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Ceftriaxone Sodium Salt Sterile for injection grade CAS 74578-69-1

Ceftriaxone Sodium Salt Sterile for injection grade CAS 74578-69-1

Ceftriaxone Sodium Salt Sterile CAS 74578-69-1 Product Name: Ceftriaxone Sodium Salt Sterile Synonyms: Ceftriaxonum natricum CAS Number: 74578-69-1 Characteristics: White or yellowish-white crystalline powder Assay and Potency: (1)USP & BP Standard: Minimum 795µg/mg of ceftriaxone (C 18 H 18...

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Ceftriaxone Sodium Salt Sterile for injection Grade CAS 74578-69-1                                              Ceftriaxone Sodium Salt Sterile for injection grade picture.jpg

Product Name:  Ceftriaxone Sodium Salt Sterile for injection grade

Synonyms:  Ceftriaxonum natricum

CAS Number: 74578-69-1

Characteristics:  White or yellowish-white crystalline powder

Assay and Potency: 

(1)USP & BP Standard: Minimum 795µg/mg of ceftriaxone (C18H18N8O7S3)

(2) EP Standard: 96%~102%

Formula: C18H16N8Na2O7S3·3½H2O

Ceftriaxone Sodium Salt Sterile for injection grade formula.gif 

Package:  6Kgs/Sterile Tin, 2 Tins/Ctn;  10Kg/Tin;  5Kg/Tin, 2Tins/Ctn

Description:

Ceftriaxone Sodium is the sodium salt of Ceftriaxone, which belongs a group of antibiotics known named cephalosporins. Ceftriaxone Sodium is usually prescribed by our doctor to prevent or treat certain bacteria-caused infections. 

Ceftriaxone Sodium is widely applied for infections like respiratory tract infections, urinary tract infections, and some other infections.  It is also working when fight against gonorrhea, septicemia, especially popularly used in coronary bypass operations.  One of the advantages of Ceftriaxone Sodium is that it has a relative longer half-life. The dosage of  Ceftriaxone Sodium  should be decreased if use it to the patients with renal impairment. Ceftriaxone Sodium one of the few cephalosporins which will be eliminated primarily by the liver.

Ceftriaxone Sodium is a 3rd generation cephalosporin with a  broad-spectrum activity against Gram-positive bacteria and expanded Gram-negative coverage.

 By injection, Ceftriaxone Sodium can only be given into muscle or vein.

Usage: To make Ceftriaxone Sodium Salt Sterile injections

Ceftriaxone Sodium is often used (in combination, but not direct, with macrolide and/or aminoglycoside antibiotics) for the treatment of community-acquired or mild to moderate health care-associated pneumonia. Ceftriaxone Sodium is also an alternative for treating bacterial meningitis. In pediatrics, Ceftriaxone Sodium is usually used in febrile infants between four to eight weeks old

 Fengchen Group is a leading supplier of Ceftriaxone Sodium Salt Sterile Powder from China. We specialize in wholesale and bulk amounts, ensuring all our clients have the right supplier of Ceftriaxone Sodium Salt Sterile powder when they need it. When you are going to buy or purchase Ceftriaxone Sodium Salt Sterile Powder, please turn to Fengchen Group.

 Notice:

-Ceftriaxone Sodium  is not right choice the infant has hyperbilirubinemia. It competes with bilirubin for binding sites on albumin.

-Ceftriaxone Sodium  should be used with caution in combined renal and hepatic failure.

 

ADVERSE REACTIONS or Side effects of Ceftriaxone Sodium:

Diarrhea, pseudomembranous colitis, vomiting, Haemolysis and Skin rash are reported side effects of Ceftriaxone Sodium. There can be also conditions like Eosinophilia, thrombocytosis, Hypoprothrombinaemia, leukopenia, increase in bleeding times. Very rare, Biliary sludging

 Mechanism of Action: 

Ceftriaxone sodium will interfere with bacteria cell walls synthesis. Eventually will lead to the death of bacteria.  

 

Drug Interactions:

Ceftriaxone sodium can interact with a number of medicines, which include, but are not limited to Warfarin, Sulfinpyrazone, Probenecid, etc.

RS of Ceftriaxone Sodium:

Ceftriaxone Sodium Salt Sterile for injection grade spectrum.jpg

COA—Ceftriaxone Sodium

Testing Item

Standard

Result

Appearance: Ceftriaxone Sodium

White   or yellowish-white crystalline powder

Complies

Crystallinity

the particles show birefringence (interference colors) and   extinction positions when the microscope stage is revolved.

Complies

Identification: Ceftriaxone Sodium

Infrared-spectrometry: The spectrum of the substance to be   examined and of a qualified reference standard are comparable to the position   of the absorption bands

Complies

HPLC: The retention time of major peak in the chromatogram of   test solution correspond to this of standard solution

Complies


Test for solution: It responds to the reaction of sodium

Complies


Visible foreign matter

Essential free

Absent

pH

Ceftriaxone Sodium

6.0 ~ 8.0

7.06

Absorbance(430nm)

<0.1

0.05

Related Substances

Deacetylcefotaxime lactone: ≤ 0.5%;
  7-aminocephalosporanic acid: ≤ 0.5%;
  Ceftriazone triazine analog: ≤ 1.0%;
  Ceftriazone benzothiazolyl oxime: ≤ 0.2%;
  Deacyl ceftriaxone: ≤ 0.5%;
  Ceftriaxone 3-ene isomer: ≤ 0.3%
  Ceftriaone E-isomer: ≤ 0.5%;
  Any individual unspecified impurity: ≤ 0.2%;

Total impurities: ≤ 2.5%

0.008%
  Absent
  0.02%
  Absent
  0.007%
  Absent
  Absent
  0.006%
  0.05%

Water

8.0%   ~ 11.0%

9.46%

Residual Solvents

Triethylamine ≤ 0.02%

N,N-dimethylaniline ≤ 0.002%

2-ethylhexanoic acid ≤ 0.8%

Isoproranol ≤ 0.5%

Methanol ≤ 0.3%

Acetone ≤ 0.5%

Methylene chloride ≤ 0.06%

Ethyl acetate ≤ 0.5%

Ethanol ≤ 0.5%

Absent

Absent

Absent

0.005%

Absent

0.002%

None

0.0003%

0.001%

Bulk   Density

>   0.5g/ml

0.56   g/ml

Bacterial   Endotoxins

≤   0.20 USP Endotoxin Unit/mg of Ceftriaxone

Complies

Pyrogens

Non-Pyrogenic

Non-Pyrogenic

Sterility   test

Should   be sterile

Sterile

Assay

(Ceftriaxone Sodium)

≥   795ug/mg of Ceftriaxone (Dried basis)

925.6ug/mg

 

Top Quality, Pure Ceftriaxone Sodium Powder;  Ceftriaxone Sodium Raw Material Suppliers in China. Ceftriaxone Sodium API Manufacturers. 


If you are looking for the Ceftriaxone Sodium Salt Sterile for injection grade CAS 74578-69-1, welcome to contact us. We are one of the leading and professional China manufacturers and suppliers in this field. Competitive price and good after-sale service are available.

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Add: Room 1101, 5th Building, No.168 Shenzhen Road, Qingdao, China
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