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Trihexyphenidyl Hcl or Benzhexol hydrochloride CAS 52-49-3 Powder API, Raw Material

Trihexyphenidyl Hcl or Benzhexol hydrochloride CAS 52-49-3 Powder API, Raw Material

Trihexyphenidyl Hcl or Benzhexol hydrochloride CAS 52-49-3 Powder API, Raw Material Product Name: Trihexyphenidyl Hcl or Benzhexol hydrochloride Synonyms: Trihexyphenidyl Hydrochloride, Benzhexol Hcl Chemical Name: 1-Piperidinepropanol, α-cyclohexyl-α-phenyl-, hydrochloride; tremin; CAS Number: 52-49-3 Characteristics:...

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Trihexyphenidyl Hcl or Benzhexol hydrochloride CAS 52-49-3

Trihexyphenidyl Hcl or Benzhexol hydrochloride powder raw material, API.png

Product Name: Trihexyphenidyl Hcl or Benzhexol hydrochloride

Synonyms: Trihexyphenidyl Hydrochloride, Benzhexol Hcl

Chemical Name: 1-Piperidinepropanol, α-cyclohexyl-α-phenyl-, hydrochloride;

tremin;

CAS Number: 52-49-3

Characteristics: White crystalline odorless powder. 

Assay:  98.0% Min Trihexyphenidyl Hydrochloride

Formula:   C20H32ClNO

Structure Formula: 

Trihexyphenidyl Hcl or Benzhexol hydrochloride formula.png

Package information: 25Kg/Fiber DrumCardboard DrumPaper Drum
KEY Words: Trihexyphenidyl Hcl, Trihexyphenidyl Hydrochloride, Benzhexol hydrochloride, Benzhexol Hcl Powder API, Raw Material

Solubility: Slightly soluble in water; sparingly soluble in alcohol and in dichloromethane

Description:
Trihexyphenidyl Hcl is also spells Trihexyphenidyl Hydrochloride, Benzhexol hydrochloride, Benzhexol Hcl.  
It is well-known used to treat parkinsonism and the extrapyramidal side effects of anti-psychotic drugs. Trihexyphenidyl Hcl or Trihexyphenidyl Hydrochloride is a muscarinic antagonist. It qualitatively resembles the belladonna alkaloids in its pharmacological actions along with side effects.
Benzhexol hydrochloride or Benzhexol Hcl will help fight against extrapyramidal movement disorders and as an antispasmodic.
Trihexyphenidyl Hcl or Trihexyphenidyl Hydrochloride is an oral anticholinergic agent used predominantly in the symptomatic therapy of Parkinson disease and movement disorders.  
It is not reportedly been associated with serum enzyme elevations during treatment, but Benzhexol hydrochloride or Benzhexol Hcl has been implicated in rare cases of acute liver injury.

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Trihexyphenidyl Hcl or Benzhexol hydrochloride Powder API, Raw Material is indicated as an adjunct in the treatment of all forms of parkinsonism (postencephalitic, arteriosclerotic, and idiopathic). Trihexyphenidyl Hcl or Benzhexol hydrochloride Powder API, Raw Material is often applied as adjuvant therapy when treating these forms of parkinsonism in conjunction with levodopa. More over, Trihexyphenidyl Hcl or Benzhexol hydrochloride Powder API, Raw Material is indicated for the control of extrapyramidal disorders caused by central nervous system medicines like the dibenzoxazepines, phenothiazines, thioxanthenes, and butyrophenones.

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Uses:
Trihexyphenidyl Hcl or Trihexyphenidyl Hydrochloride belongs to anticholinergics. Benzhexol hydrochloride or Benzhexol Hcl works by blocking a certain natural substance (acetylcholine). All of these helps decrease muscle sweating, stiffness.  And helps improve walking ability in people with Parkinson's disease.
Trihexyphenidyl Hcl or Trihexyphenidyl Hydrochloride can stop severe muscle spasms of the neck back, and eyes. Benzhexol hydrochloride or Benzhexol Hcl will also decrease some side effects like muscle stiffness or rigidit.
NOTE: Trihexyphenidyl Hcl or Trihexyphenidyl Hydrochloride is not helpful when you want to treatmovement problems caused by tardive dyskinesia.  Benzhexol hydrochloride or Benzhexol Hcl  may worsen them, please pay special attention to this condition.

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Pharmacokinetics:

Trihexyphenidyl Hcl or Benzhexol hydrochloride Powder API, Raw Material can be well absorbed from the gastrointestinal tract and has been stated to exert an effect within 60 minutes of an oral dose.

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NOTES and Precautions: Concomitant Use with Levodopa

When Trihexyphenidyl Hcl or Benzhexol hydrochloride Powder API, Raw Material is used concomitantly with levodopa, the usual dose of each should be reduced. Careful adjustment is crucially needed. These adjustments differs depending on adverse reactions and degree of symptom control. An Trihexyphenidyl Hcl or Benzhexol hydrochloride Powder API, Raw Material dosage of  3  to 6 mg per day, in divided doses, is normally already enough.

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Main indexes of Trihexyphenidyl Hcl or Benzhexol hydrochloride:

ANALYSIS

SPECIFICATION

RESULTS

Appearance
Benzhexol Hcl

White crystalline odorless powder.
     Benzhexol hydrochloride

Complies

Identification
Benzhexol Hcl

1.Melting Point: 112C-116C
     2.IR spectrum should comply with standard
     3.Positive reaction

112.4C-115.1C
     Complies
     Complies

Propiophenone A

≤0.5%

0.39%

PH

5.0~6.0

5.7

Loss on Drying

≤0.5%

0.04%

Residue on Ignition

≤0.1%

0.07%

Assay
Trihexyphenidyl Hcl

98.0% Min
     Trihexyphenidyl Hydrochloride

99.73%

Top Quality, China Pure Trihexyphenidyl Hcl, Trihexyphenidyl Hydrochloride, Benzhexol hydrochloride, Benzhexol Hcl Powder factory in China; China Trihexyphenidyl Hcl, Trihexyphenidyl Hydrochloride Raw Material Suppliers in China. China Benzhexol hydrochloride, Benzhexol Hcl API Manufacturers in China. 


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