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Ciprofloxacin Base CAS 85721-33-1 and Ciprofloxacin Lactate CAS 97867-33-9 and Ciprofloxacin Hydrochloride or HCL CAS 86483-48-9

Ciprofloxacin Base CAS 85721-33-1 and Ciprofloxacin Lactate CAS 97867-33-9 and Ciprofloxacin Hydrochloride or HCL CAS 86483-48-9

Ciprofloxacin Base CAS 85721-33-1 and Ciprofloxacin Lactate CAS 97867-33-9 and Ciprofloxacin Hydrochloride or Hcl CAS 86483-48-9 COA—Ciprofloxacin Base COA—Ciprofloxacin Lactate COA—Ciprofloxacin Hydrochloride (Ciprofloxacin Hcl)

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Ciprofloxacin Base CAS 85721-33-1 and Ciprofloxacin Lactate CAS 97867-33-9 and Ciprofloxacin Hydrochloride or Hcl CAS 86483-48-9                                             Ciprofloxacin base, Ciprofloxacin Lactate, Ciprofloxacin hydrochloride picture.jpg

Product   Name:

Ciprofloxacin Base API, Raw Material

Ciprofloxacin Lactate API, Raw Material

Ciprofloxacin Hydrochloride API, Raw Material

Synonyms:

Cipfloxacine,

Ciprofloxacini

Ciprofloxacini Lactate

Ciprofloxacin Hcl,

Ciprofloxacini hydrochloridum

CAS:

85721-33-1

97867-33-9

86483-48-9

or 86393-32-0

Appearance:  

White   crystalline powder

White   powder or crystalline powder

A   pale yellow, crystalline powder, soluble in water

Assay:  

98.0%-102.0%

98.5%   Min

98%  ~ 102%

Formula:

C17H18FN3O3

C20H22FN3O5

C17H18FN3O3,HCl,H2O 

Structure:  

Ciprofloxacin base formula.jpg

Ciprofloxacin Lactate formula.jpg

Ciprofloxacin Lactate hydrochloride, Hcl.gif

Package:

25Kg/Drum

 

Description:

Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride are both slats of Ciprofloxacin. They are all broad-spectrum antimicrobial carboxyfluoroquinolines. They belong to fluoroquinolone class.  Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride have bactericidal ability because they will inhibit enzymes topoisomerase II (DNA gyrase) and topoisomerase IV. There 2 enzymes needed in many bacterial DNA processes, like replication, transcription, repair, strand supercoiling repair, and recombination.

Ciprofloxacin Lactate, Ciprofloxacin Hcl are applied to treat many bacterial-caused infections such as  lung or respiratory tract infections, eye infection, bladder and kidney infections, reproductive tract infections, skin and soft tissue infections and bone and joint infections.

Till now, there is still no cross-resistance between ciprofloxacin and other classes of antimicrobials known to us. We should note that Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride have 100 times higher affinity for bacterial DNA gyrase than for mammalian.

 

As a professional China Cipfloxacin Base,  Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride Raw Material API supplier and Manufacturer, FENGCHEN GROUP CO., LTD has been supplying and exporting Cipfloxacin Base,  Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride Raw Material API from China for almost 10 years.

 

Mechanism of Action:

The way of action of Cipfloxacin Base,  Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride is different from that of other antimicrobial agents like beta-lactams, macrolides, tetracyclines, or aminoglycosides; That is to say, organisms which are resistant to these drugs are still ciprofloxacin. Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride will still work to them.

 

Absorption of Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride:

Ciprofloxacin will be  absorbed from the gastrointestinal tract after oral administration very quickly. The absolute bioavailability is approximately seventy percents with no substantial loss by first pass metabolism.


