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Oxytetracycline Dihydrate Base CAS 6153-64-6 and Oxytetracycline Hydrochloride or Oxytetracycline HCL CAS 2058-46-0

Oxytetracycline Dihydrate Base CAS 6153-64-6 and Oxytetracycline Hydrochloride or Oxytetracycline HCL CAS 2058-46-0

Oxytetracycline Dihydrate Base CAS 6153-64-6 and Oxytetracycline Hydrochloride or Oxytetracycline Hcl CAS 2058-46-0 Usage: Oxytetracycline Dihydrate Base and Oxytetracycline Hydrochloride (Oxytetracycline Hcl) are the raw material powder to make preparations both for human and animals. For...

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Oxytetracycline Dihydrate Base CAS 6153-64-6 and Oxytetracycline Hydrochloride or Oxytetracycline Hcl CAS 2058-46-0                                              Oxytetracycline Dihydrate Base and Oxytetracycline Hydrochloride or Oxytetracycline HCL.jpg

Product   Name:

Oxytetracycline Dihydrate Base

Oxytetracycline Hydrochloride

Synonyms:

Oxytetracycline,

Oxytetracycline Base,

Oxytetracyclinum   Dihydricum

Oxytetracycline Hcl,

Oxytetracyclini   Hydrochloridum

Characteristics:

Yellow crystalline   powder

Yellow   crystalline powder

CAS   Number:

6153-64-6 or 79-57-2

2058-46-0

Assay:

95.0%~102.0%

95.0%~102.0%

Formula:

C22H24N2O9    2H2O

C22H25ClN2O9    C22H24N2O9 HCl 

Structure:  

Oxytetracycline Dihydrate Base formula.gif

Oxytetracycline Hydrochloride or Oxytetracycline HCL formula.jpg

Package:

25Kg/Fiber DrumCardboard DrumPaper Drum

25Kg/   Drum

Oxytetracycline Base and Oxytetracycline Hydrochloride description:

Oxytetracycline Base and Oxytetracycline hcl are both known as a broad-spectrum anti-biotic. They both have good activity against a wide range of infections. Oxytetracycline is the second of the tetracyclines to be discovered. Oxytetracycline Hcl, just like other tetracyclines, is used to treat and cure some common infections. Its better absorption profile makes Oxytetracycline Hydrochloride preferable to tetracycline for moderately severe acne, but alternatives should be thought if there is no improvement in 3 months.

Oxytetracycline works by interfering with bacteria’s protein production ability, which is crucial to the bacteria. If there is no such proteins, bacteria is unable to grow or. Oxytetracycline hydrochloride therefore will control infection effectively. While the remaining bacteria will get killed by immune system or die slowly. Oxytetracycline Hcl is a broad spectrum antibiotic which is active against most bacteria. However, some strains of bacteria have developed resistance to this Oxytetracycline Hcl. Underthis condition, the effectiveness of Oxytetracycline will be highly reduced.

 Oxytetracycline is still used to treat infections caused by chlamydia (eg the chest infection psittacosis, the eye infection trachoma, and the genital infection urethritis) and infections caused by mycoplasma organisms (eg pneumonia).

 

As a professional China Oxytetracycline Base and Oxytetracycline Hcl Raw Material supplier and Manufacturer, FENGCHEN GROUP CO., LTD has been supplying and exporting Oxytetracycline Base and Oxytetracycline Hydrochloride API from China for almost 10 years.


Indications of Oxytetracycline Base and Oxytetracycline Hcl:

Oxytetracycline is indicated for treatment of infections caused by a variety of Gram positive and Gram negative microorganisms including 

1. Escherichia coli, 2. Pasteurella pestis , 3.Mycoplasma pneumoniae,4. Diplococcus pneumoniae , 5. Haemophilus influenzae, etc .

 

Mechanism of Action:

Oxytetracycline base and Oxytetracycline Hcl will effect cell growth by inhibiting translation. It binds to the 30S ribosomal subunit. Oxytetracycline base and Oxytetracycline Hcl prevent the amino-acyl tRNA from binding to the A site of the ribosome. Although this kind of binding is reversible in nature. Oxytetracycline is lipophilic. This property allow Oxytetracycline Hcl pass through the cell membrane easily or passively diffuses through porin channels in the bacterial membrane.


