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Norfloxacin Nicotinate CAS 118803-81-9 and Norfloxacin Hydrochloride CAS 68077-27-0 and Norfloxacin Lactate CAS 97867-34-0

Norfloxacin Nicotinate CAS 118803-81-9 and Norfloxacin Hydrochloride CAS 68077-27-0 and Norfloxacin Lactate CAS 97867-34-0

Norfloxacin Nicotinate CAS 118803-81-9 and Norfloxacin Hydrochloride CAS 68077-27-0 and Norfloxacin Lactate CAS 97867-34-0 COA—Norfloxacin Nicotinate COA—Norfloxacin Hydrochloride (Norfloxacin Hcl)

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Product Details

Norfloxacin Nicotinate CAS 118803-81-9 and Norfloxacin Hydrochloride CAS 68077-27-0 and Norfloxacin Lactate CAS 97867-34-0                                              Norfloxacin Nicotinate and Norfloxacin Hydrochloride, Norfloxacin lactate.jpg

 

Product

Norfloxacin Nicotinate API, Raw Material

Norfloxacin Hydrochloride API, Raw Material

Norfloxacin Lactate API, Raw Material

Synonyms:

Norfloxacine   Nicotinate

Norfloxacin   Hcl

Norfloxacine   Lactate

Characteristics:

Almost   white slightly yellowish crystallne powder

White   to slightly yellow crystalline powder.

White   powder.

CAS

118803-81-9

68077-27-0

97867-34-0

Assay:

98%   Min

98.5%   Min

99%   Min

Formula:

C22H23FN4O5; 

C16H18FN3O3.C6H5NO2

C16H18FN3O3

C16H18FN3O3·C3H6O3

Structure:

Norfloxacin Nicotinate formula.jpg

Norfloxacin Hydrochloride formula.jpg

Norfloxacin lactate formula.png

Package

25Kg/Fiber DrumCardboard DrumPaper Drum

25Kg/Drum

25Kg/Drum

 

Description:

Norfloxacin Nicotinate, Norfloxacin Hydrochloride, Norfloxacin Lactate are all the salts of Norfloxacin, which is a synthetic fluoroquinolone (fluoroquinolones). They are broad-spectrum antibacterial substances against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacteria.

Norfloxacin Nicotinate, Norfloxacin Hydrochloride, Norfloxacin Lactate  are used to cure bacterial infections. They will kill the sensitive bacteria.

Norfloxacin Nicotinate, Norfloxacin Hydrochloride, Norfloxacin Lactate belong to quinoline carboxylic acids.

The modes of action of Norfloxacin Nicotinate, Norfloxacin Hydrochloride, Norfloxacin Lactate depend on blocking of bacterial DNA replication. This process is done by binding itself to an enzyme called DNA gyrase, which will make the untwisting required to replicate 1 DNA double helix into 2.

 

Norfloxacin Nicotinate, Norfloxacin Hydrochloride, Norfloxacin Lactate Mechanism of Action:

The anti-bactericidal property of Norfloxacin Nicotinate, Norfloxacin Hydrochloride, Norfloxacin Lactate is because of  the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV inhibition. These enzymes are crucially needed for bacterial DNA replication, transcription, repair, and recombination. Norfloxacin Nicotinate, Norfloxacin Hydrochloride, Norfloxacin Lactate is working against both gram-positive and gram-negative bacteria.

The structure of Norfloxacin Nicotinate, Norfloxacin Hydrochloride, Norfloxacin Lactate contributes a lot during this process:

The fluorine atom at the six position increases potency against gram-negative organisms, and the piperazine moiety at the seven position is the reason for anti-pseudomonal activity.

 

As a professional China Norfloxacin Nicotinate, Norfloxacin Hydrochloride Powder supplier and Manufacturer, FENGCHEN GROUP CO., LTD has been supplying and exporting Norfloxacin Lactate Powder raw material from China for almost 10 years. 


Do NOT use Norfloxacin Nicotinate, Norfloxacin Hydrochloride, Norfloxacin Lactate if:

1.There is allergy reaction to any of the above norfloxacin or to any other fluoroquinolone antibiotic (for example, Ciprofloxacin Hcl, etc.)

