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Sulfaguanidine Powder API, Raw Material EP, BP, USP CAS 56-67-0

Sulfaguanidine Powder API, Raw Material EP, BP, USP CAS 56-67-0

China Sulfaguanidine Suppliers, China Sulfaguanidine Manufacturers CAS 56-67-0 Product Name: Sulfaguanidine Powder API, Raw Material EP, BP, USP CAS 56-67-0 Synonyms: Sulphaguanidine, Sulfaguine, Sulfaguanidum, Sulfaguanidin CAS Number: 56-67-0 Chemical name: N-(aminoiminomethyl)-4-aminobenzenesulfonamide Characteristics: A white or almost...

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China Sulfaguanidine Suppliers, China Sulfaguanidine Manufacturers CAS 56-67-0

Sulfaguanidine Powder API, Raw Material EP, BP, USP.jpg

Product Name: Sulfaguanidine Powder API, Raw Material EP, BP, USP CAS 56-67-0

Synonyms: Sulphaguanidine, Sulfaguine, Sulfaguanidum, Sulfaguanidin

CAS Number: 56-67-0

Chemical name: N-(aminoiminomethyl)-4-aminobenzenesulfonamide

Characteristics: A white or almost white, fine crystalline powder

Assay: 99.0% ~ 101.0% Sulfaguanidine

Formula: C7H10N4O2S

Structure Formula:

Sulfaguanidine Powder API, Raw Material EP, BP, USP formula.jpg

Package information: 25Kgs/Drum

KEY Words: Sulfaguanidine Powder API, Raw Material EP, BP, USP CAS 56-67-0

Standard: BP, BPV


Description:

Sulfaguanidine is an anti-microbial substance. It is widely proved that Sulfaguanidine has the ability to treat enteric infections.

Sulfaguanidine is a guanidine derivative of sulfanilamide used in veterinary medicines.

Sulfaguanidine is poorly absorbed from the gut but is well suited for the treatment of bacillary dysentery and other enteric infections.

Specifications:

Sulfaguanidine (Sulphaguanidine) Powder API, Raw Material EP, BP, USP is a low-grade sulfa medicine. It is able to inhibit the bacteria. Sulfaguanidine (Sulphaguanidine)  is primarily utilized to produce sulfadiazine, sulfamethazine and other high-grade sulfa drugs.

Sulfaguanidine (Sulphaguanidine) is an intestinal antibacterial sulfonamide proposed for treatment of dysentery and for sterilization of the colon prior to gastrointestinal tract surgery. It an antimicrobial agent from the sulfanilamide group. Mostly, Sulfaguanidine (Sulphaguanidine) will be made into tablet and powder form to treat such intestinal infections as dysentery.

 

Usage:

Sulfaguanidine is a Sulfonamides Antimicrobial anti-inflammatory drugs for the treatment of bacterial bacillary dysentery, bacterial ulcerative enteritis. 


1.
Sulfaguanidine (Sulphaguanidine) belongs to sulfa drugs and used for the treatment of bacillary dysentery and enteritis.
2.
Sulfaguanidine (Sulphaguanidine) may be applied for the treatment of intestinal antibacterial infections like bacterial dysentery enteritis. It will also help to prevent infection before bowel surgery.
3.
Sulfaguanidine (Sulphaguanidine) is always the 1st choice for the treatment of leprosy. It is very suitable for the treatment of various types of leprosy. Sulfaguanidine (Sulphaguanidine) also contribute to alleviate the clinical symptoms. It can generally alleviate the mucosal lesions rapidly with the improvement of skin lesions occurring more slowly, with even slower rate in neuropathy, thereby leading to long course. But Sulfaguanidine (Sulphaguanidine) develops drug resistance easily.

4. In addition, Sulfaguanidine (Sulphaguanidine) can also be applied for treating dermatitis herpetiformis, lupus, psoriasis, foot fungus disease and malaria. Sulfaguanidine (Sulphaguanidine) tablets is the most popularly seen formulation.

