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Levamisole Base CAS 14769-73-4 Levamisole Hydrochloride API, Raw Material Powder CAS 16595-80-5

Levamisole Base CAS 14769-73-4 Levamisole Hydrochloride API, Raw Material Powder CAS 16595-80-5

Levamisole Base CAS 14769-73-4 Levamisole Hydrochloride API, Raw Material Powder CAS 16595-80-5 Keywords: Levamisole Hcl, Levamisole Hydrochloride, Levamisole Base, Levamisole -Description of Levamisole Base: In immunosuppressed states, Levamisole may restore immune function by: 1) stimulating antibody formation, 2)...

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Product Details

Levamisole Base CAS 14769-73-4 Levamisole Hydrochloride CAS 16595-80-5

Levamisole Base, Levamisole Hydrochloride API, Raw Material Powder.png

Product Name:

Levamisole Base

Levamisole Hydrochloride

Synonyms:

 Levamisol

Levamisole Hcl

Characteristics:

Almost white crystalline power

A white or almost white crystalline power.

CAS Number:

14769-73-4

16595-80-5

Formula:

C11H12N2S

C11H13ClN2S

Structure:

Levamisole Base, Levamisole Hydrochloride API, Raw Material Powder formula.png

Levamisole Base, Levamisole Hydrochloride API, Raw Material Powder structure.png

Transportation:

UN 2811

UN 2811

Package:

25Kgs/drum

25Kgs/Drum

Keywords: Levamisole Hcl, Levamisole Hydrochloride, Levamisole Base, Levamisole API Raw Material Powder

General information:

There are 2 common forms of Levamisole, the free base and the hydrochloride salt. The molecular formula of the Levamisole base is C11H12N2S having a molecular weight of 204.3. Its melting point is 60-61.5 degrees Celsius (140-143 oF) and is not soluble in water. Levamisole Hydrochloride salt is soluble in water and melts at 228-230 oC (442-446 oF). Other chemical names include (S)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole; and (-)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole. The Chemical Abstract Service (CAS) number of the free base is 14769-73-4 and the hydrochloride salt is 16595-80-5.


 As a professional China Levamisole Hcl, Levamisole Hydrochloride, Levamisole Base, Levamisole API, Raw Material Powder supplier and Manufacturer in China, FENGCHEN GROUP CO., LTD has been supplying and exporting Levamisole Hcl, Levamisole Hydrochloride, Levamisole Base, Levamisole API, Raw Material Powder from China in China for almost 10 years.


-Description of Levamisole Base:
 In immunosuppressed states, Levamisole may restore immune function by:
 1) stimulating antibody formation,
 2) stimulating T-cell activation and proliferation,
 3) potentiating monocyte and macrophage phagocytosis and chemotaxis
 4) increasing neutrophil mobility, adherence, and chemotaxis.

-Other benefits of Levamisole:
 Levamisole Base, Levamisole Hydrochloride API, Raw Material Powder other information.png 

-Description and usage of Levamisole Hydrochloride: 

Levamisole Hydrochloride or Levamisole Hcl  is an anti-helminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and T-lymphocyte function. Paradoxically, this immune enhancement appears to be beneficial in rheumatoid arthritis where dermatitis, leukopenia, and thrombocytopenia,
Levamisole Hcl is the hydrochloride salt of the levamisole.  And levamisole is the synthetic imidazothiazole derivative. It has anthelminthic and immunomodulating properties.

-Side Effects of Levamisole Hcl :
Nausea and vomiting may occur.

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Pharmacology:

Levamisole Hcl and Levamisole Base work as an anti-parasitic, immunomodulator and adjuvant in colorectal cancer. It appears to restore depressed immune function through stimulating antibody formation and enhance T-cell response by stimulating T-cell activation and proliferation.

Anti-parasitic action appears to be tied to its agonistic activity towards nicotinic receptors in nematode muscles resulting in spastic paralysis. The net effect is a paralyzing of the worm, which is then expelled alive.

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Levamisole Hydrochloride (Levamisole HCL) raw material API powder, is an anthelmintic (anti-worm) agent commonly applied in large livestock such as cattle, pigs and sheep. In 1970’s, Levamisole Hydrochloride (Levamisole HCL) raw material API powder was proven to have immunostimulatory properties and investigation into its use in humans began to expand. Currently, it is used in humans for diseases related to imbalances in the regulation of immune responses or deficiencies of the immune system, including autoimmune diseases, chronic and recurrent diseases, chronic infections and cancer. Levamisole Hydrochloride (Levamisole HCL) raw material API powder has beneficial effects on host defense mechanisms and restores depressed immune responses in animals and humans.  Another interesting use of Levamisole Hydrochloride (Levamisole HCL) raw material API powder in humans is as a treatment for common warts.

News of its anthelmintic efficacy and immune system benefits has been known among aquatic hobbyists for a lot of years. However, the problem is that there is not much in the way of definitive information on its use and application in the hobby. Anecdotal accounts of how it has worked for those ‘outside the box’ aquarists who first braved its use with fish, and accounts of personal experience with Levamisole in individual aquariums are helpful, but the ‘your mileage may vary’ factor is immense. Word about its usefulness in treating internal parasites in the ornamental fish trade has spread, but information regarding its use is limited and sometimes conflicting. From the information we known for now, Levamisole Hydrochloride (Levamisole HCL) raw material API powder is safe to use in aquaria and effective against many internal parasites, especially nematodes, when used in appropriate dosages. It does not harm the bio-filter, plants, invertebrates or uninfected fish. As an added benefit, Levamisole Hydrochloride (Levamisole HCL) raw material API powder will help to boost the immune competence of fish, humans, large animals, birds and some reptiles.

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COA of Levamisole Base:

Testing Item

Standard

Result

Characters
Levamisole Base

Almost white crystalline power

A white crystalline power.

Specific optical rotation

-85° ~ -89°

-86.67°

Transmittance

≥ 85%

97.60%

Loss on drying

≤0.5%

0.19%

Sulphated ash

≤0.10%

< 0.10%

Assay
     Levamisole Base

99.0% ~101.0%

99.82%

COA of Levamisole Hydrochloride:

Testing Item

Standard

Result

Characters
Levamisole Hydrochloride

A white or almost white crystalline power.

A white crystalline power.

Identification
Levamisole Hcl

It complies with the test for specific optical rotation.

Complies

IR

Complies

Gives reaction of chlorides

Complies

Appearance  of  solution

Meets the requirements

Complies

pH

3.0 ~ 4.5

4.22

Specific optical rotation

-121° ~ -128°

-121.06°

Related substances

Impurities A, B, C, D, E≤0.2%

A:0.01%,
     B:0.00%
     C:0.08%,
     D:0.00%,  
     E:0.00%

Any other impurity ≤0.10%

0.01%

Total impurities≤0.3%

0.05%

Heavy metals

≤0.002%

< 0.002%

Loss on drying

≤0.5%

0.07%

Sulphated ash

≤0.1%

0.06%

Assay

98.5% ~101.0%
     Levamisole Hydrochloride

100.28%

Conclusion: Our product complies with BP and EP standard.

Top Quality, Pure China Levamisole Hcl, Levamisole Base Powder/Substance factory in China; China Levamisole Hydrochloride, Levamisole Base Raw Material Suppliers in China. China Levamisole Hydrochloride, Levamisole Base API Manufacturers in China. 


If you are looking for the Levamisole Base CAS 14769-73-4 Levamisole Hydrochloride API, Raw Material Powder CAS 16595-80-5, welcome to contact us. We are one of the leading and professional China manufacturers and suppliers in this field. Competitive price and good after-sale service are available.
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