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Ceftizoxime Sodium Salt Powder BP, EP, USP (Sterile) CAS 64485-93-4

Ceftizoxime Sodium Salt Powder BP, EP, USP (Sterile) CAS 64485-93-4

Ceftizoxime Sodium Salt Powder BP, EP, USP (Sterile) CAS 64485-93-4 Product Name: Ceftizoxime Sodium Salt Powder Synonyms: Ceftizoxime Na, Ceftizoxime natrium, CAS Number: 64485-93-4 Characteristics: White to slightly yellowish crystal or powder Assay: 916ug/mg ~964ug/mg Ceftizoxime Sodium...

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Ceftizoxime Sodium Salt Powder BP, EP, USP (Sterile) CAS 64485-93-4

Ceftizoxime Sodium Salt Powder BP, EP, USP (Sterile).jpg

Product Name: Ceftizoxime Sodium Salt Powder API, Raw Material

Synonyms: Ceftizoxime Na, Ceftizoxime natrium,

CAS Number: 64485-93-4

Characteristics:  White to slightly yellowish crystal or powder

Assay: 916ug/mg ~964ug/mg Ceftizoxime Sodium

Formula: C16H16N5NaO7S2

Structure:

Ceftizoxime Sodium Salt Powder BP, EP, USP (Sterile) formula.jpg

Ceftizoxime Sodium Salt Powder BP, EP, USP (Sterile) formula-2.jpg

KEY Words: Ceftizoxime Sodium, Ceftizoxime Sodium Salt, Ceftizoxime Sodium Powder,

Ceftizoxime Sodium USP, Ceftizoxime Sodium EP Powder API, Raw Material

Package: 6Kgs/Aluminium Container; 2 Containers/Carton Box

Storage: Store in a dry protected form light place at room temperature.

Stability: Stable. Incompatible with strong oxidizing agents.

Description:

Ceftizoxime Sodium is the Na salt of Ceftizoxime. It belongs to third generation cephalosporins.

With broad spectrum cephalosporin antibiotic, Ceftizoxime Sodium Salt is a sterile, semi-synthetic, beta¬-lactamase resistant substance which be administered intravenously or by suppository.

The advantage of Ceftizoxime Sodium is highly resistant to a broad spectrum of beta-lactamases and it is active against a lot of aerobic and anaerobic gram-positive and gram-negative organisms. Ceftizoxime Sodium has very few side effects. It is considered to be a safe and effective drug in aged patients and patients with hematologic problems.

Ceftizoxime Sodium is not metabolized, and it is excreted virtually unchanged by our kidneys in 1 day. This will make sure a high urinary concentration.

Ceftizoxime Sodium Salt is indicated for treatment of infections such as 1. Septicemia, 2. Urinary Tract Infections, 3. Pelvic Inflammatory Disease, 4. Skin and Skin Structure Infections, 5. Lower Respiratory Tract Infections, 6. Gonorrhea including uncomplicated cervical and urethral gonorrhea

Mechanism of Action of Ceftizoxime Sodium:

With an extended spectrum of activity against many harmful micro living, Ceftizoxime Sodium has excellent beta-lactamase stability. It binds to specific penicillin-binding proteins which located inside the bacterial cell wall.  Ceftizoxime Sodium inhibits the 3rd and last stage of bacterial cell wall synthesis. This is the mechanism of king bacterial.

As a professional China Sterile Ceftizoxime Sodium Salt Powder raw material API USP, BP, EP supplier and Manufacturer, FENGCHEN GROUP CO., LTD has been supplying and exporting Sterile Ceftizoxime Sodium Salt Powder raw material API USP, BP, EP from China for almost 10 years. 

Being a very broad-pectrum antibiotic, Ceftizoxime Sodium Salt should be administrated with caution in persons with a history of gastrointestinal disease, particularly colitis.

Although Ceftizoxime Sodium Salt has not been shown to produce any alteration in renal function, renal status should be evaluated, especially in seriously ill patients receiving maximum dose therapy. Prolonged use of Ceftizoxime Sodium Salt may cause a overgrowth of nonsusceptible organisms. Appropriate measures should be taken if super-infection happens after the usage. Careful observation is very important.

