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Spectinomycin Hcl or Spectinomycin Hydrochloride Raw Material, API powder CAS 22189-32-8

Spectinomycin Hcl or Spectinomycin Hydrochloride Raw Material, API powder CAS 22189-32-8

Spectinomycin Hcl or Spectinomycin Hydrochloride Raw Material, API powder CAS 22189-32-8 CAS 22189-32-8 Product Name: Spectinomycin Hcl or Spectinomycin Hydrochloride Synonyms: Spectinomycin Dihydrochloride Pentahydrate, spectinomycin hydrochloride hydrate CAS Number: 22189-32-8 Characteristics: White or almost white powder, slightly...

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Product Details

Spectinomycin Hcl or Spectinomycin Hydrochloride CAS 22189-32-8

Spectinomycin Hcl or Spectinomycin Hydrochloride Raw Material, API powder.png


Product Name: Spectinomycin Hcl or Spectinomycin Hydrochloride

Synonyms: Spectinomycin Dihydrochloride Pentahydrate, spectinomycin hydrochloride hydrate

CAS Number: 22189-32-8

Characteristics: White or almost white powder, slightly hygroscopic.

Assay: please see the indexes as following COA

Formula:  C14H36Cl2N2O12

Structure Formula: 

Spectinomycin Hcl or Spectinomycin Hydrochloride Raw Material, API powder formula.png

Standard: BP, USP, EP
Package information: 10BOU/Drum
KEY Words: Spectinomycin Hcl, Spectinomycin Hydrochloride, Spectinomycin Dihydrochloride Pentahydrate API Raw Material Powder

Description:
Spectinomycin Hcl is also called Spectinomycin Hydrochloride. The more exact name is Spectinomycin Dihydrochloride Pentahydrate. It is an antibiotic working against gram-negative and Gram-positive bacteria. For example,  Spectinomycin Hcl can be used to treat gonorrhea.
It is antibiotic derived from Streptomyces spectabilis with bacteriostatic activity. Spectinomycin Hcl or Spectinomycin Hydrochloride binds to the bacterial 30S ribosomal subunit. By this way, it interferes with the initiation of protein synthesis and with proper protein elongation. Spectinomycin Hcl interrupts protein synthesis by interfering with peptidyl tRNA translocation.
This is the mechanism of Spectinomycin Hcl, how it kills bacterial cell.

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Overview:

Spectinomycin Hcl, Spectinomycin Hydrochloride, Spectinomycin Dihydrochloride Pentahydrate Raw Material, API powder is an aminocyclitol antibiotic derived from Streptomyces spectabilis. Spectinomycin Hcl, Spectinomycin Hydrochloride Raw Material, API powder is structurally related to aminoglycosides. Spectinomycin lacks amino sugar and glycosidic bonds. Spectinomycin has moderate antibacterial properties against many gram positive and gram negative bacteria but Spectinomycin Hcl, Spectinomycin Hydrochloride, Spectinomycin Dihydrochloride Pentahydrate Raw Material, API powder is especially effective against Niesseria gonorrhoeae. Antibiotics require constant drug level In body for therapeutic effect. It is achieved by taking the medication at regular intervals of time throughout the day and night as prescribed. It is important to take Spectinomycin Hcl, Spectinomycin Hydrochloride, Spectinomycin Dihydrochloride Pentahydrate Raw Material, API powder containing drugs. Discontinuation of this drug may result in ineffective treatment.

 

As a professional China Spectinomycin Hcl, Spectinomycin Hydrochloride, Spectinomycin Dihydrochloride Pentahydrate Raw Material, API powder supplier and Manufacturer in China, FENGCHEN GROUP CO., LTD has been supplying and exporting Spectinomycin Hcl, Spectinomycin Hydrochloride, Spectinomycin Dihydrochloride Pentahydrate Raw Material, API powder from China in China for almost 10 years.

 

Primary Characteristics:

Molecular Structure of Spectinomycin (HCl)

It is of Semi Synthetic origin and belongs to Aminocyclitol Antibiotic. Spectinomycin Hcl, Spectinomycin Hydrochloride, Spectinomycin Dihydrochloride Pentahydrate Raw Material, API powder belongs to Antibacterial (Proetin synthesis inhibitor) pharmacological group on the basis of mechanism of action and also classified in Antibiotics pharmacological group. The Molecular Weight of Spectinomycin (HCl) is 495.40.

It is weakly acidic drug, 5.66% solution of the drug is isotonic and Its pKa is 6.88, 8.84.

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Spectinomycin Hcl, Spectinomycin Hydrochloride, Spectinomycin Dihydrochloride Pentahydrate Raw Material, API powder is an aminocyclitol antibiotic produced by a species of soil microorganism designated as Streptomyces spectabilis. Sterile spectinomycin hydrochloride is the pentahydrated dihydrochloride salt of spectinomycin.

 

Indications:

Spectinomycin Hcl, Spectinomycin Hydrochloride, Spectinomycin Dihydrochloride Pentahydrate Raw Material, API powder is indicated in the treatment of acute gonorrheal urethritis and proctitis in the male and acute gonorrheal cervicitis and proctitis in the female when due to susceptible strains of Neisseria gonorrhoeae. Men and women with known recent exposure to gonorrhea should be treated as those known to have gonorrhea.

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Spectinomycin Hcl, Spectinomycin Hydrochloride, Spectinomycin Dihydrochloride Pentahydrate Raw Material, API powder is primarily indicated in conditions like Cervicitits, Gonorrhoea, Proctitis, Urethritis.

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Spectinomycin Hcl, Spectinomycin Hydrochloride, Spectinomycin Dihydrochloride Pentahydrate Raw Material, API powder is a chemical substance derivable from a mold or bacterium that can kill microorganisms and cure bacterial infections; "when antibiotics were first discovered they were called wonder drugs"

 

Spectinomycin Hcl, Spectinomycin Hydrochloride, Spectinomycin Dihydrochloride Pentahydrate Raw Material, API powder is a broad-spectrum antibiotic, C14H24N2O7, obtained from a species of gram-negative bacteria (Streptomyces spectabilis) or produced synthetically and used in its hydrochloride form especially in the treatment of penicillin-resistant gonorrhea.

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Side Effects:

Spectinomycin Hcl, Spectinomycin Hydrochloride, Spectinomycin Dihydrochloride Pentahydrate Raw Material, API powder produces potentially life-threatening effects which include Anaphylaxis. which are responsible for the discontinuation of Spectinomycin (HCl) therapy.

 The symptomatic adverse reactions produced by Spectinomycin (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Nausea, Fever, Chills, Urticaria.

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Main indexes of Spectinomycin Hcl, Spectinomycin Hydrochloride

Testing Item

Standard

Result

Appearance
Spectinomycin Hcl

White or almost white powder, slightly hygroscopic. Freely soluble in water, very slightly soluble in ethanol (96%)

Complies

Identification A
Spectinomycin Hydrochloride

Infrared absorption spectrophotometry.

Complies

Identification B
Spectinomycin Hydrochloride

Gives reaction of Chlorides

Complies

PH

3.8~5.6

5.2

Specific Optical Rotation

+15º~ +21º

+17.0 º

Moisture

16.0%~20.0%

18.1%

Sulphated Ash

&≤1.0%

0.4%

Related substance

&≤1.0%

<1.0%

Assay
(Anhydrous Substance GC)

95.0%~100.5%
     Spectinomycin Hcl

95.7%

Assay
(Hydrous Substance GC)
Spectinomycin Hcl

-------

78.355%

Potency (Hydrous Substance GC) 

Spectinomycin Hydrochloride

-------

642IU/mg

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