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Cefotaxime Sodium Salt Sterile for injection grade CAS 64485-93-4

Cefotaxime Sodium Salt Sterile for injection grade CAS 64485-93-4

Cefotaxime Sodium Salt Sterile for injection grade CAS 64485-93-4 Product Name: Cefotaxime Sodium Salt Sterile Synonyms: Cefotaximum Natricum CAS Number: 64485-93-4 Characteristics: A white or slightly yellow powder Content: (1) USP Specification: 916µg/mg ~ 964µg/mg, calculate cefotaxime (C 16 H 17 N 5 O 7 S 2 )...

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Cefotaxime Sodium Salt Sterile for injection grade CAS 64485-93-4                                              Cefotaxime Sodium Salt Sterile for injection grade picture.jpg

Product Name:  Cefotaxime Sodium Salt Sterile

Synonyms:  Cefotaximum Natricum

CAS Number: 64485-93-4

Characteristics:  A white or slightly yellow powder

Content: 

(1)   USP Specification: 916µg/mg ~ 964µg/mg, calculate cefotaxime (C16H17N5O7S2)

(2)   BP and EP Specification: 96%~101%

Formula: C16H16N5NaO7S2

Cefotaxime Sodium Salt Sterile for injection grade formula.gif

Package:  5KG/TIN,2TIN/CARTON

Storage: Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat

Shelf Life: 5 years if sealed and store away from direct sun light. 

Description:

Cefotaxime Sodium is the sodium salt form of cefotaxime. It is a beta-lactam, 3rd generation cephalosporin antibiotic with bactericidal activity. The detailed chemical name is Sodium (6R,7R)-7-[2-(2-amino-4-thiazolyl)glyoxylamido]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 72-(Z)-(O-methyloxime),acetate (ester).

Cefotaxime Sodium is an antibiotic used to treat a number of bacterial infections. Specifically workable when treat infections in respiratory tract, urinary tract. Compared with 1st and 2nd generation cephalosporins, cefotaxime sodium salt sterile is more active against gram-negative bacteria and less active against gram-positive bacteria.

Usage: Cefotaxime Sodium Salt Sterile is used to make injections. Its main ability is to kill bacterial by break the cell walls. Then the bacterial dies. Please follow usage dosage and instructions.  


Mechanism of Action:

Cefotaxime Sodium Salt Sterile binds to and inactivates penicillin-binding proteins, which is located on bacterial cell wall’s  inner membrane. This action will weaken bacterial cell wall and finally lead to bacterial cell lysis.

 

Cefotaxime Sodium Side Effects:

Common adverse reactions of Cefotaxime Sodium reported are:

inflammation at the site of injection, nausea, allergic reactions.

Cefotaxime Sodium is not suggested to be used to people who has a history of naphylaxis to a penicillin. One of the advantage of Cefotaxime Sodium is that it is relatively safe for use during pregnancy and breastfeeding. 


COA—Cefotaxime Sodium

TEST

REFERENCE

RESULTS

Description

Cefotaxime Sodium

A   white to slight yellow powder or crystalline powder. Freely soluble in water,   sparingly soluble in methanol insoluble in ethanol or chloroform

Complies

Specific   optical rotation

+55°~   +64°

+60°

Specific   absorbance

360~390

381

Identification

Cefotaxime Sodium

The   HPLC RT should correspond to that of reference standard

Complies

The   IR spectrum should match with that of reference atandard

Complies

Yields   the flame reaction of sodium salts

Complies

PH

4.5~6.5

6.1

Clarity   of solution

≤   0.5 #

≤   0.25#

Light   absorption

≤   0.20

≤ 0.06

Related   substances

Individual   Impurity not more than 1.0%; Total impurities not more than 3.0%

Complies

Particulate   matter

≥   10um  ≤6000/g

≥   25um   ≤600/g 

110/g

16/g

Cefotaxime   polymer

≤   0.5%

0.07%

Visible   parlicles

≤ 5   /3g

Complies

Sterility

Should   be sterile

sterile

Bacterial   endotoxins

<   0.050 EU/mg

Complies

Water

≤   6.0%

1.0%

2-Ethylhexanoic   acid

≤   0.5%

0%

Residual   solvents

Methanol   ≤ 0.3%

Ethanol   ≤ 0.5%

Acctone   ≤0.5%

Complies

Complies

Complies

Specific   volume

Report   the result

3.0ml/g

Assay   

Not   less than 86.0% of Cefuroxime on the anhydrous basis

95.9%

Assay   

96%   ~ 102% Cefotaxime Sodium

99.9%

Top Quality, Pure Cefotaxime Sodium Powder;  Cefotaxime Sodium Raw Material Suppliers in China. Cefotaxime Sodium API Manufacturers. 


If you are looking for the Cefotaxime Sodium Salt Sterile for injection grade CAS 64485-93-4, welcome to contact us. We are one of the leading and professional China manufacturers and suppliers in this field. Competitive price and good after-sale service are available.

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