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Loxoprofen Sodium Hydrate CAS 80382-23-6

Loxoprofen Sodium Hydrate CAS 80382-23-6

China Loxoprofen Sodium Hydrate Suppliers, Manufacturers CAS 80382-23-6 Product Name: Loxoprofen Sodium Hydrate Synonyms: Loxoprofen Sodium, Loxoprofen Sodium Hydrate CAS Number: 80382-23-6 Characteristics: White to yellowish white crystals or crystalline powder Assay: ≥ 98.5% Loxoprofen Sodium...

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China Loxoprofen Sodium Hydrate Suppliers, Manufacturers CAS 80382-23-6

    Loxoprofen Sodium Hydrate .png


Product Name: Loxoprofen Sodium Hydrate

Synonyms: Loxoprofen Sodium, Loxoprofen Sodium Hydrate

CAS Number: 80382-23-6

Characteristics: White to yellowish white crystals or crystalline powder

Assay:  ≥ 98.5% Loxoprofen Sodium

Formula: C15H17NaO3

Structure Formula: 

Loxoprofen Sodium Hydrate formula.png

Package information:  25Kg/Fiber DrumCardboard DrumPaper Drum

KEY Words: Loxoprofen Sodium Raw Material, API

Chemical Name: Synonyms: Sodium 2-[4-(2-Oxocyclopentyl-1-methyl)phenyl]propionate dehydrate

Standard: JP16

Description and Usage:
Loxoprofen Sodium Hydrate is a non-selective non-steroidal anti-inflammatory drug. It has been effective in reducing atherosclerosis in mice by reducing inflammation. Loxoprofen Sodium becomes active after metabolism in the body and inhibits the activation of cyclooxygenase.
 In addition to anti-inflammatory actions, Loxoprofen Sodium Hydrate has analgesic, antipyretic, and platelet-inhibitory actions. 
 As most NSAIDs, Loxoprofen sodium is a non-selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid.

Loxoprofen sodium is a non-steroidal anti-inflammatory drug, or NSAID, marketed under various trade names in Brazil, Japan, Argentina and Mexico. Loxoprofen is in the same chemical family as ibuprofen, naproxen and ketoprofen. Loxoprofen sodium, ibuprofen, naproxen and ketoprofen all work by inhibiting enzymes which will help to produce inflammatory chemicals in our bloodstream. Less inflammation will let us feel less pain, so NSAID’s most important usage is for the patients who suffer from acute and chronic pain.

 

As a professional China Loxoprofen Sodium and Loxoprofen Raw Material, API supplier and Manufacturer in China, FENGCHEN GROUP CO., LTD has been supplying and exporting Loxoprofen Sodium and Loxoprofen Raw Material, API from China in China for almost 10 years.

 

Enzyme Blockade:

Loxoprofen Sodium and Loxoprofen Raw Material, API will interfere with the activity of two crucial cyclooxygenase enzymes, named COX-1 and COX-2. They are 2 enzymes which are responsible for producing prostaglandins. Prostaglandins participate in many biological processes, such as activation of the inflammatory response, modulation of immune function, generation of fever, blood clotting, digestion, blood vessel dilation and constriction, fertility, labor, etc. With no or less prostaglandins, Loxoprofen Sodium and Loxoprofen Raw Material, API will finally affect the normal physiologic functions. Thereforoe, the property that accounts for Loxoprofen Sodium and Loxoprofen’s benefits is also responsible for the possible side effects.

 

Broad Effects:

Loxoprofen is a nonselective NSAID that inhibits both COX-1 and COX-2, so its spectrum of side effects. Just like other non-selective NSAIDs, spectrum of Loxoprofen Sodium and Loxoprofen Raw Material, API are relatively broad. Loxoprofen is available in both oral and topical forms. Topical usage of Loxoprofen Sodium and Loxoprofen Raw Material, API may lead to localized irritation, which is called contact dermatitis. Luckily, it is very rarely to cause systemic side effects, such as diarrhea, constipation, abdominal pain, heartburn, headaches, ringing in your ears or prolonged bleeding following minor injuries. Although very rare and seldom reported, some more serious side effects may also occur.


COA of Loxoprofen Sodium :


     Testing Item

Standard

Result

Appearance
Loxoprofen Sodium

White to yellowish white crystals or crystalline powder

Complies

Solubility

Very soluble in water and in methanol, freely soluble in ethanol(95), practically insoluble in diethyl ether

Complies

Optical Rotation

Not show optical rotation

Complies

Identification
Loxoprofen Sodium

UV Absorption: Compare the spectrums between the solution of Loxoprofen sodium and CRS, both spectra exhibits similar intensities of absorption at the same wavelengths

Complies

IR Absorption: Compare the infrared absorption spectrum of Loxoprofen sodium with the reference Spectrum: Both spectra exhibit similar intensities of absorption at the same wave numbers

Complies

Sodium test: Positive

Complies

pH

6.5 ~ 8.5

8.1

Clarity & Color of solution

Solution is clear and colorless or pale yellow. The color is not darker than that of diluted Matching Fluid for Color A

Clear, colorless

Heavy Metal

≤ 10ppm

< 10ppm

Related Substances

The spots other than the principal spot from the sample solution are not more intense than the spot from the standard solution.

Complies

Water

11.0% ~ 13.0%

12.0%

Assay
Loxoprofen Sodium

≥ 98.5%

99.8%

Other Names:

Loxoprofen sodium dihydrate

Sodium 2-(4-(2-oxocyclopentylmethyl)phenyl)propionate dihydrate

alpha-Methyl-4-((2-oxocyclopentyl)methyl)benzeneacetate sodium salt dihydrate

Benzeneacetic acid, alpha-methyl-4-((2-oxocyclopentyl)methyl)-, sodium salt, dihydrate

sodium 2-{4-[(2-oxocyclopentyl)methyl]phenyl}propanoate hydrate (1:1:2)

sodium 2-{4-[(2-oxocyclopentyl)methyl]phenyl}propanoate

 

Top Quality, China Pure Loxoprofen Sodium Powder/Substance factory in China; China Loxoprofen Sodium Raw Material Suppliers in China. China Loxoprofen Sodium API Manufacturers in China. 


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Loxoprofen Sodium Hydrate CAS 80382-23-6


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