Cefazolin Sodium CAS 27164-46-1
Cefazolin Sodium CAS 27164-46-1 Product Name: Cefazolin Sodium Synonyms: Cefazolinum natricum, Cefazoline Sodium CAS Number: 27164-46-1 Characteristics: White or almost white very hygroscopic powder. Content: BP, EP Standard: 95%~102% USP Standard: 89.1%~110.1% Formula: C 14 H 13 N 8 NaO 4 S 3...
Cefazolin Sodium CAS 27164-46-1
Product Name: Cefazolin Sodium
Synonyms: Cefazolinum natricum, Cefazoline Sodium
CAS Number: 27164-46-1
Characteristics: White or almost white very hygroscopic powder.
BP, EP Standard: 95%~102%
USP Standard: 89.1%~110.1%
(6R)-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7R-[[2-(1H-tetrazol-1-yl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, monosodium salt, in common name Cefazolin Sodium, (also known as cefazoline or cephazolin) is a semi-synthetic 1st generation cephalosporin for parenteral administration. Cefazolin sodium has a broad-spectrum antibiotic action ability targeting bacterial cell wall. It will attain a high serum level and will be excreted very quickly via the urine.
Infections happened to many different parts of our body can be treated with Cefazolin Sodium. This drug is also applied before some specific types of surgery for infection prevention. Cefazolin Sodium works by killing bacteria or preventing bacteria growth. However, Cefazolin Sodium is not workable for treating virus infections like colds, flu, etc.
Usage: Cefazolin Sodium is the sodium salt of Cefazolin. It belongs to cephalosporin anti-biotic against infections. Cefazolin Sodium also have some infection preventing function. It is mainly made into Cefazolin Sodium Injection.
The main indication of Cefazolin Sodium is skin bacterial infections. It is not just limited to this. Cefazolin Sodium is also widely applied to treat moderately severe bacterial infections related to lung, bone, joint, stomach, blood, heart valve, and urinary tract. To be more specific, Cefazolin Sodium is clinically effective when fighting against infections caused by staphylococci and streptococci species. Cefazolin Sodium is also popularly applied in surgical prophylaxis; There is also a lot of cases when Cefazolin Sodium is used together with metronidazole.
Cefazolin Sodium Mechanism of Action:
The same as 1st generation cephalosporins.
Cefazolin Sodium Absorption:
Cefazolin Sodium will not be absorbed from GI tract. It should be administered parenterally. It only take about one or two hours to reach peak serum concentrations after intramuscular injection.
Cefazolin Sodium’s Routine of Elimination:
Cefazolin Sodium’s concentration will be very low in s in nursing mother’s milk. It will be excreted unchanged in the urine. In the first 6 hours, about sixty percents of Cefazolin Sodium is excreted in the urine. It will reach seventy percent to eighty percents in about 1 day.
Market of Cefazolin Sodium:
Uzbekistan, Slovenia, Belarus, Russia, Vietnam, Thailand, Malaysia, Pakistan, Lithuania, etc.
WHITE OR ALMOST WHITE
SPECIFIC OPTICAL ROTATION
-15°∽ - 24°
260 ∽ 300
4.0 ∽ 6.0
CLARITY OF SOLUTION
COLOR OF SOLUTION
≤ 1.0% (SINGLE)
≤ 3.5% (TOTAL)
≤ 0.0020 %
(AS ANHYDROUS SUBSTANCE)
95.0% ∽ 101.0% (ASSAY OF
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