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Cephradine Powder, Compacted and Cephradine with L-Arginine Sterile CAS 38821-53-3

Cephradine Powder, Compacted and Cephradine with L-Arginine Sterile CAS 38821-53-3

Cephradine and Cephradine with L-Arginine Sterile CAS 38821-53-3 Usage: There are 3 forms of Cepharadine. They are Cephradine Powder, Cephradine Compacted, and Cephradine L-Arginine Sterile powder. They are all anti-biotic. Cephradine Powder, Cephradine Compacted are used to make tablets,...

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Cephradine and Cephradine with L-Arginine Sterile CAS 38821-53-3                                              Cephradine Powder, Compacted and Cephradine with L-Arginine Sterile picture.jpg

Product:

Cephradine   Powder

Cephradine   Compacted

Cephradine   L-Arginine Sterile

Synonyms:

Cefradine , Velosef

Appearance:  

White or slightly yellow crystalline powder

CAS   Number:

Cephradine   CAS 38821-53-3

Cephradine   Monohydrate CAS 31828-50-9

Cephradine   Dihydrate CAS 58456-86-3

Assay:  

900µg/mg~1050µg/mg (calculated sum of cephradine   (C16H19N3O4S) and cephalexin (C16H17N3O4S))

Formula:

C16H19N3O4S

Package:

Oral   Grade: 25Kg/Drum      Sterile injection   Grade: 5Kg/Tin

Difference:  

Small   powder to make oral drugs

Larger   powder to make oral drugs

For   injection use

Cephradine Powder, Compacted and Cephradine with L-Arginine Sterile formula.gif


Description:

With a chemical name (6R,7R)-7-((R)-2-Amino-2-(1,4-cyclohexadien-1-yl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, Cephradine belongs to the class of a group of chemicals known as n-acyl-alpha amino acids and derivatives. These compounds contain an alpha amino acid (or a derivative thereof) which bears an acyl group at its terminal nitrogen atom.

Cefradine is the 1st generation of semi-synthetic cephalosporin, antibacterial. It has similar effect with Cephalexin. Just like penicillins, Cefradine is also a kind of beta-lactam antibiotic.

Cefradine will target a lot of Gram-positive bacteria such as Staphylococcus aureus, Staphylococcus epidermidis, pneumococcal disease, hemolytic streptococcus. Also, Cefradine has a bactericidal effect on gram-negative bacteria such as E. coli, Proteus , Klebsiella pneumoniae, Shigella, etc.

 

As a professional China Cepharadine Raw Material supplier and Manufacturer, FENGCHEN GROUP CO., LTD has been supplying and exporting Cepharadine API from China for almost 10 years.

 

Usage and difference of Cepharadine Compacted, Powder and Cephradine Plus L-Arginine sterile.

There are 3 forms of Cepharadine. They are Cephradine Powder, Cephradine Compacted, and Cephradine L-Arginine Sterile powder.  They are all anti-biotic.

Cephradine Powder, Cephradine Compacted are used to make tablets, capsules, and oral medicines.

Cephradine L-Arginine sterile powder is for Injection use. The reason for adding L-Arginine is to make Cephradine more effective and stable.

Cephradine is mainly used for the treatment of sensitive bacterial respiratory and urinary tract, skin and soft tissue infections. Cephradine may also be used to prevent postoperative infections.

 

Mechanism of Action:

Cefradine works by killing or stopping the growth of the bacteria that cause infections.


Usage: There are 3 forms of Cepharadine. They are Cephradine Powder, Cephradine Compacted, and Cephradine L-Arginine Sterile powder.  They are all anti-biotic.

Cephradine Powder, Cephradine Compacted are used to make tablets, capsules, and oral medicines.

Cephradine L-Arginine sterile powder is for Injection use.

COA— Cephradine

Test Items

Specification

Result

Description

White or slightly yellow crystalline powder

Conforms

Solubility

Sparingly soluble in water, practically insoluble   in alcohol

Conforms

Identification

Cefradine

Conforms

Conforms

Appearance of solution

Solutions is not more opalescent than reference   suspension II

Conforms

Clearance of solution

Cefradine

Clear

Clear

Absorbance at 450nm

Not more than 0.2

0.045

PH

Between3.5 and 6.0

4.9

Specific Optical Rotation

Between +80and +90 on anhydrous basis

+85.9

Absorbance at 330nm

Not more than 0.050

0.007

Specific Absorbance at 262nm

Between 215 to 240 on anhydrous basis

226

Particle size

6-14%≥40 mesh, 60-80% between 100-40 mesh, 15-25%≤100   mesh

Confirms

Related substances: 7-ADCA

Cyclohexa-1, 4-dienylglycine

Any other impurity

Not more than 1.0% by TLC

Not more than 1.0% by TLC

Not more than 1.0% by TLC

Confirms

Confirms

Confirms

Water

Not more than 6.0%

4.5%

Cephalexin content

Not more than 5.0%

1.0%

Sulfated Ash

Not more than 0.20%

0.06%

Loose Density

0.62-0.68 GR/ML

0.65GR/ML

Tapped Density

≥0.85 GR/ML

Confirms

Assay Cefradine

Not less than 90.0% w/w as cefradine on anhydrous   basis by HPLC

Between 95.0% and 102.0% w/w on anhydrous basis by   HPLC (sum of the percentage contents of cephradine)

96.3%

 

99.2%

 

Top Quality, Pure Cefradine Powder;  Cefradine Raw Material Suppliers in China. Cefradine API Manufacturers. 


If you are looking for the Cephradine Powder, Compacted and Cephradine with L-Arginine Sterile CAS 38821-53-3, welcome to contact us. We are one of the leading and professional China manufacturers and suppliers in this field. Competitive price and good after-sale service are available.

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Skype: frankrenful2002
E-Mail: frank_feng@fengchengroup.com
Tel: +86-186-7846 1007
WECHAT: +86-18678461007
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Add: Room 1101, 5th Building, No.168 Shenzhen Road, Qingdao, China
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