2.There is inflammation of a tendon or you have a history of ruptured tendon caused by Norfloxacin Nicotinate, Norfloxacin Hydrochloride, Norfloxacin Lactate.

3.There is a myasthenia gravis history.

4.Do not use Norfloxacin Nicotinate, Norfloxacin Hydrochloride, Norfloxacin Lactate together with anti-arrhythmic medicines (For example, procainamide, etc) or Nitrofurantoin.

 

Norfloxacin Nicotinate, Norfloxacin Hydrochloride, Norfloxacin Lactate Side Effects:

Improper use may end in drowsiness, dizziness, light-headedness, etc. These effects may be worsen especially when used together with alcohol, or some certain medicines. Do not drive or perform other possibly unsafe tasks until you know how you react to Norfloxacin Nicotinate, Norfloxacin Hydrochloride, Norfloxacin Lactate.


COA—Norfloxacin Nicotinate

Name   of Product

Norfloxacin Nicotinate

Testing Item

Standard

Result

Appearance

Norfloxacin Nicotinate

Almost white slightly   yellowish crystallne powder

Complies

Identification

Norfloxacin Nicotinate


(1)Malonic   acid/Acetic Anhydride test: Solution shows brownish red colour.

Complies

(2)Sodium   Hydroxide-copper sulphate solution: Blue precipitation

Complies

(3)UV:   Absorption maxima at 271nm, 323nm, 335nm

Complies

(4)IR:   Conforms to the reference spectrum

Complies

Clarity   of solution

(0.5g/10ml   water)

Clear   or not more opalescent than reference suspension II.

Complies

Fluoride

≥   4.0%

4.2%

Related   substances


Spots   of test solution correspond to that of reference solution of nicotinic acid

Complies

Spots   of test solution correspond to that of reference solution of Norfloxacin

Complies

The   intensity of spots of impurities is not greater than that of reference   solution

Complies

Loss   on drying

≤   3.0% (105°C)

2.5%

Assay

(Norfloxacin nicotinate)

≥   98% (On dried basis)

98.3%

 

COA—Norfloxacin Hydrochloride (Norfloxacin Hcl)

Name   of Product

Norfloxacin Hcl

Testing Item

Standard

Result

Appearance

Norfloxacin Hcl

White to slightly   yellow crystalline powder

Complies

Clarity   of solution

Clear   or opacity not more than reference suspension 2

Complies

Fluoride

≥   5.0%

5.2%

Related   Substance

The   spots obtained from the test solution are not more than there, and not more   intensly than the principle spot obtained from the standard solution.

Complies

Loss   on drying

≤   2.0% (105 °C)

0.06%

Residue   on ignition

≤   0.2%

0.02%

Assay

(Norfloxacin Hydrochloride)

≥   98.5% (On dried basis)

99.2%  

 

Top Quality, Pure Norfloxacin Nicotinate, Norfloxacin Hydrochloride, Norfloxacin Lactate Powder;  Norfloxacin Nicotinate, Norfloxacin Hydrochloride, Norfloxacin Lactate Raw Material Suppliers in China. Norfloxacin Nicotinate, Norfloxacin Hydrochloride, Norfloxacin Lactate API Manufacturers. 

Disclaimer
(1) All rights reserved. Reproduction in whole or part expressly forbidden without written permission.
(2) We make every effort to ensure the information presented here is accurate. However, the information above should not be considered as inclusive and shall be used only as a reference.
(3) We make no warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes.

 

Related similar product you may interested:    

Norfloxacin Nicotinate CAS 118803-81-9 And Norfloxacin Hydrochloride CAS 68077-27-0 And Norfloxacin Lactate CAS 97867-34-0

Ofloxacin CAS 82419-36-1 And Levofloxacin Hemihydrate Raw Material, API CAS 138199-71-0

If you are looking for the norfloxacin nicotinate cas 118803-81-9 and norfloxacin hydrochloride cas 68077-27-0 and norfloxacin lactate cas 97867-34-0, welcome to contact us. We are one of the leading and professional China manufacturers and suppliers in this field. Competitive price and good after-sale service are available.

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