 

Production Method of Sulfaguanidine (Sulphaguanidine):

1. the finished product of Sulfaguanidine (Sulphaguanidine) can be produced through the melting of sulfa and guanidine nitrate in the soda and further vacuum condensation.

2. Sulfaguanidine (Sulphaguanidine) can also be alternatively produced from the reaction between acesulfame chloride and guanidine nitrate in the mixed solution of acetone and water in the presence of sodium hydroxide.

3. Use p-nitrobenzenesulfonyl chloride as raw material, go through catalytic hydrogenation reaction to make p-amino benzenesulfonyl chloride and further ammoniation to generate sulfonamides, and then reacted with guanidine nitrate to obtain sulfaguanidine.

 

As a professional China Sulfaguanidine (Sulphaguanidine) Raw Material supplier and Manufacturer in China, FENGCHEN GROUP CO., LTD has been supplying and exporting Sulfaguanidine (Sulphaguanidine) API from China in China for almost 10 years.

 

Drug interactions:

1. The solubility of Sulfaguanidine (Sulphaguanidine) can be enhanced with simultaneous administration of urine alkaline drugs. By this way, the excretion of Sulfaguanidine (Sulphaguanidine) also increases.

2. Sulfaguanidine (Sulphaguanidine) can’t be used in conjuction with 4-aminobenzoic acid, which will replace be absorbed, rather than Sulfaguanidine (Sulphaguanidine), by bacteria and is mutually antagonistic with each other. In addition, Sulfaguanidine (Sulphaguanidine) doesn’t work well together with local anesthetics medicines containing the p-amino-benzoyl group like procaine, tetracaine and so on.

COA of Sulfaguanidine

Name of Product

Sulfaguanidine

Testing Item

Standard

Result

Appearance

White or almost white crystalline or powder

Complies

Identification

(Sulfaguanidine)

Pass IR positive reaction

Conform

Loss on drying

6.0% ~ 8.0%

7.70%

Heavy Metal(ppm)

≤ 20ppm

< 10ppm

Melting Point

189°C ~ 192°C

189.8°C ~ 192.0°C

Chloride

≤ 100ppm

< 100ppm

Sulphate Ash

≤ 0.1%

0.05%

Related Substance

≤ 0.5%

< 0.5%

Assay (Sulfaguanidine)

99.0%  ~ 101.0%

99.67%

Property:

Name: Sulfaguanidine

EINECS: 200-345-9

Sulfaguanidine CAS No.: 57-67-0

Density: 1.62 g/cm3

Sulfaguanidine Solubility: 1g/L in water at 25 °C

Sulfaguanidine Melting Point: 190-193 °C

Formula: C7H10N4O2S

Boiling Point: 488.4 °C at 760 mmHg

Molecular Weight: 214.24

Flash Point: 249.2 °C

Sulfaguanidine Transport Information: UN 3249 6.1/PG 3

Risk Codes: 36/37/38

 

Chemical Property:

Sulfaguanidine (Sulphaguanidine) appears as needle-like crystalline powder with the melting point being 190-193 . 1g of this product can be dissolved in about 1000 ml of water at 25 , dissolved in about 10 ml of water at 100 . It is slightly soluble in ethanol or acetone and easily soluble in dilute hydrochloric acid. Sulfaguanidine (Sulphaguanidine) is odorless and tasteless with its color deepened in the case of light.

 

Other Names: ((4-Aminophenyl)sulfonyl)guanidine; ((p-Aminophenyl)sulfonyl)guanidine; 1-((p-Aminophenyl)sulfonyl)guanidine; 1-Amino-4-(([amino(imino)methyl]amino)sulfonyl)benzene; 1-Sulfanilylguanidine; 4-amino-n-(aminoiminomethyl)-benzenesulfonamid; 4-amino-n-(diaminomethylene)-benzenesulfonamid; 4-Amino-N-(diaminomethylene)benzenesulfonamide

 

Top Quality, China Pure Sulfaguanidine Powder/Substance factory in China; China Sulfaguanidine Raw Material Suppliers in China. China Sulfaguanidine API Manufacturers in China. 


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