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Hydrocortisone Butyrate Raw Material, API CAS 13609-67-1

Hydrocortisone Butyrate Raw Material, API CAS 13609-67-1

Hydrocortisone Butyrate Raw Material, API CAS 13609-67-1 Product Name: Hydrocortisone Butyrate Synonym s: Hydrocortisone 17-butyrate; Hydrocortison Butyrate CAS Number: 13609-67-1 Characteristics: White to practically white, Practically odorless crystalline powder Assay: 97% ~ 102% Hydrocortisone Butyrate...

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Hydrocortisone Butyrate Raw Material, API CAS 13609-67-1

Hydrocortisone Butyrate Raw Material, API.jpg

Product Name:  Hydrocortisone Butyrate Raw Material, API

Synonyms:  Hydrocortisone 17-butyrate; Hydrocortison Butyrate

CAS Number: 13609-67-1

Characteristics: White to practically white, Practically odorless crystalline powder

Assay: 97% ~ 102% Hydrocortisone Butyrate Raw Material, API

Formula: C25H36O6 

Hydrocortisone Butyrate Raw Material, API formula.jpg

KEYWORD: Hydrocortisone Butyrate

Standard: Hydrocortisone Butyrate USP

Package: 5kg/tin,2tins/carton.

 

Description & Mechanism:  

Hydrocortisone Butyrate Raw Material, API is the butyrate salt form of hydrocortisone. It is a synthetic glucocorticoid receptor agonist. Hydrocortisone Butyrate have anti-inflammatory, anti-pruritic and vasoconstrictive ability. It will Bind and activate the glucocorticoid receptor results in the activation of lipocortin that in turn inhibits cytosolic phospholipase A2. Lack of phospholipase A2 prevents the release of arachidonic acid, precursor for inflammatory mediator prostaglandins and leukotrienes, from the cell membrane.

Secondly, with Hydrocortisone Butyrate help, mitogen-activated protein kinase (MAPK) phosphatase 1 is induced, thereby leading to dephosphorylation and inactivation of Jun N-terminal kinase directly inhibiting c-Jun mediated transcription.

Finally, Hydrocortisone Butyrate’s other good function: transcriptional activity of nuclear factor (NF)-kappa-B is blocked, thereby inhibits the transcription of cyclooxygenase 2.  This is essential for prostaglandin production.

 Hydrocortisone butyrate API, Raw Material is approved for the treatment of many types of skin conditions, including psoriasis, dermatitis, and eczema. Hydrocortisone butyrate belongs to steroids, and it works by reducing inflammation and suppressing an overactive immune system. Hydrocortisone butyrate API, Raw Material can be made into several forms such as Hydrocortisone butyrate cream, ointment, lotion, and liquid.

Hydrocortisone butyrate will form an oily layer on the top of the skin to retain water in the skin.

 

As a professional China Hydrocortisone Butyrate Raw Material supplier and Manufacturer in China, FENGCHEN GROUP CO., LTD has been supplying and exporting Hydrocortisone Butyrate API from China in China for almost 10 years.


Usage:

Hydrocortisone Butyrate is one of the raw material. It is widely used to manufacture Hydrocortisone Butyrate cream formulation.

 

Hydrocortisone Butyrate Side Effects:

Just like any medicine, Hydrocortisone Butyrate may cause Adverse Reactions. However, not everyone who uses Hydrocortisone Butyrate will suffer such problems. Actually, most people tolerate it quite well and do not have any side effects.

If unwanted adverse reactions do occur, in most cases, they will be minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are rare.

Common side effects of hydrocortisone butyrate may be:

Skin irritation, Spider veins, Itching, Dryness, Burning.


COA of Hydrocortisone Butyrate

Product    Name

Hydrocortisone    Butyrate

Testing Item

Standard

Result

Appearance

White    to practically white, Practically odorless crystalline powder

Complies

Clarity of Solution

Should comply.

Complies

Identification
 (Hydrocortisone    Butyrate)

Should comply.

Complies

Specific    Rotation

+47°    ~ +54°

+47.7°

Loss    on drying

≤    1.0%

0.38%

Related    Substances

Total    Impurity ≤ 2.0%
 Individual    Impurity ≤ 1.0%

0.74%
 0.35%

Residual Solvents

Should comply.

Complies

Assay
 (Hydrocortisone    Butyrate)

97.0%    ~ 102.0%

99.44%

Top Quality, China Pure Hydrocortisone Butyrate Powder/Substance factory in China;  China Hydrocortisone Butyrate Raw Material Supplier in China. China Hydrocortisone Butyrate API Manufacturer in China. 

 


If you are looking for the Hydrocortisone Butyrate Raw Material, API CAS 13609-67-1, welcome to contact us. We are one of the leading and professional China manufacturers and suppliers in this field. Competitive price and good after-sale service are available.
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