Sulfadoxine, Sulphadoxine Powder API, Raw Material CAS 2447-57-6
China Sulfadoxine Suppliers, China Sulphadoxine Manufacturers CAS 2447-57-6 Product Name: Sulfadoxine, Sulphadoxine Powder API, Raw Material CAS 2447-57-6 Synonyms: Sulphadoxine CAS Number: 2447-57-6 Characteristics: White or yellowish-white crystals or crystalline powder Assay: 99.0% ~ 101.0% Sulfadoxine Formula: C12H14N4O4S...
China Sulfadoxine Suppliers, China Sulphadoxine Manufacturers CAS 2447-57-6
Product Name: Sulfadoxine (raw material, API)
CAS Number: 2447-57-6
Characteristics: White or yellowish-white crystals or crystalline powder
Assay: 99.0% ~ 101.0% Sulfadoxine
KEY Words: Sulfadoxine, Sulphadoxine API, Raw Material Powder
Sulfadoxine also spells Sulphadoxine, is a long acting sulfonamide. It usually used in combination with pyrimethamine to treat malaria. Some time ago, Sulfadoxine was previously used to prevent malaria. But due to high levels of resistance, this usage is no longer recommended routinely.
Sulfadoxine or Sulphadoxine is usually in combination with other drugs to fight against respiratory, urinary tract, and malarial infections. It is a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid. Sulfadoxine has with bacteriostatic and antimalarial abilities.
Mechanism of Sulfadoxine or Sulphadoxine
Sulfadoxine competes with PABA for the bacterial enzyme dihydropteroate synthase. By this way, it prevents the incorporation of PABA into dihydro folic acid, the immediate precursor of folic acid. This leads to an inhibition of parasitic folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death.
As a professional China Sulfadoxine, Sulphadoxine Powder API, Raw Material supplier and Manufacturer in China, FENGCHEN GROUP CO., LTD has been supplying and exporting Sulfadoxine, Sulphadoxine Powder API, Raw Material from China in China for almost 10 years.
Sulfadoxine, Sulphadoxine Properties:
Sulfadoxine, Sulphadoxine Melting point:190-194°C
storage temp. 2-8°C
Sulfadoxine, Sulphadoxine solubility: Soluble in ethanol & ammonium hydroxide (9:1) at 20mg/ml
4-Amino-N-(5,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide; 4-Sulfanilamido-5,6-dimethoxypyrimidine; 6-(4-Aminobenzenesulfonamide)-4,5-dimethoxypyrimidine; Sulforthomidine; Sulformethoxine, Sulfadoxine
Important safety information of Sulfadoxine, Sulphadoxine powder API, Raw Material:
Sulfadoxine, Sulphadoxine powder API, Raw Material may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous after taken Sulfadoxine, Sulphadoxine powder API, Raw Material. If taken Sulfadoxine, Sulphadoxine alone or together with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
If you have had a severe allergic reaction to Sulfadoxine, Sulphadoxine powder API, Raw Material or any other related sulfonamide substances such as sulfisoxazole, sulfamethoxazole, glyburide, probenecid, contact your professionals before taking Sulfadoxine, Sulphadoxine. Severe reactions may include a severe hives, rash, breathing problems, or dizziness.
Certificate of Analysis (Sulfadoxine)
White or yellowish-white crystals or crystalline powder
Comply with CRS spectrum (EP)
Comply with the CRS spectrum
The residue melts at 80°C~82°C or at 90°C~92°C
About 198°C (EP)
Appearance of solution
≤ Y5, BY5 or GY5
Loss on drying
Residue on ignition
99.0% ~ 101.0%
Conclusion: Comply with BP2011, EP7.0, USP31.
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