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Rifampicin or Rifampin CAS 13292-46-1

Rifampicin or Rifampin CAS 13292-46-1

Rifampicin or Rifampin CAS 13292-46-1 Product Name: Rifampicin Types: Rifampicin 0.5; Rifampicin 0.7 Density: 0.3g/ml; 0.5g/ml; 0.7g/ml; 0.8g/ml Synonyms: Rifampin, Rifampicinum Chemical Name: 3-{[(4-Methyl-1-piperazinyl)imino]-methyl}rifamycin CAS Number: 13292-46-1 Characteristics: A...

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Rifampicin or Rifampin CAS 13292-46-1                                              Rifampicin or Rifampin raw material API BP EP USP.jpg

Product Name:  Rifampicin

Types:  Rifampicin 0.5;  Rifampicin 0.7

Density: 0.3g/ml; 0.5g/ml; 0.7g/ml; 0.8g/ml

Synonyms:  Rifampin, Rifampicinum

Chemical Name: 3-{[(4-Methyl-1-piperazinyl)imino]-methyl}rifamycin

CAS Number: 13292-46-1

Characteristics: A reddish-brown or brownish-red crystalline powder.

Solubility:  slightly soluble in acetone, in alcohol and in ether; soluble in methanol; slightly soluble in water.

Assay:  97.0%~102.0% Rifampicin

Standard: Rifampicin 0.5;  Rifampicin 0.7 BP, EP, USP

Formula: C43H58N4O12

Rifampicin or Rifampin raw material API BP USP EP Formula.gif

Package: 20Kgs or 25Kgs/Paper Drum

Storage: a temperature not exceeding 25C, carefully sealed container , protected from direct sunshine.

Shelf Life: 3 Years (36 Months)

 

Description:

Rifampicin, also known as Rifampin, is a semi-synthetic anti-biotic. It is produced from Streptomyces mediterranei. Rifampicin has a broad anti-bacterial spectrum, with the property against several types of Mycobacterium. For the specific susceptible organisms, Rifampicin or Rifampin inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. By this way, Rifampicin suppresses the initiation of RNA synthesis. Rifampicin itself is bactericidal, and it acts on both intracellular and extracellular organisms.

 Rifampicin is an antibiotic that inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, Rifampicin interacts with bacterial RNA polymerase. But Rifampicin or Refampin doesn’t inhibit the mammalian enzyme. Rifampicin will fight against most gram-positive and gram-negative organisms. Because of Rifampicin’s quick emergence of resistant bacteria, Refampin is restricted to treat mycobacterial infections and a few other indications. Rifampicin will be well absorbed after orally taken and it is distributed widely in body tissues and fluids. Normally, Rifampicin will be metabolized in our liver and will be eliminated in bile and, to some extent, in urine.  Dose adjustments of Rifampicin are unnecessary with renal insufficiency. It will be Well absorbed from gastrointestinal tract.

 

Mechanism of Action:

Rifampicin or Rifampin acts by the inhibition of DNA-dependent RNA polymerase, resulting a suppression of RNA synthesis or the bacteria cell death.

 

As a professional China Rifampicin or Rifampin Raw Material supplier and Manufacturer, FENGCHEN GROUP CO., LTD has been supplying and exporting Rifampicin or Rifampin API from China for almost 10 years.


Rifampicin Usage:

Rifampicin (Rifampin) is the Anti-biotic not only can treat but also prevent tuberculosis and some other related infections.  It is only workable for bacteria. Not effective to viral caused tuberculosis and viral infections.  For example, the common fever or flu.  Rifampicin is very likely to be used with other APIs. For the preparations: “Rifampicin Capsules”, “Rafampicin Tablets”, “Rafampicin Oral Suspensions” and “Rafampicin Paste”. Please use it strictly under professional instructions. 

Certificate of Analysis: Rifampicin (Rifampin)

Testing   Item

Standard

Appearance

A brownish-red crystalline powder.

Identification

Rifampicin   (Rifampin)

Should comply

PH

4.0~6.5

Rifampin Quinone

≤1.5%

One peak

≤1.0%

Sume of Peaks

≤3.5%

Heavy Metal

≤20ppm

Loss on drying

≤1.0%

Sulphated ash

≤0.1%

Assay

--Rifampicin   (Rifampin)

97.0%~102.0%

 

Top Quality, Pure Rifampicin (Rifampin) Powder;  Rifampicin (Rifampin) Raw Material Supplier in China. Rifampicin (Rifampin) API Manufacturer. 


If you are looking for the rifampicin or rifampin cas 13292-46-1, welcome to contact us. We are one of the leading and professional China manufacturers and suppliers in this field. Competitive price and good after-sale service are available.

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