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Neomycin Sulfate or Neomycin Sulphate USP BP EP CAS 1405-10-3

Neomycin Sulfate or Neomycin Sulphate USP BP EP CAS 1405-10-3

Neomycin Sulfate or Neomycin Sulphate USP BP EP CAS 1405-10-3 Product Name: Neomycin Sulfate Synonyms: Neomycin Sulphate, Neomycini sulfas, Fradiomycin Sulfate, Fradiomycin Sulphate CAS Number: 1405-10-3 Characteristics: White to yellowish white hygroscopic powder. Assay: Potency >=680 IU/mg...

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Neomycin Sulfate or Neomycin Sulphate USP BP EP CAS 1405-10-3                                              Neomycin Sulfate or Neomycin Sulphate USP BP EP.jpg

Product Name:  Neomycin Sulfate

Synonyms:  Neomycin Sulphate, Neomycini sulfas, Fradiomycin Sulfate, Fradiomycin Sulphate

CAS Number: 1405-10-3

Characteristics: White to yellowish white hygroscopic powder.

Assay:  Potency >=680 IU/mg

Formula: C23H46N6O13 xH2SO4

Neomycin Sulfate or Neomycin Sulphate USP BP EP formula.gif

 

Neomycin Sulfate Description:

Neomycin Sulfate isused for treating chicken intestinal toxicity syndrome, necrotic enteritis, ulcerative colitis, especially chicken depression caused by intestinal toxin syndrome. 

Neomycin Sulphate is an antibiotic which will kill the bacteria in the body. Neomycin Sulphate reduces the risks of infection during intestines surgery. Symptoms of hepatic coma will also be effectively controlled by Neomycin Sulfate.

Neomycin Sulfate is obtained from the metabolic related products of the actinomycete Streptomyces fradiae. 

Neomycin Sulfate is only absorbed in a very small amount from the normal gastrointestinal tract. The small absorbed fraction is rapidly distributed in the tissues and is excreted by the kidney in keeping with the degree of kidney function. There can be a 97 percents of unabsorbed portion of the Neomycin Sulfate will be eliminated unchanged in the feces.

After the oral administration of Neomycin Sulfate, intestinal bacteria growth will be effectively controlled. The suppression time can be 2 to 3 days.

 

Indications of Neomycin Sulfate:

1.Intestinal Bacteria Suppression: Neomycin Sulfate are indicated as adjunctive therapy as party of a regimen for the suppression of the normal bacterial flora of the bowel. For example, preoperative preparation of the bowel. Neomycin Sulfate is often given concomitantly together with erythromycin containing medicines.  

2.Hepatic Coma: Neomycin Sulfate is known to be helpful for hepatic coma.

The mechanism of action is that Neomycin Sulfate can reduce -forming bacteria which will cause ammonia in intestinal tract, resulting in neurologic improvement.

 

Side effects of Neomycin Sulfate:

The most commonly seen adverse reactions of Neomycin Sulfate are 1.nausea, 2.vomiting and 3.diarrhea. 

 

Neomycin Sulfate Overdose:

Because of its low and poor absorption, Neomycin Sulfate is unlikely to have overdose reaction.  However, a long time Neomycin Sulfate administration may cause sufficient systemic drug levels, which may end with neurotoxicity, ototoxicity. Pharmaceutically speaking, Hemodialysis can eliminate Neomycin Sulfate from blood.

 

As a professional China Neomycin Sulfate Powder supplier and Manufacturer, FENGCHEN GROUP CO., LTD has been supplying and exporting Neomycin Sulfate Raw Material from China for almost 10 years.

 

Contraindications

Neomycin Sulfate oral preparations are contraindicated if there is a intestinal obstruction. If there is a history of hypersensitivity to Neomycin Sulfate, it is also should be careful before using this drug.


Neomycin Sulfate Usage: 

Neomycin Sulfate (Neomycin Sulphate) is Neomycin’s sulfate slat, with anti-bacterial function. Usually, It has a potency 600µg /mg Min. Neomycin Sulfate (Neomycin Sulphate) belongs to Anti-Biotic. This product is usually used to prevent hepatic problems and fight against infections in intestines.  Neomycin Sulfate (Neomycin Sulphate) will kill the bacteria in our system.

 

There are so many preparations available in the market:

(1) By itself, Neomycin Sulfate Tablets, Neomycin Sulfate Oral Solutions, Neomycin Sulfate Ointment.

There are also Creams, eyedrops, preparation. 

(2) For combination therapy, Neomycin Sulfate (Neomycin Sulphate) is working together with Bactiracic Zinc, Dexamethasone Sodium Phosphate, Fluocinolone Acetonide, Fluorometholone, Hydrocortisone, ISoflupredone Acetate, Tetracaine Hcl, Methylprednisolone, etc to manufacture paste, cream and ointment all over the world.

 

Shelf Life: 4 years if properly preserved.

Transportation Requirements: Normal goods, Suitable for all the transport means.

Package: 20Bou/Drum, about 30Kgs/Drum


COA: Neomycin Sulfate

Testing Item

Standard

Result

Characteristics

A   white or yellowish-white powder. Odorless or almost. Hygroscopic

Complies

 

Identification

(Neomycin   Sulfate)

A;B;C  The positive reaction.

Complies  

Solubility

Very   soluble in water, insoluble in acetone, chloroform,ether.

Complies

 

Specific   Rotation

+53.5°   ~ 59.0°

58.5°

Impurity   A

≤2.0%

0.8%

Impurity   C

3%   ~ 15%

Complies

Any   other impurity

Not   more than the area of the principal peak in the chromatogram with RS(B) (5%)

<5%

Total   other impurities

Not   more than 3 times the area of the principal peak in the chromatogram with   RS(B) (15%)

<15%

Acidity   or alkalinity (PH)

5.0-7.5

6.5

Loss   on drying

≤8.0%

4.5%

Disregard   Limit

Area   of the principal peak obtained in the chromatogram with RS(B) (1%)

Complies

Sulphated   Ash

≤1.0%

0.2%

Assay   (Neomycin Sulfate)

 

≥600μg   /mg (DRY

655μg/mg   DRY

647μg/mg   MOIST

 Top Quality, Pure Neomycin Sulfate Powder;  Neomycin Sulfate Raw Material Supplier in China. Neomycin Sulfate API Manufacturer. 


If you are looking for the neomycin sulfate or neomycin sulphate usp bp ep cas 1405-10-3, welcome to contact us. We are one of the leading and professional China manufacturers and suppliers in this field. Competitive price and good after-sale service are available.

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Skype: frankrenful2002
E-Mail: frank_feng@fengchengroup.com
Tel: +86-186-7846 1007
WECHAT: +86-18678461007
WHATSAPP: +86-18678461007
Add: Room 1101, 5th Building, No.168 Shenzhen Road, Qingdao, China
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