Ceftizoxime Sodium without a good proof is unlikely to provide benefit to our patient. There is a big risk of the drug-resistant, which is never what we expected.

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Ceftizoxime Sodium BP USP EP Powder API, Raw Material

CAS Registry Number 68401-82-1

Synonyms: (6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt

Molecular Formula: C13H12N5NaO5S2

Molecular Weight: 405.38

As a third-generation cephalosporin antibiotic, Ceftizoxime Sodium EP Powder API, Raw Material is able to help treat the infections. It will be either injected into a large muscle or added to an intravenous fluid formulation which will drip through a needle or catheter for about half an hour, 2-3 times per day.

Ceftizoxime Sodium EP Powder API, Raw Material will eliminate bacteria which will cause several types of infections, such as lung, bone, skin, stomach, joint, blood, and urinary tract infections. In some occasions, Ceftizoxime Sodium EP Powder API, Raw Material will be prescribed for other application or indications.

 

Indications:

Ceftizoxime Sodium EP Powder API, Raw Material is prescribed for treating infections due to susceptible bacterial strains (does not include Pseudomonas aeruginosa), mainly in the respiratory system, genitourinary system, skin, joint, and bone.

Contraindications:

Known sensitivity to Ceftizoxime Sodium EP Powder API, Raw Material prohibits its use. By the way, it should also be very careful for those who are allergic to penicillin.

 

Side effects:

Ceftizoxime Sodium EP Powder API, Raw Material might lead to the following side effects:

Vomiting, diarrhea, upset stomach, stomach pain.

Rash, itching, hives, breath difficulty or unusual bleeding or bruising, neutropenia, leukopenia, thrombocytopenia, and pain at the injection site may also happen after taken Ceftizoxime Sodium EP Powder API, Raw Material.

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COA of Ceftizoxime Sodium:


Testing Item

Standard

Result

Appearance
 Ceftizoxime    Sodium

White    to slightly yellowish crystal or powder

Almost white powder

Solubility

Freely soluble in water; sparingly soluble in    ethanol

Conforms

Identification
 Ceftizoxime    Sodium Salt

Infrared-Spectrometry: both spectra    exhibitsimilar intensities of absorption at the samewave numbers

Complies

It    responds to the qualitative test of sodium salt

Complies

The    chromatogram of the Assay obtained asdirected in the Assay exhibits a major    peak for cefotaxime, the retention time of which corresponds to that    exhibited in the chromatogram of the Standard preparation obtained as    directed in the Assay

Complies

Specific    Rotation

+58°    ~ +64°

+60.59°

pH

4.5    ~ 6.5

5.61

Clarity of Solution

Clear

Clear

Color of Solution

Absorbance    ≤ 0.20

0.046

Loss on drying

≤    3.0%

2.01%

Particulate Matters
 ≥    10um

≤    3000particles/g

80 particles/g

Particulate Matters
 ≥25um

≤    300particles/g

6 particles/g

Any Indivifual Impurity

≤    1.0%

0.16%

Total    Impurities

≤    3.0%

1.61%

Visible foreign matters

Essentially free from

Essentially free from

Bacterial    Endotoxin

≤    0.025Eu/mg

< 0.025Eu/mg

Sterility

Sterile

Sterile

Triethylamine

≤    0.02%

0.004%

Tetramethylene    Oxide

≤    0.072%

Undetectable

Isopropanol

≤    0.5%

Undetectable

Methanol

≤    0.3%

Undetectable

Acetone

≤    0.5%

0.34%

Methylene    Chloride

≤    0.06%

Undetectable

Ethyl    Acetate

≤    0.5%

Undetectable

Ethanol

≤    0.5%

0.02%

Assay
 Ceftizoxime    Sodium

916ug/mg    ~964ug/mg
 Anhydrous Basis

953.3ug/mg

Top Quality, China Pure Ceftizoxime Sodium Powder/Substance Factory in China; China Ceftizoxime Sodium Salt Raw Material Suppliers in China. China Ceftizoxime Sodium Salt API Manufacturers in China.



If you are looking for the ceftizoxime sodium salt powder bp, ep, usp (sterile) cas 64485-93-4, welcome to contact us. We are one of the leading and professional China manufacturers and suppliers in this field. Competitive price and good after-sale service are available.
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