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Candesartan Cilexetil Raw Material, API BP, EP, USP CAS 145040-37-5

Candesartan Cilexetil Raw Material, API BP, EP, USP CAS 145040-37-5

China Candesartan Cilexetil Suppliers, Candesartan Cilexetil Manufacturers CAS 145040-37-5 Product Name: Candesartan Cilexetil Raw Material, API BP, EP, USP CAS 145040-37-5 Synonyms: Candesartan hexetil CAS Number: 145040-37-5 Characteristics: White to off white powder Assay: 98.7% ~ 101.0% Formula: C33H34N6O6 Candesartan Cilexetil...

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China Candesartan Cilexetil Suppliers, Candesartan Cilexetil Manufacturers CAS 145040-37-5

Candesartan Cilexetil Raw Material, API BP, EP, USP.jpg

Product Name: Candesartan Cilexetil Raw Material, API 

Synonyms: Candesartan hexetil

CAS Number: 145040-37-5

Characteristics: White to off white powder

Assay:  98.7% ~ 101.0%

Formula: C33H34N6O6 Candesartan Cilexetil

Structure Formula:

Candesartan Cilexetil Raw Material, API BP, EP, USP formula.jpg

Package information: 25Kgs/Drum

KEY Words: Candesartan Cilexetil Raw Material, API BP, EP, USP CAS 145040-37-5

Standard: USP38 Standard Candesartan Cilexetil

 

Description & Function & Usage of Candesartan Cilexetil:

(1) Candesartan Cilexetil used as Angiotensin II Type 1 Receptor Blockers

(2) Candesartan Cilexetil can be Antihypertensive

Candesartan Cilexetil is used to treat some acute or chronic vascular hypertension regardless of pharmacological mechanism.

Candesartan cilexetil Raw Material, API is a drug used for treating high blood pressure (hypertension). It is in a class of drugs called angiotensin receptor blockers (ARBs) which includes losartan, valsartan, and irbesartan. Angiotensin, formed in the blood by the action of angiotensin converting enzyme (ACE), is a powerful chemical that attaches to angiotensin receptors found in many tissues but primarily on smooth muscle cells surrounding blood vessels. Angiotensin's attachment to the receptors causes the muscle cells to contract and the blood vessels to narrow which will end up in increased blood pressure. Candesartan cilexetil raw material, API blocks the angiotensin receptor. Therefore this process will help to prevent the action of angiotensin. As a result, blood vessels will expand and blood pressure will be lower. A lower high blood pressure will minimize the risk of strokes, heart attacks, and kidney problems. Candesartan cilexetil raw material, API works by relaxing blood vessels so blood can flow more easily.

Candesartan cilexetil raw material, API belongs to a class of drugs called angiotensin receptor blockers.

 

As a nonpeptide, Candesartan cilexetil, is chemically described as (±)-1-Hydroxyethyl 2-ethoxy-1-[p-(o-1H-tetrazol-5-ylphenyl)benzyl]-7-benzimidazolecarboxylate, cyclohexyl carbonate (ester).

Following oral administration, candesartan cilexetil undergoes hydrolysis at the ester link to form the active drug, candesartan, which is achiral.

 

Fengchen Group is a leading supplier of Candesartan Cilexetil Raw Material, API BP, EP, USP from China in China. We specialize in wholesale and bulk amounts, ensuring all our clients have the right supplier of Candesartan Cilexetil Raw Material, API BP, EP, USP when they need it. When you are going to buy or purchase Candesartan Cilexetil Raw Material, API BP, EP, USP, please turn to Fengchen Group.

As a professional China Candesartan Cilexetil Raw Material, API BP, EP, USP supplier and Manufacturer in China, FENGCHEN GROUP CO., LTD has been supplying and exporting Candesartan Cilexetil Raw Material, API BP, EP, USP from China in China for almost 10 years.

 

Properties:

Appearance: Candesartan cilexetil is a white to off-white powder.

Molecular weight of 610.67.

Candesartan cilexetil Solubility: Practically insoluble in water and sparingly soluble in methanol. Candesartan cilexetil is a racemic mixture containing one chiral center at the cyclohexyloxycarbonyloxy ethyl ester group.

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Side Effects

Most people using this medication do not have serious side effects.

However, few people may suffer fainting, decreased sexual ability, etc.

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COA of Candesartan Cilexetil

Name of Product

Candesartan Cilexetil

Testing Item

Standard

Result

Appearance  

White to off white powder

White powder

Solubility

Practically insoluble in water, sparingly soluble in methanol

Conforms

Identification A

(Candesartan Cilexetil)

IR: Should be identical to that of Candesartan Cilexetil

Complies

Identification B

(Candesartan Cilexetil)

Retention time of the major peak of the sample solution corresponds to that of Candesartan Cilexetil

Complies

Water

≤ 0.3%

0.08%

Residual on Ignition

≤ 0.1%

0.02%

Related Compounds

Ethyl Candesartan ≤ 0.2%

0.02%

Desethyl Candesartan Cilexetil ≤ 0.3%

0.02%


N2-Ethyl Candesartan Cilexetil ≤ 0.2%

0.02%


Any other unknown impurity ≤ 0.1%

0.01%


Total impurities ≤ 0.60%

0.11%


Acetone

≤ 5000ppm

65ppm

Methanol

≤ 3000ppm

<LOD (LOD=12ppm)

Ethanol

≤ 5000ppm

<LOD (LOD=18ppm)

Methylene Chloride

≤ 600ppm

<LOD (LOD=7ppm)

Diethyl Ether

≤ 5000ppm

<LOD (LOD=2ppm)

Ethyl Acetate

≤ 5000ppm

<LOD (LOD=5ppm)

Dimethylformamide

≤ 880ppm

<LOD (LOD=13ppm)

Assay (Candesartan Cilexetil)

98.7% ~ 101.0%

100.0%


Top Quality, China Pure Candesartan Cilexetil Powder/Substance factory in China; China Candesartan Cilexetil Raw Material Suppliers in China. China Candesartan Cilexetil API Manufacturers in China. 


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Candesartan Cilexetil Raw Material, API BP, EP, USP CAS 145040-37-5


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Skype: frankrenful2002
E-Mail: frank_feng@fengchengroup.com
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Add: Room 1101, 5th Building, No.168 Shenzhen Road, Qingdao, China
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