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Oxibendazole, Oxibendazol powder Raw Material, API CAS 20559-55-1

Oxibendazole, Oxibendazol powder Raw Material, API CAS 20559-55-1

China Oxibendazole Supplier, China Oxibendazole Manufacturer CAS 20559-55-1 Product Name: Oxibendazole, Oxibendazol powder Raw Material, API CAS 20559-55-1 Synonyms: Oxibendazolum; Oxibendazol; Oxibendasole; Oxbidazole; Oxibendazolo Chemical Name: methyl N-(6-propoxy-1H-benzimidazol-2-yl)carbamate CAS Number: 20559-55-1 Characteristics: White or...

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China Oxibendazole Supplier, China Oxibendazole Manufacturer CAS 20559-55-1

Oxibendazole, Oxibendazol powder Raw Material, API.jpg

Product Name:  Oxibendazole, Oxibendazol powder Raw Material, API

Synonyms:  Oxibendazolum; Oxibendazol; Oxibendasole; Oxbidazole; Oxibendazolo

Chemical Name: methyl N-(6-propoxy-1H-benzimidazol-2-yl)carbamate

CAS Number: 20559-55-1

Characteristics: White or almost white powder, odorless

Assay:  ≥ 98.0% Oxibendazole

KEYWORD: Oxibendazole

Formula: C12H15N3O3

Oxibendazole, Oxibendazol powder Raw Material, API formula.jpg

Package: 25Kgs/Drum

Description & Application:

Oxibendazole is a polymerase inhibitor for the treatment of helminth intestinal infections in human and animal. It can be used for the treatment in infectious and parasitic disease (unspecified) and pediatric indications.

Oxibendazole is a benzimidazole substance which interferes with metabolic pathways. It is used to protect against worms infestations in horses and some domestic pets.

Oxibendazole will significantly reduce the proportion of positive foals.  (about 86%). 

With Chemical Name “Carbamic acid, (5-propoxy-1H-benzimidazol-2-yl)-, metyl ester”,

Oxibendazole, Oxibendazol powder Raw Material, API is a polymerase inhibitor in phase III trials for the treatment of helminth intestinal infections.

Oxibendazole,, Oxibendazol powder Raw Material, API belongs to the class of organic compounds known as 2-benzimidazolylcarbamic acid esters. These are aromatic heteropolycyclic compounds that contain a carbamic acid ester group, which is N-linked to the C2-atom of a benzimidazole moiety.

Oxibendazole, Oxibendazol powder Raw Material, API is a broad-spectrum benzimidazole drug which is widely used to control intestinal parasites in dogs and some other animals.

 

Oxibendazole will heltp to fight against Toxocara canis, Trichuris vulpis,etc.

Highly dosed or used together with diethylcarbamazine, some Side-effects of Oxibendazole may occur. For example, particularly hepatotoxicity.

Suggested right dose should be is fifteen to twenty mg/kg once a day, for two to three days.

 

As a professional China Oxibendazole, Oxibendazol powder Raw Material, API supplier and Manufacturer in China, FENGCHEN GROUP CO., LTD has been supplying and exporting Oxibendazole, Oxibendazol powder Raw Material, API from China in China for almost 10 years.


According to the study Data:

(1) Oxibendazole reduces in the number of strongyle eggs/g (epg) in horse by 82% ~ 89%.

(2) Oxibendazole kills the parasitic worm. 

(3) Oxibendazole reduces faecal worm egg counts (EPG) by 97.6% for Toxocara canis, 95.7% for Trichuris vulpis, 94.6% for Ancylostoma caninum, and 100% for Toxascaris leonine in dogs and cats. 

 

Standard: CPV

Usage: Our Oxibendazole raw material is used to produce Oxibendazole  Tablets and other preparations. Mainly for veterinary use.
Shelf Life: 4 years (48 Months)

 

Oxibendazole Mechanism of Action:

Oxibendazole, Oxibendazol powder Raw Material, API causes degenerative alterations in the tegument and intestinal cells of the worm by binding to the colchicine-sensitive site of tubulin. Therefore, it will inhibit its polymerization or assembly into microtubules. The loss of the cytoplasmic microtubules will result in impaired uptake of glucose by the larval and adult stages of the susceptible parasites, and depletes their glycogen stores. Degenerative changes in the endoplasmic reticulum, the mitochondria of the germinal layer, and the subsequent release of lysosomes result in decreased production of adenosine triphosphate (ATP), which is the energy required for the survival of the helminth. Due to diminished energy production, the parasite is immobilized and eventually dies. The above is the Mechanism of Action of Oxibendazole, Oxibendazol powder Raw Material, API. It will effectively working as expected. 


COA of Oxibendazole

Name    of Product

Oxibendazole    (Oxibendazolum)

Testing Item

Standard

Result

Appearance

White    or almost white powder, odorless

Complies

Identification

Should comply.

Complies

Melting Point

224°C ~ 229°C

224.7°C ~ 225.5°C

Solubility

Very    lightly soluble in methanol and chloroform, practically insoluble in water,    sparingly soluble in acetic acid

Complies

Specific    Optical Rotation

-16°    ~ -19°

-17.5°

Loss    on drying

≤    0.5%

0.22%

Residual on Ignition

≤0.5%

0.1%

Heavy    Metal

≤20ppm

<20ppm

Assay    (Oxibendazole)

≥    98.0%

99.44%

Foreign Names

Oxibendazolum (Latin)

Oxibendazol (German)

 

Top Quality, China Pure Oxibendazole Powder/Substance factory in China; China Oxibendazole Raw Material Supplier in China. China Oxibendazole API Manufacturer in China. 


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If you are looking for the Oxibendazole, Oxibendazol powder Raw Material, API CAS 20559-55-1, welcome to contact us. We are one of the leading and professional China manufacturers and suppliers in this field. Competitive price and good after-sale service are available.
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Skype: frankrenful2002
E-Mail: frank_feng@fengchengroup.com
Tel: +86-186-7846 1007
WECHAT: +86-18678461007
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Add: Room 1101, 5th Building, No.168 Shenzhen Road, Qingdao, China
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