Usage: Oxytetracycline Dihydrate Base and Oxytetracycline Hydrochloride (Oxytetracycline Hcl) are the raw material powder to make preparations both for human and animals.

For example: Oxytetracycline Injection, Oxytetracycline Tablets, Oxytetracycline and Nystatin Capsules, Oxytetracycline Hydrochloride Capsules, Oxytetracycline Hydrochloride and Polymyxin B Sulfate Topical Powder, Oxytetracycline Hcl and Polymyxin B Sulfate Vaginal Tablets, Oxytetracycline Hcl and Hydrocortisone Acetate Ophthalmic Suspension

Veterinary:  Oxytetracycline Veterinary Oral Powder, etc

 

Certificate of Analysis : Oxytetracycline Dihydrate Base

Testing Item

Standard

Result

Appearance

Yellow crystalline   powder

Complies

Identification   A 

Oxytetracycline Dihydrate Base

TLC   pass

Complies

Identification   B

Color   reaction with sulphuric acid.

Complies

Identification   C

Opalescence   reaction with silver nitrate

Complies

pH

4.5   ~ 7.5

5.2

Absorbance   at 353nm(pH2.0)

290   ~ 310

296

Specific   optical rotation

-203° ~   -216°

-209.3°

Heavy   Metals

≤50ppm

<50ppm

Light   absorbing impurities A

Absorption   at 430 ≤0.25

0.10

Light   absorbing impurities B

Absorption   at 490 ≤0.20

0.13

Related   Substance

Impurity   A:

Impurity   B:

Impurity   C:

Single   unknown impurities

 

≤   0.5%

≤   2.0%

≤   2.0%

≤   0.1%

 

0.31%

0.74%

1.2%

Not   detected

Sulphated   Ash

≤0.5%

0.1%

Moisture   (Water)

6.0%   ~ 9.0%

7.1%

Assay   (Anhydrous substance)

95.0%   ~ 102.0% Oxytetracycline Dihydrate Base

97.4%

Certificate of Analysis: Oxytetracycline Hydrochloride

Testing Item

Standard

Result

Appearance

Yellow crystalline   powder

Complies

Identification   A

Oxytetracycline Hydrochloride

TLC   pass

Complies

Identification   B

Color   reaction with sulphuric acid.

Complies

Identification   C

Reaction   of chlorides

Complies

Solubility

Should   comply

Complies

pH

2.3~2.9

2.45

Absorbance   at 353nm(pH2.0)

270   ~ 290

277.2

Specific   optical rotation

-188°  ~ -200°

-194°

Heavy   Metals

≤50ppm

<25ppm

Light   absorbing impurities A

Absorption   at 430 ≤0.50

0.27

Light   absorbing impurities B

Absorption   at 490 ≤0.20

0.04

Impurity   A

≤0.5%

0.14%

Impurity   B

≤2.0%

0.54%

Impurity   C

≤2.0%

1.27%

Impurity   D, E and F

≤2.0%

0.52%

Any   other detected impurities

≤0.1%

Undetected

Sulphated   Ash

≤0.5%

0.07%

Moisture

≤2.0%

0.75%

Assay(Oxytetracycline Hcl)

95.0%   ~ 102.0% Oxytetracycline Hydrochloride

96.6%

Top Quality, Pure Oxytetracycline Hcl Powder;  Oxytetracycline Hydrochloride Raw Material Supplier in China. Oxytetracycline Hcl API Manufacturer. 


Related similar product you may interested:    

Oxytetracycline Dihydrate Base CAS 6153-64-6 And Oxytetracycline Hydrochloride Or Oxytetracycline HCL CAS 2058-46-0

Oxytetracycline Dihydrate Base CAS 6153-64-6

Oxytetracycline Hydrochloride Or Oxytetracycline HCL CAS 2058-46-0





If you are looking for the oxytetracycline dihydrate base cas 6153-64-6 and oxytetracycline hydrochloride or oxytetracycline hcl cas 2058-46-0, welcome to contact us. We are one of the leading and professional China manufacturers and suppliers in this field. Competitive price and good after-sale service are available.

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Skype: frankrenful2002
E-Mail: frank_feng@fengchengroup.com
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Add: Room 1101, 5th Building, No.168 Shenzhen Road, Qingdao, China
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