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Amiodarone Hcl or Amiodarone Hydrochloride Powder Raw Material, API CAS 19774-82-4

Amiodarone Hcl or Amiodarone Hydrochloride Powder Raw Material, API CAS 19774-82-4

Amiodarone Hcl or Amiodarone Hydrochloride Powder Raw Material, API CAS 19774-82-4 Product Name: Amiodarone Hcl or Amiodarone Hydrochloride Synonyms: (2-Butyl-3-Benzofuranyl)[4-[2-(Diethylamino)Ethoxy]-3,5-Diiodophenyl]Methanone CAS Number: 19774-82-4 Characteristics: White or almost white, fine, crystalline powder...

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Product Details

Amiodarone Hcl or Amiodarone Hydrochloride CAS 19774-82-4

Amiodarone Hcl or Amiodarone Hydrochloride Powder Raw Material, API.png


Product Name: Amiodarone Hcl or Amiodarone Hydrochloride

Synonyms: (2-Butyl-3-Benzofuranyl)[4-[2-(Diethylamino)Ethoxy]-3,5-Diiodophenyl]Methanone

CAS Number: 19774-82-4

Characteristics: White or almost white, fine, crystalline powder

Assay:  99.0% Min Amiodarone Hcl or Amiodarone Hydrochloride

Formula:  C25H29I2NO3.HCl 

Structure Formula: 

Amiodarone Hcl or Amiodarone Hydrochloride Powder Raw Material, API formula.png

Package information: 25Kg/Fiber DrumCardboard DrumPaper Drum

KEY Words: Amiodarone Hcl, Amiodarone Hydrochloride Powder Raw Material, API

Description:
Amiodarone Hcl is also called Amiodarone Hydrochloride.
Amiodarone Hcl or Amiodarone Hydrochloride  is A non-selective ion channel blocker. Antiarrhythmic (class III).
It inhibits binding of 1,4-dihydropyridine to L-type Ca2+ channels, a/b-adrenergic receptor antagonist, and coronary vasodilator.

Chemical Name of Amiodarone Hcl or Amiodarone Hydrochloride:(2-Butylbenzofuran-3-yl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone hydrochloride.

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If we are doing to take Amiodarone Hcl or Amiodarone Hydrochloride, we should be very carful if there is the following symptom:

Hepatic disease, cirrhosis; Hashimoto's thyroiditis, goiter, thyrotoxicosis, or history of other thyroid dysfunction; CHF, left ventricular dysfunction; hypersensitivity to iodine; older adults; Fabry disease, especially with visual disturbances; electrolyte imbalance, hypokalemia, hypomagnesemia, hypovolemia; preexisting lung disease.

 

Amiodarone Hcl or Amiodarone Hydrochloride Adverse Effects:

CNS: Peripheral neuropathy (muscle weakness, wasting numbness, tingling), fatigue, abnormal gait, dyskinesias, dizziness, paresthesia, headache. CV: Bradycardia, hypotension (IV), sinus arrest, cardiogenic shock, CHF, arrhythmias; AV block. Special Senses: Corneal microdeposits, blurred vision, optic neuritis, optic neuropathy, permanent blindness, corneal degeneration, macular degeneration, photosensitivity. GI: Anorexia, nausea, vomiting, constipation, hepatotoxicity. Metabolic: Hyperthyroidism or hypothyroidism; may cause neonatal hypo- or hyperthyroidism if taken during pregnancy. Respiratory: (Pulmonary toxicity) Alveolitis, pneumonitis (fever, dry cough, dyspnea), interstitial pulmonary fibrosis, fatal gasping syndrome with IV in children. Skin: Slate-blue pigmentation, photosensitivity, rash. Other: With chronic use, angioedema.

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As a professional China Amiodarone Hcl or Amiodarone Hydrochloride Raw Material supplier and Manufacturer in China, FENGCHEN GROUP CO., LTD has been supplying and exporting Amiodarone Hcl or Amiodarone Hydrochloride from China in China for almost 10 years.


Main indexes of Amiodarone Hcl or Amiodarone Hydrochloride:


     Testing Item

Standard

Result

Appearance
Amiodarone Hcl

White or almost white, fine, crystalline powder

Complies

Water Solubility

Very slightly soluble

Complies

Methanol Solubility

Soluble

Complies

Methylene Chloride Solubility

Freely Soluble

Complies

Ethanol Solubility

Sparingly Soluble

Complies

PH

3.2~3.8

4.7

Identification: Amiodarone Hcl
(1)Infrared Absorption
(2)Chloride


Positive (Amiodarone Hydrochloride)
       Positive (Amiodarone Hydrochloride)


Complies
       Complies

Appearance of solution

Clear and NMT GY5 or BY3

Complies

Iodides

≤  0.015%

<0.015%

Heavy Metals

≤  20ppm

<20ppm

Loss on drying

≤  0.5%

0.08%

Sulphated Ash

≤  0.1%

0.06%

Related substance

Total impurity≤  0.5%
     Any impurity≤ 0.2%
     Impurity H (TLC) ≤ 0.02%

Complies
     Complies
     Complies

Assay 
Amiodarone Hydrochloride

98.5%~101.0%

99.76%

Our Amiodarone Hcl complies with BP and EP standard.

Top Quality, China Pure Amiodarone Hcl or Amiodarone Hydrochloride Powder/Substance factory in China;  China Amiodarone Hcl or Amiodarone Hydrochloride Raw Material Suppliers in China. China Amiodarone Hcl or Amiodarone Hydrochloride API Manufacturers in China. 


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Skype: frankrenful2002
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Add: Room 1101, 5th Building, No.168 Shenzhen Road, Qingdao, China
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