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Chloramphenicol CAS 56-75-7 and DL-Chloramphenicol

Chloramphenicol CAS 56-75-7 and DL-Chloramphenicol

Chloramphenicol CAS 56-75-7 and DL-Chloramphenicol Usage: Chloramphenicol and DL- Chloramphenicol are very similar products. They are both broad spectrum synthetic anti-biotics. Chloramphenicol and DL- Chloramphenicol can both be given orally or intravenously in our every day use to treat...

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Chloramphenicol CAS 56-75-7 and DL-Chloramphenicol                                              Chloramphenicol and DL-Chloramphenicol.jpg 

Product   Name:

Chloramphenicol

DL-Chloramphenicol

Synonyms:

Chloromycetin,

Chloramfenicol,  

Chloramphenicolum

DL-Chloromycetin,

DL-Chloramfenicol,

DL-Chloramphenicolum

Characteristics:

White   to grayish white or yellow white needle-like crystalline powder

White   or white with greenish-yellowish crystalline powder

CAS   Number:

56-75-7

----

Assay:

98.5%   ~ 102.0%

98%   Min

Formula:

C11H12Cl2N2O5

The same: C11H12Cl2N2O5

Structure:  

Chloramphenicol BP EP USP formula.gif

DL-Chloramphenicol BP, EP, USP formula.jpg

Specification:  

BP   / EP / USP

In-House,   Enterprise Standard

Package:

25Kg/Fiber DrumCardboard DrumPaper Drum

25Kg/   Drum

Chloramphenicol Description:

Chloramphenicol  is a very popular used antibiotic with a relatively simple structure. It was firstly isolated from cultures of Streptomyces venequelae in 1940’s. But for now, Chloramphenicol is mainly produced synthetically. It was the 1st broad-spectrum anti-biotic discovered and approved by human being. DL-Chloramphenicol acts by suppressing  bacteriostatic protein synthesis.

Chloramphenicol is working on a lot of microorganisms, but there can be serious side-effects. Because of the side effects, Chloramphenicol is usually only reserved for the treatment of serious or life-threatening infections caused by certain bacteria such as typhoid fever. Chloramphenicol keeps bacterial from growing by binding to the bacterial ribosome (blocking peptidyl transferase) or even kill the bacteria. Chloramphenicol also inhibits protein synthesis of bacteria.

  

Function of Chloramphenicol:

1. Because DL-Chloramphenicol destroys the vibrios and decreases the diarrhea, It is widely used for treating cholera.

2.Chloramphenicol is effective against tetracycline-resistant vibrios.

3. Chloramphenicol is very easy to find in the ingredient of every day use eye drops or ointment for the treatment of bacterial conjunctivitis.

 

Chloramphenicol mechanism of action:

Chloramphenicol is lipid-soluble. This property allows Chloramphenicol to diffuse through the bacterial cell membrane.

With the ability of binding to 50s subunit of the bacterial ribosome, Chloramphenicol will stop protein synthesis of bacteria. By this way peptide bond formation will be prevented. Chloramphenicol has both bacteriostatic and bactericidal abilities.

 

Chloramphenicol side effects:

There can be mild diarrhea, nausea, or vomiting.

There can also be serious side effects such as damage to the bone marrow.

 

As a professional China Chloramphenicol powder raw material supplier and Manufacturer, FENGCHEN GROUP CO., LTD has been supplying and exporting Chloramphenicol raw material from China for almost 10 years.

 

Important safety information:

Do not exceed the recommended dose or use Chloramphenicol for longer than prescribed time.

Chloramphenicol is workable only against bacteria. It is not effective for treating viral infections.

Long-term or repeated use of chloramphenicol may cause a second infection. 


Chloramphenicol Usage: 

Chloramphenicol and DL- Chloramphenicol are very similar products. They are both broad spectrum synthetic anti-biotics. Chloramphenicol and DL- Chloramphenicol can both be given orally or intravenously in our every day use to treat bacterial infections. It will be easy to find chloramphenicol preparations in drug stores, like Chloramphenicol Capsules,  Chloramphenicol Tablets, Oral Solution, Cream  and chloramphenicol eye drops.  In combination, there are Chloramphenicol and Hydrocortisone Acetate for Ophthalmic Suspension, Chloramphenicol and Polymyxin B Sulfate Ophthalmic Ointment, Chloramphenicol and Prednisolone Ophthalmic Ointment, etc.

 

Certificate of Analysis-- Chloramphenicol

Name   of Product

Chloramphenicol




Testing Item

Standard

Result

Conclusion


Characteristic

White   to grayish white or yellow white needle-like crystalline powder or clongated   plate

Complies

Complies


Identification

(Chloramphenicol)

Positive  

Positive

Complies


Melting   Point

149 °C ~   153 °C

151 °C

Complies


Loss   on Drying

≤   0.5%

0.12%

Complies


Residue   on Ignition

≤   0.1%

0.06%

Complies


PH

5.0~   7.5

5.68

Complies


Specific   Rotation

+18.5° ~+21°

+19.5°

Complies


Ralated   Substance

≤   0.5%

<   0.5%

Complies


Chloride

≤   0.01%

0.005%

Complies


Sulphated   Ash

≤   0.1%

0.07%

Complies


Assay:

98.5%~   102.0% Chloramphenicol

99.2%

Complies


CONCLUSION

Comply with BP2010 Standard.









 

Certificate of Analysis: DL- Chloramphenicol

ITEM

SPECIFICATION

RESULT

Characteristics

White or white with greenish-yellowish   crystalline powder

Conforms

Solubility

Moderately soluble in 95% alcohol,very   little soluble in ether and water,practically insoluble chlorophorm

Qualified

Melting range

149~153°C

152.2°C

Acidity or alkalinity

4.5~7.5

6.6

Chloride

≤100ppm

<100ppm

Sulphated

≤0.1%

0.06%

Heavy metals

≤10ppm

<10ppm

Loss on drying

≤0.5%

0.19%

Assay(dried substance)

98.0~102.0% DL-Chloramphenicol

99.28%

Top Quality, Pure Chloramphenicol Powder;  Chloramphenicol Raw Material Supplier in China. Chloramphenicol API Manufacturer. 


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Chloramphenicol CAS 56-75-7 And DL-Chloramphenicol

If you are looking for the chloramphenicol cas 56-75-7 and dl-chloramphenicol, welcome to contact us. We are one of the leading and professional China manufacturers and suppliers in this field. Competitive price and good after-sale service are available.

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Tel: +86-186-7846 1007
WECHAT: +86-18678461007
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Add: Room 1101, 5th Building, No.168 Shenzhen Road, Qingdao, China
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