been supplying and exporting Menadione sodium bisulfite (MSB, Vitamin K3), Menadione Nicotinamide Bisulfite (MNB, Vitamin K3) API from China for almost 10 years. 

Menadione Sodium Bisulfite and Menadione Nicotinamide Bisulfite Detailed information.png

Side effects of Menadione Sodium Bisulfite and Menadione Nicotinamide Bisulfite:

Facial flushing, sweating, chest constriction/pain, dyspnoea, cyanosis, CV collapse. IM: Severe shock-like reactions, phlebitis, inj site reactions.

Indications of Menadione Sodium Bisulfite, Menadione Nicotinamide Bisulfite:

Orally taken or Intravenous given:

-Vitamin K deficiency.

-Severe hypoprothrombinaemia.

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Property of Menadione sodium bisulfite (Vitamin K3, MSB):

Name: Menadione sodium bisulfite

EINECS: 204-987-0

Menadione sodium bisulfite (Vitamin K3, MSB) CAS No.: 130-37-0

Solubility: Highly soluble in water

Menadione sodium bisulfite (Vitamin K3, MSB) Melting Point: 121-124 °C

Formula: C11H9NaO5S

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Property of :

Name: Menadione nicotinamide bisulfite (Vitamin K3, MNB)

EINECS: 277-543-7

Menadione nicotinamide bisulfite (Vitamin K3, MNB) CAS No.: 73581-79-0

Menadione nicotinamide bisulfite (Vitamin K3, MNB) Melting Point: 182 ºC

Formula: C17 H16 N2 O6 S

Boiling Point: 507.3 ºC at 760 mmHg

Molecular Weight: 376.39 .

Menadione nicotinamide bisulfite (Vitamin K3, MNB) Flash Point: 260.6 ºC

Appearance: pale yellow powder

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Certificate of Analysis of Menadione Sodium Bisulfite (MSB):

Testing    Item

Standard

Testing    Result

Appearance
 Menadione    Sodium Bisulfite

White    or similar-whiter crystalline Powder

White    crystalline powder

Odor

Slight    Olid or slight pungent

Slight    pungent

Menadione    Sodium Bisulfite
 (C11H8O2NaHSO3·3H2O)%

≥96.0%

96.6%

Menadione    %

≥50.0%

50.15%

H2O    %

≤13.0%

9.1%

Heavy    metals(as Pb)%

≤20ppm

<20ppm

CONCLUSION

Comply    with GB/7294-2009

Certificate of Analysis Menadione  Nicotinamide Bisulfite (MNB):

Testing    Item

Standard

Testing    Result

Appearance
Menadione    Nicotinamide Bisulfite

White    Powder

White    Powder

Menadione    Nicotinamide Bisulfite

≥96.0%

96.51%

Menadione    Content

≥44.94%

44.96%

Niacinamide    Content

≥31.%

31.33%

Heavy    metals(as Pb)

≤20ppm

<20PPM

CONCLUSION

Comply    with enterprise internal control standard

Top Quality, China Pure Menadione sodium bisulfite (MSB, Vitamin K3), Menadione Nicotinamide Bisulfite (MNB, Vitamin K3) Powder factory in China; China Menadione sodium bisulfite (MSB, Vitamin K3), Menadione Nicotinamide Bisulfite (MNB, Vitamin K3) Raw Material Suppliers in China. China Menadione sodium bisulfite (MSB, Vitamin K3), Menadione Nicotinamide Bisulfite (MNB, Vitamin K3) API Manufacturers in China. 


If you are looking for the menadione sodium bisulfite cas 130-37-0 or menadione nicotinamide bisulfite 96% cas 73581-79-0 vitamin k3, welcome to contact us. We are one of the leading and professional China manufacturers and suppliers in this field. Competitive price and good after-sale service are available.
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Add: Room 1101, 5th Building, No.168 Shenzhen Road, Qingdao, China
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