Metronidazole Toxicity, Drug Interactions, Metronidazole Adverse Effect
Toxicity of Metronidazole Raw Material:
LD50=500 mg/kg/day (orally in rat).
Metronidazole Adverse effects:
Reversible peripheral neuropathy with prolonged therapy, CNS toxicity, disulfiram effect with alcohol, dark red-brown urine, metallic taste, nausea, epigastric distress, dizziness, vertigo and paresthesias associated with high doses, and neutropenia (reversible and mild).
Metronidazole Drug Interactions: