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Ivermectin API, Raw Material or Ivermectine 99% EP USP BP CAS 70288-86-7

Ivermectin API, Raw Material or Ivermectine 99% EP USP BP CAS 70288-86-7

Ivermectin API, Raw Material or Ivermectine 99% EP USP BP CAS 70288-86-7 Product Name: Ivermectin Synonyms: Ivermectine, Ivermecti, Ivermectinum CAS: 70288-86-7 Characteristics: White or yellowish-white, crystalline powder. Slightly hygroscopic. Content: Ivermectin (H2B1a + H2B1b): 95.0% ~ 102.0% Formula:...

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Ivermectin API, Raw Material or Ivermectine 99% EP USP BP CAS 70288-86-7                                        Ivermectin API, Raw Material or Ivermectine 99% EP USP BP.jpg

 

Product Name:  Ivermectin API, Raw Material

Synonyms:   Ivermectine, Ivermecti, Ivermectinum

CAS: 70288-86-7

Characteristics:  White or yellowish-white, crystalline powder. Slightly hygroscopic.

Content: Ivermectin (H2B1a + H2B1b): 95.0% ~ 102.0%

Formula: C48H74O14

Ivermectin API, Raw Material or Ivermectine 99% EP USP BP formula and details.jpg

Package: 25Kg/Fiber DrumCardboard DrumPaper Drum; 1Kg/Aluminium Foil Bag 

Description:

Ivermectin is a semisynthetic broad-spectrum anti-parasite, anthelminitic raw material, API. It belongs to milbemycins (potent anti-parasitic agents) which are a group of pentacyclic 16-membered lactone derived from the soil bacterium Streptomyces avermitilis. In some cases (e.g. Milbemycin E), the tetrahydrofuranyl ring is missing. Ivermectin is the most common and popularly seen avermectin. Ivermectin is mainly used to manufacture the formulations which will help to fight against worms. Notably, Ivermectin is not working when treating tapeworm. Most of the times, Ivermectin is taken orally. Ivermectin is effective against worm infestations like strongyloidiasis, ascariasis, etc.

Ivermectin seems to work by paralyzing and then killing the offspring of adult worms. It is also able to slow down adult worm’s reproduction speed. This will make our us have fewer worms in the skin, blood, and eyes.

 

As a professional China Ivermectin Raw Material supplier and Manufacturer, FENGCHEN GROUP CO., LTD has been supplying and exporting Ivermectin API from China for almost 10 years.

Every year, China export about 100Mts Ivermectin raw material to the world market. Fengchen Group’s Ivermectin take at least 10% of the whole market share. 


Usage: Ivermectin is a substance target at infections caused by some parasites.

Ivermectin has an anthelmintic function. It will kill the Ivermectin-sensitive parasites.

For example, head lice, scabies, river blindness, etc are the targeted parasites.

Please avoid direct contact with skin.


Mechanism of Action:

Ivermectin binds selectively and with high affinity to glutamate-gated chloride ion channels in invertebrate muscle and nerve cells of the microfilaria. The above process leads to an increase in the permeability of the cell membrane to chloride ions and results in hyperpolarization of the cell, which will paralyze and kill the parasite.

It is also believed in many researches that Ivermectin raw material API will work as an agonist of the neurotransmitter gamma-aminobutyric acid, then disrupting GABA-mediated central nervous system (CNS) neurosynaptic transmission. Ivermectin may also impair normal intrauterine development of O. volvulus microfilariae and may inhibit their release from the uteri of gravid female worms.

 

Ivermectin Routine of Elimination:

Ivermectin is metabolized in the liver, and ivermectin and/or its metabolites are excreted almost exclusively in the feces over an estimated twelve days, only max one percent of the administered dose excreted in the urine.


Main Indexes— Ivermectin

Product

Ivermectin


Testing Item

Standard

Result

Solubility

Partically   insoluble in water, freely soluble in methylene chloride, soluble in alcohol

Complies

Identification

Ivermectin

1.        IR—Should comply

2.        HPLC—Should comply

Complies

Appearance   of solution

Solution   is clear ≤ BY7

Complies

Specific   Optical Rotation

-17° ~   -20°

-18.5°

Related   Substance

a).Impurity   (1.3<RRT<1.5) ≤ 2.5%

b).Any   other specified impurity     ≤ 1.0%

c).Any   unspecified impurity ≤ 0.20%

d).Total   impurities ≤ 5.0%

a).   2.1%

b).A:0.4%,E:0.2%,H:0.1%,J1:0.4%,J2:0.1%,   F or I(RRT0.86):0.1%,For I(RRT1.56):0.1%

c).RRT1.11:0.05%

d).3.6%  

Ethanol

≤   5.0%

3.7%

Formamide

≤   3.0%

2.3%

Heavy   Metal

≤   0.002%

<0.002%

Moisture

≤   1.0%

0.08%

Sulfated   Ash

≤   0.1%

0.02%

Content   (H2B1a+H2B1b)

95.0%   ~ 102.0% (Ivermectin)

96.8%

H2B1a/(H2B1a+   H2B1b)

≥   90.0%

98.2%

 

Top Quality, Pure Ivermectin Powder;  Ivermectin Raw Material Suppliers in China. Ivermectin API Manufacturers. 

Disclaimer
(1) All rights reserved. Reproduction in whole or part expressly forbidden without written permission.
(2) We make every effort to ensure the information presented here is accurate. However, the information above should not be considered as inclusive and shall be used only as a reference.
(3) We make no warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes.

 

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If you are looking for the Ivermectin API, Raw Material or Ivermectine 99% EP USP BP CAS 70288-86-7, welcome to contact us. We are one of the leading and professional China manufacturers and suppliers in this field. Competitive price and good after-sale service are available.

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Skype: frankrenful2002
E-Mail: frank_feng@fengchengroup.com
Tel: +86-186-7846 1007
WECHAT: +86-18678461007
WHATSAPP: +86-18678461007
Add: Room 1101, 5th Building, No.168 Shenzhen Road, Qingdao, China
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