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Doxycycline Hyclate or Doxycycline Hydrochloride or Doxycycline HCL CAS 24390-14-5

Doxycycline Hyclate or Doxycycline Hydrochloride or Doxycycline HCL CAS 24390-14-5

Doxycycline Hyclate or Doxycycline Hydrochloride or Doxycycline Hcl CAS 24390-14-5 Product Name: Doxycycline Hyclate Synonyms: Doxycycline Hydrochloride, Doxycycline Hcl, Doxycyclini hyclas CAS Number: 24390-14-5 Characteristics: Yellow hygroscopic crystalline powder. Assay: 95%~102% Formula:...

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Doxycycline Hyclate or Doxycycline Hydrochloride or Doxycycline Hcl CAS 24390-14-5                                              Doxycycline Hyclate or Doxycycline Hydrochloride or Doxycycline HCL picture.jpg

Product Name:  Doxycycline Hyclate

Synonyms: Doxycycline Hydrochloride, Doxycycline Hcl, Doxycyclini hyclas

CAS Number: 24390-14-5

Characteristics: Yellow hygroscopic crystalline powder.

Assay:  95%~102%

Formula:   C22H24N2O8,HC1,½C2H6O,½H2O    Molecular Weight: 512.9      

Doxycycline Hyclate or Doxycycline Hydrochloride or Doxycycline HCL formula.gif 

Package: 25Kg/Fiber DrumCardboard DrumPaper Drum

Drum Size: Diameter 41Cm, Height 40Cm

According to: EP, BP, USP

Description:

Doxycycline Hyclate or Doxycycline Hydrochloride is synthetic tetracycline derivative with antimicrobial property. Animal study researches proves Doxycycline Hyclate may cause less tooth staining than other tetracyclines. Doxycycline Hyclate is used in some certain areas to treat chloroquine-resistant falciparum malaria.

As a long-acting tetracycline  derived from oxytetracycline, Doxycycline Hyclate or Doxycycline Hcl is used to effect bacterial protein synthesis. It will treat certain bacterial infections. Doxycycline Hyclate may be used in combination with other medicines to treat acne or certain amoeba infections. It may also be used to prevent or slow the progression of anthrax after exposure. Doxycycline hyclate will suppress bacteria growth which will allow the  immune system to destroy and kill the bacteria in time.

Some forms of Doxycycline hyclate are widely applied to prevent malaria, treat anthrax or infections caused by mites, ticks, or lice.

 

As a professional China Doxycycline hyclate Raw Material supplier and Manufacturer, FENGCHEN GROUP CO., LTD has been supplying and exporting Doxycycline hyclate API from China for almost 10 years.

 

Doxycycline hyclate Indications:

Doxycycline Hyclate is popularly applied fight against a lot of bacterial infections, like urinary tract infections, Sexually Transmitted Infections, intestinal infections, Respiratory Tract Infections, eye infections, etc. Doxycycline hyclate is also proved to be useful as an alternative to fight against plague, tetanus, Campylobacter fetus.

 

Doxycycline Hyclate Mechanism of Action:

Just like minocycline, Doxycycline Hyclate is lipophilic and is able to pass through the bacteria lipid bilayer with ease. What’s more, Doxycycline Hyclate reversibly binds to the 30 S ribosomal subunits, and will affect bacterial protein synthesis process. Doxycycline Hyclate prevents the apicoplast of Plasmodium falciparum’s normal function. 

Usage: Doxycycline Hyclate belongs to  tetracycline antibiotic. It is also called Doxycycline Hydrochloride, Doxycycline Hcl. In Latin or some other country: Doxycyclini hyclas

It is the raw material to manufacture Doxycycline Hyclate Capsules, Doxycycline Hyclate Tablets, etc.

Doxycycline Hyclate is also widely used in Veterinary Drugs manufacturing process.


NOTES:

-Doxycycline Hyclate should not to be given to the ones who are allergic to any tetracycline type of antibiotic.

-Children who are not exceed 8year old should take Doxycycline Hyclate, except for cases life-threatening disease. Doxycycline Hyclate may lead to a permanent yellowing or graying of the teeth.

- During pregnancy, using Doxycycline Hyclate is forbidden. Because it could be harmful for the unborn child. In some cases. 


Certificate of Analysis -- Doxycycline Hyclate

Product Name: Doxycycline Hyclate

Testing Item

Standard

Result

Appearance  

Doxycycline Hyclate

Yellow   crystalline powder

Complies

Identification   A Doxycycline Hyclate

Should comply with TLC Result

Complies

Identification   B Doxycycline Hyclate

Color reaction with sulfuric acid

Complies

Identification   C Doxycycline Hyclate

Color reaction with silver nitrate

Complies

pH

2.0   ~ 3.0

2.4

Heavy   Metal

≤50ppm

<50ppm

Solubility

Should   Comply.

Complies

Specific   Optical Rotation

-105~   -120°

-115°

Related   Substance

a)   6-epidoxycycline ≤ 2.0%

1.1%

b)   Metacycline ≤ 2.0%

0.1%


c)   4-epidoxycycline ≤ 0.5%

< 0.1%


d)   4-epi-6-epidoxycycline ≤ 0.5%

< 0.1%


e)   Oxytetracyclie ≤ 0.5%

< 0.1%


f)   2-acety-2-decarbamoyldoxycycline ≤0.5%

Not found


g)   any other impurity ≤0.5%

< 0.1%


h)   not identified impurities≤0.1%

Not found


Specific absorbance

(At 349nm)

300-335

320

Light   absorbing impurities

(At   490nm)

≤   0.07

0.02

Ethanol

4.3%   ~ 6.0% (m/m)

4.9%

Moisture

1.4%   ~ 2.8%

1.9%

Sulphated ash

≤   0.4%

0.05%

Assay (Doxycycline Hyclate)

95.0%   ~ 102.0% (C22H25ClN2O8) based on anhydrous, ethanol-free substance

99.3%

Top Quality, Pure Doxycycline Hyclate Powder;  Doxycycline Hyclate Raw Material Suppliers in China. Doxycycline Hyclate API Manufacturers. 


Related similar product you may interested:    

Doxycycline Hyclate Or Doxycycline Hydrochloride Or Doxycycline HCL CAS 24390-14-5




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Skype: frankrenful2002
E-Mail: frank_feng@fengchengroup.com
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Add: Room 1101, 5th Building, No.168 Shenzhen Road, Qingdao, China
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