Baclofen Powder Raw Material, API CAS 1134-47-0
China Baclofen Suppliers, China Baclofen Manufacturers CAS 1134-47-0 Product Name: Baclofen Powder Raw Material, API CAS 1134-47-0 Synonym s: Baclophen, Baclofeno , Baclofenum , Baclofene CAS Number: 1134-47-0 Characteristics: White to almost white crystalline powder Assay: 99%% ~ 101.0% Baclofen Formula: C10H12ClNO2 Melting Point:...
Baclofen Powder Raw Material, API CAS 1134-47-0
Product Name: Baclofen Powder Raw Material, API
Synonyms: Baclophen, Baclofeno, Baclofenum, Baclofene
CAS Number: 1134-47-0
Characteristics: White to almost white crystalline powder
Assay: 99%% ~ 101.0% Baclofen
Melting Point: 208-210°C
Note: UN 2811 6.1/PG 3
Baclofen Raw Material, API is a central nervous system depressant used as a skeletal muscle relaxant. It is primarily used to treat spasticity. Baclofen Raw Material, API is also used as a muscle relaxant by compounding pharmacies in topical pain creams.
A beneficial property of Baclofen Raw Material, API is that tolerance to its muscle-related therapeutic benefits does not seem to occur to a significant degree (Baclofen Raw Material, API retains its therapeutic anti-spasmodic effects even after many years of continued use). Newer studies, however, indicate that tolerance may develop in some people receiving intrathecal baclofen treatment.
Baclofen Raw Material, API is a gamma-amino-butyric acid (GABA) derivative which is a specific agonist of GABA-B Receptors. It is used to treat Muscle Spasticity, especially that caused by Spinal Cord Injuries. It is believed to act primarily at the spinal cord level by inhibiting spinal polysynaptic afferent pathways and, to a lesser extent, monosynaptic afferent pathways.
Baclofen raw material will be used to produce Baclofen Tablets or other formulations.
Baclofen Raw Material, APIBaclofen Raw Material, API will also relieve Baclofen Raw Material, API will also help to treat arkinson disease, tardive dyskinesia and Huntington disease.
1. Baclofen Raw Material, API itself is a relaxant and antispasmodic agent acting on the skeletal muscle of spinal cord. Suitable for treating multiple-sclerosis bones spasms, spinal infection, degenerated muscle spasms; spinal cord trauma, and neoplastic muscle spasms.
2. Now, Baclofen Raw Material, API is considered to be the most effective muscle relaxants with least side effects.
(1) Baclofen is primarily used to treat spasticity. Now, it is also in the early research stages for treating alcoholism. Baclofen is also used by compounding pharmacies in topical pain creams as a muscle relaxant.
(2) Baclofen, itself, is an agonist for the GABAB receptors. Its beneficial ability in spasticity result from actions at spinal and some other related sites. By the way, Baclofen can also be used to treat hiccups.
(3)A very good property of baclofen is that tolerance does not seem to occur to a significant degree. Baclofen can retain its therapeutic anti-spasmodic properties even after several years usage. However, the most recent researches suggest that tolerance may develop in some patients who are under intrathecal baclofen treatment.
3. Medical uses of Baclofen:
Pharmaceutically, Baclofen is mainly applied for treating spastic movement disorders, especially good for spinal cord injury, cerebral palsy, and multiple sclerosis. It is not suggested to be utilized to the whose who are suffering from stroke or Parkinson's disease.
4. Baclofen Mechanism of action:
similar to the drug GHB, Baclofen will activate the GABAB receptor. However, Baclofen Raw Material, API does not have significant affinity for the GHB receptor, and has no known abuse potential. The modulation of the GABAB receptor is what produces baclofen's range of therapeutic properties.
Baclofen is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:
3.Tightness Or Cramps
6.Motor Neuron Disease
As a professional China Baclofen Raw Material supplier and Manufacturer in China, FENGCHEN GROUP CO., LTD has been supplying and exporting Baclofen API from China in China for almost 10 years.
Baclofen Mechanism of Action and Pharmacology:
Baclofen improves the patient's muscle conditions by acting on the central nervous system.
Baclofen Side effects (Adverse Reactions)
Medicines that contain Baclofen may lead to the unwanted result such as Trembling, Urination Or Pain While Urinating, Confusion Or Hallucinations, Aching Of Limbs, Nausea
Baclofen - Precautions
--Do not drink alcohol after baclofen
--Do not drive or operate heavy machinery or other activities that require mental alertness, after taken Baclofen.
--Do not stop Baclofen suddenly. It is better to stop slowly, reduce the dosage slowly.
--Elder people should pay special attention, before using Baclofen.
Shelf life: 2 years.
COA of Baclofen Raw Material, API
Name of Product
White to almost white crystalline powder
IR or HPLC-- Baclofen
Residual on Ignition
Any Individual Impurity
98.0% ~ 102.0%
Top Quality, China Pure Baclofen Powder/Substance factory in China; China Baclofen Raw Material Supplier in China. China Baclofen API Manufacturer in China.
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