COA—Ciprofloxacin Base

Name of Product

Ciprofloxacin base


Testing   Item

Standard

Result

Appearance

Ciprofloxacin base

White crystalline powder

White   crystalline powder

Clarity of solution

Ciprofloxacin base

Meet the requirements

Meets the requirements

Loss on drying

≤1.0%

0.2%

Residue on ignition

≤0.2%

0.12%

Heavy metals

≤0.002%

≤0.002%

Sulfate

Chloride

≤0.04%

≤0.04%

<0.04%

<0.02%

Fluoroquinolonic acid

Meet the requirements

Meets the requirements

Ciprofloxacin ethylenediamine anlog

≤0.2%

0.05%

Any other individual impurity

≤0.2%

0.03%

Total impurities

≤0.5%

0.14%

Assay (on the anhydrous basis)

98.0%-102.0%

Ciprofloxacin Base

100.9%

 

COA—Ciprofloxacin Lactate

Name   of Product

Ciprofloxacin Lactate


Testing Item

Standard

Result

Appearance  

Ciprofloxacin Lactate

Almost   white or light yellow crystalline powder; Odorless and bitter, hygroscopicity

Complies

Identification A

Bismuth potassium Iodide solution   test: Solution shows brownish red.

Complies

Identification B

Ciprofloxacin Lactate

UV: Absorption max at 277nm

Complies

Identification C

IR: Conforms to the reference spectrum

Complies

Identification D

Ciprofloxacin Lactate

Lactate Test: Positive

Complies

pH

4.5   ~ 5.5

4.9

Clarity of solution

Clear

Clear

Color   of solution

Absorption   at 430nm ≤0.05

0.03

Fluoride

≥   4.2%

4.5%

Related   Substances

Individual   Impurity ≤0.5%

Total   Impurities ≤1.0%

<   0.5%

<   1.0%

Loss   on drying (60 °C)

≤   6.5%

4.4%

Residual on Ignition

≤   0.1%

0.08%

Heavy   Metal

≤   20ppm

<   20ppm

Assay   (Ciprofloxacin Lactate)

≥   98.5% on dried basis

98.9%

 

COA—Ciprofloxacin Hydrochloride (Ciprofloxacin Hcl)

Name   of Product

Ciprofloxacin Hcl or Ciprofloxacin Hydrochloride


Testing Item

Standard

Result

Characters

Ciprofloxacin Hcl

Faintly   yellowish to light yellow crystals

Complies

Identification   A

IR   Spectrum of sample complies with the reference standard

Complies

Identification   B

Ciprofloxacin Hcl

HPLC:   The retention time of the major peak of the sample solution corresponds to   the one of standard solution, as obtained in the assay

Complies

Identification   C

Show   reaction of chlorides.

Complies

pH

3.0   ~ 4.5

3.7

Water

4.7%   ~ 6.7%

5.3%

Residue   on ignition

≤   0.1%

0.05%

Heavy   metals

≤   20ppm  Ciprofloxacin Hydrochloride

<   20ppm

sulfate

≤   0.04%

<   0.04%

Fluoroquinolonic   acid

≤   0.2%

Complies

Ciprofloxacin   ethylenediamine

≤   0.2%

0.04%

Any   other individual impurity

≤   0.2%

0.05%

Total   impurities

≤   0.5%

0.18%

Ethanol

≤   4000ppm

426ppm

Isoamyl   Alcohol

≤   4000ppm

Not   detected

Assay   (on the anhydrous basis)

98.0%   ~ 102.0%

Ciprofloxacin Hydrochloride (Ciprofloxacin Hcl)

99.4%

 Top Quality, Pure Ciprofloxacin Hydrochloride (Ciprofloxacin Hcl) Powder;  Ciprofloxacin Hydrochloride (Ciprofloxacin Hcl) Raw Material Suppliers in China. Ciprofloxacin Hydrochloride (Ciprofloxacin Hcl) API Manufacturers. 


If you are looking for the ciprofloxacin base cas 85721-33-1 and ciprofloxacin lactate cas 97867-33-9 and ciprofloxacin hydrochloride or hcl cas 86483-48-9, welcome to contact us. We are one of the leading and professional China manufacturers and suppliers in this field. Competitive price and good after-sale service are available.

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Skype: frankrenful2002
E-Mail: frank_feng@fengchengroup.com
Tel: +86-186-7846 1007
WECHAT: +86-18678461007
WHATSAPP: +86-18678461007
Add: Room 1101, 5th Building, No.168 Shenzhen Road, Qingdao, China
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